Gustavo Mostoslavsky, MD, PhD
Associate Professor
Boston University School of Medicine
Dept of Medicine
Gastroenterology Section

MD, Universidad Nacional de Tucuman
PhD, The Hebrew University of Jerusalem



Expertise includes: Stem cells; Gene transfer; Lentiviruses; Hematopoietic stem cells; Induced Pluripotent Stem cells.

Associate Professor
Boston University School of Medicine
Department of Microbiology


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Boston Medical Center



2009 NIH RC2 Challenge Award: Role Co-PI
2002-2004 Postdoctoral Award from the Lady Tata Memorial Trust
2000 Travel Allowance Fellowship from Boehringer Ingelheim Fonds
1999-2000 Hebrew University: The Excellency Award as Teaching Assistant at the Department of Microbiology, Faculty of Medicine
1995-1996 The Hebrew University of Jerusalem: Golda Meir Award
1994 Ministry of Science and the Arts of Israel: Ph.D. Fellowship


Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells
07/05/2011 - 06/30/2017 (Co-PI)
PI: Martin H. Steinberg, MD
NIH/National Heart, Lung, and Blood Institute
5U01HL107443-05

Antiviral responses in iPSC-derived human primary cells to Ebola virus infection
06/30/2016 - 05/31/2017 (Co-PI)
PI: Elke Muhlberger, PhD
NIH/National Institute of Allergy & Infectious Diseases
1R21AI126457-01

A National Resource for Lung disease-specific IPS cells
08/15/2014 - 04/30/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
5R24HL123828-03

Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells
07/05/2011 - 06/30/2012 (Co-PI)
PI: Martin H. Steinberg, MD
NIH/National Heart, Lung, and Blood Institute
1U01HL107443-01


Distinct Functional Outcomes or BCR/TLR7 and BCR/TLR9 Co-engagement
03/12/2015 - 02/29/2020 (PI)
UMASS Worcester NIH-NIAMS

The Role of SIRT6 and Metabolism in APC Mediated Tumorigenesis
01/01/2014 - 12/31/2018 (PI)
Mass General Hosp NIH-NCI

Antiviral responses in iPSC-derived human primary cells to Ebola virus infection
06/30/2016 - 05/31/2018 (PI)
Trustees of Boston University NIH-NIAID

Targeting Sequencing and Functional Evaluation of Mutations in Schizophrenia
05/01/2014 - 02/28/2018 (PI)
Northshore University Health System NIH-NIMH

iPSC-derived Repair Fibroblasts to Heal Refractory Venous Ulcers
08/01/2012 - 07/31/2013 (PI)
Tufts University NIH-NIDDK

Characterization of human blood and lung progenitors derived from iPS cells free of reprogramming tr
09/30/2009 - 08/31/2011 (PI)
Trustees of Boston University NIH-NHLBI

Study of Rag 1 hypomorphic mice and their rescue by lentiviral gene transfer
09/30/2008 - 08/31/2011 (PI)
NIH-NICHD
5R21 HD060308-02



Yr Title Project-Sub Proj Pubs
2017 The Role of SIRT6 and Metabolism in APC Mediated Tumorigenesis 5R01CA175727-04 10
2017 The Role of SIRT6 and Metabolism in APC Mediated Tumorigenesis 3R01CA175727-04S1 10
2016 Antiviral responses in iPSC-derived human primary cells to Ebola virus infection 1R21AI126457-01
2016 The Role of SIRT6 and Metabolism in APC Mediated Tumorigenesis 3R01CA175727-03S1 10
2016 A National Resource for Lung disease-specific iPS cells 5R24HL123828-03
2016 The Role of SIRT6 and Metabolism in APC Mediated Tumorigenesis 5R01CA175727-03 10
2015 A National Resource for Lung disease-specific iPS cells 5R24HL123828-02
2015 The Role of SIRT6 and Metabolism in APC Mediated Tumorigenesis 5R01CA175727-02 10
2014 A National Resource for Lung disease-specific iPS cells 1R24HL123828-01
2014 The Role of SIRT6 and Metabolism in APC Mediated Tumorigenesis 1R01CA175727-01A1 10
Showing 10 of 18 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Qiang L, Rao AN, Mostoslavsky G, James MF, Comfort N, Sullivan K, Baas PW. Reprogramming cells from Gulf War veterans into neurons to study Gulf War illness. Neurology. 2017 May 16; 88(20):1968-1975. PMID: 28507260.
  2. Park S, Gianotti-Sommer A, Molina-Estevez FJ, Vanuytsel K, Skvir N, Leung A, Rozelle SS, Shaikho EM, Weir I, Jiang Z, Luo HY, Chui DHK, Figueiredo MS, Alsultan A, Al-Ali A, Sebastiani P, Steinberg MH, Mostoslavsky G, Murphy GJ. A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 Apr 11; 8(4):1076-1085.View Related Profiles. PMID: 28111279; DOI: 10.1016/j.stemcr.2016.12.017;.
  3. Schlimgen R, Howard J, Wooley D, Thompson M, Baden LR, Yang OO, Christiani DC, Mostoslavsky G, Diamond DV, Duane EG, Byers K, Winters T, Gelfand JA, Fujimoto G, Hudson TW, Vyas JM. Risks Associated With Lentiviral Vector Exposures and Prevention Strategies. J Occup Environ Med. 2016 Dec; 58(12):1159-1166. PMID: 27930472.
  4. Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, Mostoslavsky G, Murphy GJ, Patra PK, Chui DH, Alsultan A, Al-Ali AK, Sebastiani P, Steinberg MH. A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. Am J Hematol. 2016 Nov; 91(11):1118-1122.View Related Profiles. PMID: 27501013; DOI: 10.1002/ajh.24527;.
  5. Thomas DD, Sommer AG, Balazs AB, Beerman I, Murphy GJ, Rossi D, Mostoslavsky G. Insulin-like growth factor 2 modulates murine hematopoietic stem cell maintenance through upregulation of p57. Exp Hematol. 2016 May; 44(5):422-433.e1.View Related Profiles. PMID: 26872540; DOI: 10.1016/j.exphem.2016.01.010;.
  6. Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, Bolotina VM. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson''s disease. Nat Commun. 2016; 7:10332.View Related Profiles. PMID: 26755131; PMCID: PMC4729940; DOI: 10.1038/ncomms10332;.
  7. Bar-Nur O, Verheul C, Sommer AG, Brumbaugh J, Schwarz BA, Lipchina I, Huebner AJ, Mostoslavsky G, Hochedlinger K. Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage. Nat Biotechnol. 2015 Jul; 33(7):761-8. PMID: 26098450; PMCID: PMC4840929; DOI: 10.1038/nbt.3247;.
  8. Etchegaray JP, Chavez L, Huang Y, Ross KN, Choi J, Martinez-Pastor B, Walsh RM, Sommer CA, Lienhard M, Gladden A, Kugel S, Silberman DM, Ramaswamy S, Mostoslavsky G, Hochedlinger K, Goren A, Rao A, Mostoslavsky R. The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine. Nat Cell Biol. 2015 May; 17(5):545-57.View Related Profiles. PMID: 25915124; PMCID: PMC4593707; DOI: 10.1038/ncb3147;.
  9. Wilson AA, Ying L, Liesa M, Segeritz CP, Mills JA, Shen SS, Jean J, Lonza GC, Liberti DC, Lang AH, Nazaire J, Gower AC, Müeller FJ, Mehta P, Ordóñez A, Lomas DA, Vallier L, Murphy GJ, Mostoslavsky G, Spira A, Shirihai OS, Ramirez MI, Gadue P, Kotton DN. Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells. Stem Cell Reports. 2015 May 12; 4(5):873-85.View Related Profiles. PMID: 25843048; PMCID: PMC4437473; DOI: 10.1016/j.stemcr.2015.02.021;.
  10. Alajem A, Biran A, Harikumar A, Sailaja BS, Aaronson Y, Livyatan I, Nissim-Rafinia M, Sommer AG, Mostoslavsky G, Gerbasi VR, Golden DE, Datta A, Sze SK, Meshorer E. Differential association of chromatin proteins identifies BAF60a/SMARCD1 as a regulator of embryonic stem cell differentiation. Cell Rep. 2015 Mar 31; 10(12):2019-31. PMID: 25818293; DOI: 10.1016/j.celrep.2015.02.064;.
Showing 10 of 63 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 63 publications over 18 distinct years, with a maximum of 8 publications in 2010

YearPublications
19981
19991
20011
20021
20042
20052
20065
20075
20081
20093
20108
20116
20126
20137
20144
20154
20164
20172
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

stem cells

Available to Mentor as: (Review Mentor Role Definitions):
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:


670 Albany St Biosquare III
Boston MA 02118
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