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Last Name

Tova Meshulam, PhD

TitleResearch Assistant Professor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionGastroenterology
Address650 Albany St Evans Biomed Research Ctr
Boston MA 02118
Phone(617) 638-6713
ORCID ORCID Icon0000-0002-7635-0328
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Meshulam T, Breen MR, Liu L, Parton RG, Pilch PF. Caveolins/caveolae protect adipocytes from fatty acid-mediated lipotoxicity. J Lipid Res. 2011 Aug; 52(8):1526-32.
    View in: PubMed
  2. Simard JR, Meshulam T, Pillai BK, Kirber MT, Brunaldi K, Xu S, Pilch PF, Hamilton JA. Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity. J Lipid Res. 2010 May; 51(5):914-22.
    View in: PubMed
  3. Meshulam T, Simard JR, Wharton J, Hamilton JA, Pilch PF. Role of caveolin-1 and cholesterol in transmembrane fatty acid movement. Biochemistry. 2006 Mar 7; 45(9):2882-93.
    View in: PubMed
  4. Joseph-McCarthy D, Parris K, Huang A, Failli A, Quagliato D, Dushin EG, Novikova E, Severina E, Tuckman M, Petersen PJ, Dean C, Fritz CC, Meshulam T, DeCenzo M, Dick L, McFadyen IJ, Somers WS, Lovering F, Gilbert AM. Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors. J Med Chem. 2005 Dec 15; 48(25):7960-9.
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  5. Wharton J, Meshulam T, Vallega G, Pilch P. Dissociation of insulin receptor expression and signaling from caveolin-1 expression. J Biol Chem. 2005 Apr 8; 280(14):13483-6.
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  6. Christin L, Wysong DR, Meshulam T, Hastey R, Simons ER, Diamond RD. Human platelets damage Aspergillus fumigatus hyphae and may supplement killing by neutrophils. Infect Immun. 1998 Mar; 66(3):1181-9.
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  7. Christin L, Wysong DR, Meshulam T, Wang S, Diamond RD. Mechanisms and target sites of damage in killing of Candida albicans hyphae by human polymorphonuclear neutrophils. J Infect Dis. 1997 Dec; 176(6):1567-78.
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  8. Meshulam T, Levitz SM, Christin L, Diamond RD. A simplified new assay for assessment of fungal cell damage with the tetrazolium dye, (2,3)-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanil ide (XTT). J Infect Dis. 1995 Oct; 172(4):1153-6.
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  9. Strohmeier GR, Brunkhorst BA, Seetoo KF, Meshulam T, Bernardo J, Simons ER. Role of the Fc gamma R subclasses Fc gamma RII and Fc gamma RIII in the activation of human neutrophils by low and high valency immune complexes. J Leukoc Biol. 1995 Oct; 58(4):415-22.
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  10. Meshulam T, Billah MM, Eckel S, Griendling KK, Diamond RD. Relationship of phospholipase C- and phospholipase D-mediated phospholipid remodeling pathways to respiratory burst activation in human neutrophils stimulated by Candida albicans hyphae. J Leukoc Biol. 1995 Jun; 57(6):842-50.
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  11. Meshulam T, Herscovitz H, Casavant D, Bernardo J, Roman R, Haugland RP, Strohmeier GS, Diamond RD, Simons ER. Flow cytometric kinetic measurements of neutrophil phospholipase A activation. J Biol Chem. 1992 Oct 25; 267(30):21465-70.
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  12. Smail EH, Cronstein BN, Meshulam T, Esposito AL, Ruggeri RW, Diamond RD. In vitro, Candida albicans releases the immune modulator adenosine and a second, high-molecular weight agent that blocks neutrophil killing. J Immunol. 1992 Jun 1; 148(11):3588-95.
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  13. Meshulam T, Levitz SM, Diamond RD, Sugar AM. Effect of cilofungin (LY121019), a fungal cell wall synthesis inhibitor, on interactions of Candida albicans with human neutrophils. J Antimicrob Chemother. 1989 Nov; 24(5):741-5.
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  14. Etzioni A, Hochberg Z, Pollak S, Meshulam T, Zakut V, Tzehoval E, Keisari Y, Aviram I, Spirer Z, Benderly A, et al. Defective leukocyte fungicidal activity in end-organ resistance to 1,25-dihydroxyvitamin D. Pediatr Res. 1989 Mar; 25(3):276-9.
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  15. Picard M, Meshulam T, Sugar AM. In vitro activity of LY121019 against Candida species and Torulopsis glabrata. Eur J Clin Microbiol Infect Dis. 1988 Jun; 7(3):432-3.
    View in: PubMed
  16. Pothoulakis C, Sullivan R, Melnick DA, Triadafilopoulos G, Gadenne AS, Meshulam T, LaMont JT. Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes. J Clin Invest. 1988 Jun; 81(6):1741-5.
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  17. Meshulam T, Diamond RD, Lyman CA, Wysong DR, Melnick DA. Temporal association of calcium mobilization, inositol trisphosphate generation, and superoxide anion release by human neutrophils activated by serum opsonized and nonopsonized particulate stimuli. Biochem Biophys Res Commun. 1988 Jan 29; 150(2):532-9.
    View in: PubMed
  18. Sullivan R, Griffin JD, Simons ER, Schafer AI, Meshulam T, Fredette JP, Maas AK, Gadenne AS, Leavitt JL, Melnick DA. Effects of recombinant human granulocyte and macrophage colony-stimulating factors on signal transduction pathways in human granulocytes. J Immunol. 1987 Nov 15; 139(10):3422-30.
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  19. Sullivan R, Melnick DA, Malech HL, Meshulam T, Simons ER, Lazzari KG, Proto PJ, Gadenne AS, Leavitt JL, Griffin JD. The effects of phorbol myristate acetate and chemotactic peptide on transmembrane potentials and cytosolic free calcium in mature granulocytes evolve sequentially as the cells differentiate. J Biol Chem. 1987 Jan 25; 262(3):1274-81.
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  20. Etzioni A, Meshulam T, Zeltzer M, Benderly A, Merzbach D, Sujov P. Intralipid effects on preterm neonate serum: chemoattractant and opsonizing capacities. J Pediatr Gastroenterol Nutr. 1987 Jan-Feb; 6(1):105-8.
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  21. Meshulam T, Proto P, Diamond RD, Melnick DA. Calcium modulation and chemotactic response: divergent stimulation of neutrophil chemotaxis and cytosolic calcium response by the chemotactic peptide receptor. J Immunol. 1986 Sep 15; 137(6):1954-60.
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  22. Melnick DA, Meshulam T, Manto A, Malech HL. Activation of human neutrophils by monoclonal antibody PMN7C3: cell movement and adhesion can be triggered independently from the respiratory burst. Blood. 1986 May; 67(5):1388-94.
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  23. Vardi Y, Meshulam T, Obedeanu N, Merzbach D, Levin DR. Escherichia coli adherence to human transitional cell tumors: a simple research model of bacterial attachment to the lower urinary tract. Eur Urol. 1986; 12(6):432-7.
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  24. Apfeldorf WJ, Melnick DA, Meshulam T, Rasmussen H, Malech HL. A transient rise in intracellular free calcium is not a sufficient stimulus for respiratory burst activation in human polymorphonuclear leukocytes. Biochem Biophys Res Commun. 1985 Oct 30; 132(2):674-80.
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  25. Friedman-Birnbaum R, Bergman R, Obedeanu N, Meshulam T, Merzbach D. Neutrophil migration in granuloma annulare: comparative study between localized and generalized types and between active and regressive states. J Dermatol. 1985 Oct; 12(5):455-8.
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  26. Meshulam T, Obedeanu N, Merzbach D, Sobel JD. Phagocytosis of mucoid and nonmucoid strains of Pseudomonas aeruginosa. Clin Immunol Immunopathol. 1984 Aug; 32(2):151-65.
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  27. Vardi Y, Meshulam T, Obedeanu N, Merzbach D, Sobel JD. In vivo adherence of Pseudomonas aeruginosa to rat bladder epithelium. Proc Soc Exp Biol Med. 1983 Apr; 172(4):449-56.
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  28. Scharf J, Meshulam T, Obedeanu N, Nahir M, Zonis S, Merzbach D. Lysozyme concentration in tears of patients with sicca syndrome. Ann Ophthalmol. 1982 Nov; 14(11):1063-4.
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  29. Meshulam T, Verbrugh HA, Verhoef J. Opsonization and phagocytosis of mucoid and non-mucoid Pseudomonas aeruginosa strains. Eur J Clin Microbiol. 1982 Apr; 1(2):112-7.
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  30. Meshulam T, Verbrugh H, Verhoef J. Serum-induced lysis of Pseudomonas aeruginosa. Eur J Clin Microbiol. 1982 Feb; 1(1):1-6.
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  31. Scharf JM, Obedeanu N, Meshulam T, Nahir M, Merzbach D, Scharf JA, Zonis S. Influence of bromhexine on tear lysozome level in keratoconjunctivitis sicca. Am J Ophthalmol. 1981 Jul; 92(1):21-3.
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  32. Segal AW, Meshulam T. Production of superoxide by neutrophils: a reappraisal. FEBS Lett. 1979 Apr 1; 100(1):27-32.
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  33. Haim N, Obedeanu N, Meshulam T, Robinson E, Ben-Layish E, Merzbach D. Comparative study of the endotoxin-stimulated nitroblue tetrazolium test in disease and health. J Clin Pathol. 1978 Dec; 31(12):1249-52.
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  34. Haim N, Obedeanu N, Meshulam T, Robinson E, Schreiber H, Merzbach D. Neutrophil function in cured cancer patients. Cancer. 1977 Nov; 40(5):2273-7.
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  35. Haim N, Obedeanu N, Meshulam T, Robinson E, Merzbach D. Spontaneous and stimulated nitroblue tetrazolium tests of leukocytes from patients with solid malignant tumors. Am J Clin Pathol. 1977 Nov; 68(5):570-4.
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  36. Sobel JD, Haim S, Obedeanu N, Meshulam T, Merzbach D. Polymorphonuclear leucocyte function in Beh├žet's disease. J Clin Pathol. 1977 Mar; 30(3):250-3.
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