Elke Muhlberger, PhD
Associate Professor
Boston University School of Medicine
Dept of Microbiology

PhD, Univ of Marburg
MA, Univ of Marburg



Virologist;
Expert in molecular biology of Marburg and Ebola viruses and other highly pathogenic viruses;
Experienced in BSL4 work;
Focus on virus-host interaction.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences




Point-of-Care Nanotechnology Diagnostic for Differential Fever Diagnosis
10/01/2015 - 10/31/2017 (SP Co-PI of Sub-Project / SP)
PI: John H. Connor, PhD
Becton, Dickinson and Company Paul G. Allen Fdn

Antiviral responses in iPSC-derived human primary cells to Ebola virus infection
06/30/2016 - 05/31/2017 (PI)
NIH/National Institute of Allergy & Infectious Diseases
1R21AI126457-01

National Emerging Infectious Diseases Laboratories Operations
06/01/2016 - 05/31/2017 (PI of Sub-Project / SP)
PI: Ronald B. Corley, Ph.D.
NIH/National Institute of Allergy & Infectious Diseases
2UC7AI095321-03

Deep Characterization of Rousettus Aegyptiacus Immune System: Use of bats/nonhuman primates to compare immune responses during asymtomatic/symptomatic filovirus infections
01/15/2014 - 03/14/2017 (PI)
The Geneva Foundation DOD DTRA

SPR: Novel SPR Barrier Technology (the "USAID Agreement")
11/01/2015 - 10/31/2016 (PI)
SPR Advanced Technologies Inc. USAID

Filovirus replication: initiation mechanism and role of RNA secondary structures
08/05/2014 - 07/31/2016 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R03AI114293-02

Early Host Immune Response in Protection Against Filovirus Infection
06/15/2009 - 05/31/2015 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5U01AI082954-05

IMVC Pilot Project: Mechanisms of Ebola Virus-induced Vascular Dysfunction
05/01/2013 - 04/30/2015 (PI)
Augusta University NIH NIAID
5U01AI083005-05

The Antiviral Function of the Interferon-Simulated Gene IFIT1
05/01/2012 - 04/30/2014 (PI)
Washington University NIH NIAID
5U01AI083005-04




Yr Title Project-Sub Proj Pubs
2016 Antiviral responses in iPSC-derived human primary cells to Ebola virus infection 1R21AI126457-01
2016 Integrated Support Services Core 2UC7AI095321-03-8669 1
2015 Filovirus replication: initiation mechanism and role of RNA secondary structures 5R03AI114293-02 3
2014 Filovirus replication: initiation mechanism and role of RNA secondary structures 1R03AI114293-01 3
2013 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-05 9
2013 Biomolecule Production Core 3UC7AI070088-05S3-6796 1
2012 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-04 9
2012 Biomolecule Production Core 3UC7AI070088-05S2-7836 1
2011 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-03 9
2010 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-02 9
Showing 10 of 11 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Olejnik J, Forero A, Deflubé LR, Hume AJ, Manhart WA, Nishida A, Marzi A, Katze MG, Ebihara H, Rasmussen AL, Mühlberger E. Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages. J Virol. 2017 Jun 01; 91(11).View Related Profiles. PMID: 28331091; DOI: 10.1128/JVI.00179-17;.
  2. Amarasinghe GK, Bào Y, Basler CF, Bavari S, Beer M, Bejerman N, Blasdell KR, Bochnowski A, Briese T, Bukreyev A, Calisher CH, Chandran K, Collins PL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Fang Q, Formenty P, Fouchier RA, Ghedin E, Harding RM, Hewson R, Higgins CM, Hong J, Horie M, James AP, Jiang D, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lee B, Leroy EM, Li M, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Pearson MN, Randall RE, Revill PA, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Smither SJ, Song Q, Stone DM, Takada A, Terregino C, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang B, Wang D, Wang F, Wang LF, Werren JH, Whitfield AE, Yan Z, Ye G, Kuhn JH. Taxonomy of the order Mononegavirales: update 2017. Arch Virol. 2017 Apr 07. PMID: 28389807; DOI: 10.1007/s00705-017-3311-7;.
  3. Nelson EV, Schmidt KM, Deflubé LR, Doganay S, Banadyga L, Olejnik J, Hume AJ, Ryabchikova E, Ebihara H, Kedersha N, Ha T, Mühlberger E. Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. J Virol. 2016 Aug 15; 90(16):7268-84.View Related Profiles. PMID: 27252530; PMCID: PMC4984654; DOI: 10.1128/JVI.00459-16;.
  4. Hume AJ, Ames J, Rennick LJ, Duprex WP, Marzi A, Tonkiss J, Mühlberger E. Inactivation of RNA Viruses by Gamma Irradiation: A Study on Mitigating Factors. Viruses. 2016 Jul 22; 8(7).View Related Profiles. PMID: 27455307; PMCID: PMC4974539; DOI: 10.3390/v8070204;.
  5. Wilson MR, Fedewa G, Stenglein MD, Olejnik J, Rennick LJ, Nambulli S, Feldmann F, Duprex WP, Connor JH, Mühlberger E, DeRisi JL. Multiplexed Metagenomic Deep Sequencing To Analyze the Composition of High-Priority Pathogen Reagents. mSystems. 2016 Jul-Aug; 1(4).View Related Profiles. PMID: 27822544.
  6. Schmidt KM, Mühlberger E. Marburg Virus Reverse Genetics Systems. Viruses. 2016 Jun 22; 8(6).View Related Profiles. PMID: 27338448; PMCID: PMC4926198; DOI: 10.3390/v8060178;.
  7. Afonso CL, Amarasinghe GK, Bányai K, Bào Y, Basler CF, Bavari S, Bejerman N, Blasdell KR, Briand FX, Briese T, Bukreyev A, Calisher CH, Chandran K, Chéng J, Clawson AN, Collins PL, Dietzgen RG, Dolnik O, Domier LL, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Farkas SL, Freitas-Astúa J, Formenty P, Fouchier RA, Fù Y, Ghedin E, Goodin MM, Hewson R, Horie M, Hyndman TH, Jiang D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lenardon S, Leroy EM, Li CX, Lin XD, Liú L, Longdon B, Marton S, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Randall RE, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Shi M, Smither SJ, Stenglein MD, Stone DM, Takada A, Terregino C, Tesh RB, Tian JH, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Verbeek M, Volchkov VE, Wahl-Jensen V, Walsh JA, Walker PJ, Wang D, Wang LF, Wetzel T, Whitfield AE, Xiè JT, Yuen KY, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: update 2016. Arch Virol. 2016 Aug; 161(8):2351-60. PMID: 27216929; PMCID: PMC4947412; DOI: 10.1007/s00705-016-2880-1;.
  8. Brauburger K, Boehmann Y, Krähling V, Mühlberger E. Transcriptional Regulation in Ebola Virus: Effects of Gene Border Structure and Regulatory Elements on Gene Expression and Polymerase Scanning Behavior. J Virol. 2016 Feb; 90(4):1898-909.View Related Profiles. PMID: 26656691; PMCID: PMC4733972; DOI: 10.1128/JVI.02341-15;.
  9. Pinto AK, Williams GD, Szretter KJ, White JP, Proença-Módena JL, Liu G, Olejnik J, Brien JD, Ebihara H, Mühlberger E, Amarasinghe G, Diamond MS, Boon AC. Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families. J Virol. 2015 Sep; 89(18):9465-76.View Related Profiles. PMID: 26157117; PMCID: PMC4542382; DOI: 10.1128/JVI.00996-15;.
  10. Kuhn JH, Andersen KG, Bào Y, Bavari S, Becker S, Bennett RS, Bergman NH, Blinkova O, Bradfute S, Brister JR, Bukreyev A, Chandran K, Chepurnov AA, Davey RA, Dietzgen RG, Doggett NA, Dolnik O, Dye JM, Enterlein S, Fenimore PW, Formenty P, Freiberg AN, Garry RF, Garza NL, Gire SK, Gonzalez JP, Griffiths A, Happi CT, Hensley LE, Herbert AS, Hevey MC, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson JC, Johnson KM, Kindrachuk J, Klenk HD, Kobinger G, Kochel TJ, Lackemeyer MG, Lackner DF, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Omilabu SA, Palacios G, Panchal RG, Park DJ, Patterson JL, Paweska JT, Peters CJ, Pettitt J, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Sabeti PC, Sealfon R, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. Viruses. 2014 Sep; 6(9):3663-82.View Related Profiles. PMID: 25256396; PMCID: PMC4189044; DOI: 10.3390/v6093663;.
Showing 10 of 64 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 64 publications over 24 distinct years, with a maximum of 5 publications in 2013 and 2016

YearPublications
19922
19931
19951
19962
19982
19993
20003
20014
20024
20033
20042
20052
20064
20072
20082
20094
20102
20112
20122
20135
20143
20152
20165
20172

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:


72 E. Concord St Instructional (L)
Boston MA 02118
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