Keywords
Last Name

Domenic A. Ciraulo, MD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentPsychiatry
Address720 Harrison Ave
Boston MA 02118
Phone(617) 638-8141
ORCID ORCID Icon0000-0001-7706-8765
Other Positions
TitleChair of General Psychiatry
InstitutionBoston University School of Medicine
DepartmentPsychiatry

TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Graduate Medical Sciences

TitleActive Staff Privileges
InstitutionBoston Medical Center
DepartmentPsychiatry

 Research Expertise & Professional Interests
Dr. Ciraulo has been Professor and Chairman of the Division of Psychiatry and Psychiatrist-in Chief at Boston Medical Center since 1996. He leads a research team that studies alcoholism and addiction. Research support for his work has been provided by NIAAA, NIDA, and the Department of Veterans Affairs. His research in alcoholism and addiction has focused on medication development, the interaction of psychosocial therapy and medication therapy, neuroimaging, and clinical psychopharmacology.

Dr. Ciraulo has served on several national committees, including FDA advisory panels, NIH scientific review groups, and the American Psychiatry Association’s Council on Addiction Psychiatry. He is Associate Editor of the Journal of Clinical Psychopharmacology and serves on the editorial board of the American Journal of Drug and Alcohol Abuse.

Dr. Ciraulo has authored or co-authored more than one hundred fifty papers and book chapters and co-edited five books. He is also a Lecturer on Psychiatry at Harvard Medical School and an Adjunct Lecturer in Pharmacology and Experimental Therapeutics at Tufts University School of Medicine. He was formerly a Professor of Psychiatry at Tufts (1992-96). He graduated from Georgetown University School of Medicine in 1975 and was a psychiatric resident at the Institute of Living (1975-77) and Chief Resident of the Somatic Therapies Unit, Clinical Fellow Harvard Medical School, Massachusetts Mental Health Center (1977-78).

Dr. Ciraulo's expertise includes: Clinical pharmacology of addictive disorders; Non-invasive brain stimulation; Medication development.

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Fecteau S, Agosta S, Hone-Blanchet A, Fregni F, Boggio P, Ciraulo D, Pascual-Leone A. Modulation of smoking and decision-making behaviors with transcranial direct current stimulation in tobacco smokers: A preliminary study. Drug Alcohol Depend. 2014 Jul 1; 140:78-84.
    View in: PubMed
  2. Knapp CM, O''Malley M, Datta S, Ciraulo DA. The Kv7 potassium channel activator retigabine decreases alcohol consumption in rats. Am J Drug Alcohol Abuse. 2014 May; 40(3):244-50.
    View in: PubMed
  3. Oldham MA, Ciraulo DA. Bright light therapy for depression: A review of its effects on chronobiology and the autonomic nervous system. Chronobiol Int. 2014 Apr; 31(3):305-19.
    View in: PubMed
  4. Ciraulo DA, Barlow DH, Gulliver SB, Farchione T, Morissette SB, Kamholz BW, Eisenmenger K, Brown B, Devine E, Brown TA, Knapp CM. The effects of venlafaxine and cognitive behavioral therapy alone and combined in the treatment of co-morbid alcohol use-anxiety disorders. Behav Res Ther. 2013 Nov; 51(11):729-35.
    View in: PubMed
  5. Devine EG, Waters ME, Putnam M, Surprise C, O''Malley K, Richambault C, Fishman RL, Knapp CM, Patterson EH, Sarid-Segal O, Streeter C, Colanari L, Ciraulo DA. Concealment and fabrication by experienced research subjects. Clin Trials. 2013; 10(6):935-48.
    View in: PubMed
  6. Litten RZ, Ryan ML, Fertig JB, Falk DE, Johnson B, Dunn KE, Green AI, Pettinati HM, Ciraulo DA, Sarid-Segal O, Kampman K, Brunette MF, Strain EC, Tiouririne NA, Ransom J, Scott C, Stout R. A double-blind, placebo-controlled trial assessing the efficacy of varenicline tartrate for alcohol dependence. J Addict Med. 2013 Jul-Aug; 7(4):277-86.
    View in: PubMed
  7. Somoza EC, Winship D, Gorodetzky CW, Lewis D, Ciraulo DA, Galloway GP, Segal SD, Sheehan M, Roache JD, Bickel WK, Jasinski D, Watson DW, Miller SR, Somoza P, Winhusen T. A multisite, double-blind, placebo-controlled clinical trial to evaluate the safety and efficacy of vigabatrin for treating cocaine dependence. JAMA Psychiatry. 2013 Jun; 70(6):630-7.
    View in: PubMed
  8. O'Malley MW, Fishman RL, Ciraulo DA, Datta S. Effect of five-consecutive-day exposure to an anxiogenic stressor on sleep-wake activity in rats. Front Neurol. 2013; 4:15.
    View in: PubMed
  9. Streeter CC, Gerbarg PL, Saper RB, Ciraulo DA, Brown RP. Effects of yoga on the autonomic nervous system, gamma-aminobutyric-acid, and allostasis in epilepsy, depression, and post-traumatic stress disorder. Med Hypotheses. 2012 May; 78(5):571-9.
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  10. Fertig JB, Ryan ML, Falk DE, Litten RZ, Mattson ME, Ransom J, Rickman WJ, Scott C, Ciraulo D, Green AI, Tiouririne NA, Johnson B, Pettinati H, Strain EC, Devine E, Brunette MF, Kampman K, A Tompkins D, Stout R. A double-blind, placebo-controlled trial assessing the efficacy of levetiracetam extended-release in very heavy drinking alcohol-dependent patients. Alcohol Clin Exp Res. 2012 Aug; 36(8):1421-30.
    View in: PubMed
  11. Afshar M, Knapp CM, Sarid-Segal O, Devine E, Colaneri LS, Tozier L, Waters ME, Putnam MA, Ciraulo DA. The efficacy of mirtazapine in the treatment of cocaine dependence with comorbid depression. Am J Drug Alcohol Abuse. 2012 Mar; 38(2):181-6.
    View in: PubMed
  12. Litten RZ, Fertig JB, Falk DE, Ryan ML, Mattson ME, Collins JF, Murtaugh C, Ciraulo D, Green AI, Johnson B, Pettinati H, Swift R, Afshar M, Brunette MF, Tiouririne NA, Kampman K, Stout R. A double-blind, placebo-controlled trial to assess the efficacy of quetiapine fumarate XR in very heavy-drinking alcohol-dependent patients. Alcohol Clin Exp Res. 2012 Mar; 36(3):406-16.
    View in: PubMed
  13. Streeter CC, Whitfield TH, Owen L, Rein T, Karri SK, Yakhkind A, Perlmutter R, Prescot A, Renshaw PF, Ciraulo DA, Jensen JE. Effects of yoga versus walking on mood, anxiety, and brain GABA levels: a randomized controlled MRS study. J Altern Complement Med. 2010 Nov; 16(11):1145-52.
    View in: PubMed
  14. Knapp CM, Sarid-Segal O, Richardson MA, Colaneri LS, Afshar M, Devine E, Streeter CC, Piechniczek-Buczek J, Ciraulo DA. Open label trial of the tolerability and efficacy of zonisamide in the treatment of alcohol dependence. Am J Drug Alcohol Abuse. 2010 Mar; 36(2):102-5.
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  15. Anderson AL, Reid MS, Li SH, Holmes T, Shemanski L, Slee A, Smith EV, Kahn R, Chiang N, Vocci F, Ciraulo D, Dackis C, Roache JD, Salloum IM, Somoza E, Urschel HC, Elkashef AM. Modafinil for the treatment of cocaine dependence. Drug Alcohol Depend. 2009 Sep 1; 104(1-2):133-9.
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  16. Knapp CM, Tozier L, Pak A, Ciraulo DA, Kornetsky C. Deep brain stimulation of the nucleus accumbens reduces ethanol consumption in rats. Pharmacol Biochem Behav. 2009 May; 92(3):474-9.
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  17. Sarid-Segal O, Knapp CM, Burch W, Richardson MA, Bahtia S, DeQuattro K, Afshar M, Richambault C, Sickels L, Devine E, Ciraulo DA. The anticonvulsant zonisamide reduces ethanol self-administration by risky drinkers. Am J Drug Alcohol Abuse. 2009; 35(5):316-9.
    View in: PubMed
  18. Vassoler FM, Schmidt HD, Gerard ME, Famous KR, Ciraulo DA, Kornetsky C, Knapp CM, Pierce RC. Deep brain stimulation of the nucleus accumbens shell attenuates cocaine priming-induced reinstatement of drug seeking in rats. J Neurosci. 2008 Aug 27; 28(35):8735-9.
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  19. Zweben A, Pettinati HM, Weiss RD, Youngblood M, Cox CE, Mattson ME, Gorroochurn P, Ciraulo D. Relationship between medication adherence and treatment outcomes: the COMBINE study. Alcohol Clin Exp Res. 2008 Sep; 32(9):1661-9.
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  20. Morissette SB, Gulliver SB, Kamholz BW, Duade J, Farchione T, Devine E, Brown TA, Barlow DH, Ciraulo D. Differences between daily smokers, chippers, and nonsmokers with co-occurring anxiety and alcohol-use disorders. Addict Behav. 2008 Nov; 33(11):1425-31.
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  21. Johnson BA, Rosenthal N, Capece JA, Wiegand F, Mao L, Beyers K, McKay A, Ait-Daoud N, Addolorato G, Anton RF, Ciraulo DA, Kranzler HR, Mann K, O'Malley SS, Swift RM. Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial. Arch Intern Med. 2008 Jun 9; 168(11):1188-99.
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  22. Ciraulo DA, Dong Q, Silverman BL, Gastfriend DR, Pettinati HM. Early treatment response in alcohol dependence with extended-release naltrexone. J Clin Psychiatry. 2008 Feb; 69(2):190-5.
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  23. Sarid-Segal O, Piechniczek-Buczek J, Knapp C, Afshar M, Devine E, Sickles L, Uwodukunda E, Richambault C, Koplow J, Ciraulo D. The effects of levetiracetam on alcohol consumption in alcohol-dependent subjects: an open label study. Am J Drug Alcohol Abuse. 2008; 34(4):441-7.
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  24. Johnson BA, Rosenthal N, Capece JA, Wiegand F, Mao L, Beyers K, McKay A, Ait-Daoud N, Anton RF, Ciraulo DA, Kranzler HR, Mann K, O'Malley SS, Swift RM. Topiramate for treating alcohol dependence: a randomized controlled trial. JAMA. 2007 Oct 10; 298(14):1641-51.
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  25. Winhusen T, Somoza E, Ciraulo DA, Harrer JM, Goldsmith RJ, Grabowski J, Coleman FS, Mindrum G, Kahn R, Osman S, Mezinskis J, Li SH, Lewis D, Horn P, Montgomery MA, Elkashef A. A double-blind, placebo-controlled trial of tiagabine for the treatment of cocaine dependence. Drug Alcohol Depend. 2007 Dec 1; 91(2-3):141-8.
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  26. Winhusen T, Somoza E, Sarid-Segal O, Goldsmith RJ, Harrer JM, Coleman FS, Kahn R, Osman S, Mezinskis J, Li SH, Lewis D, Afshar M, Ciraulo DA, Horn P, Montgomery MA, Elkashef A. A double-blind, placebo-controlled trial of reserpine for the treatment of cocaine dependence. Drug Alcohol Depend. 2007 Dec 1; 91(2-3):205-12.
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  27. Streeter CC, Terhune DB, Whitfield TH, Gruber S, Sarid-Segal O, Silveri MM, Tzilos G, Afshar M, Rouse ED, Tian H, Renshaw PF, Ciraulo DA, Yurgelun-Todd DA. Performance on the Stroop predicts treatment compliance in cocaine-dependent individuals. Neuropsychopharmacology. 2008 Mar; 33(4):827-36.
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  28. Kaufman MJ, Streeter CC, Barros TL, Sarid-Segal O, Afshar M, Tian H, Rouse ED, Foy KK, Brimson ML, Archambault CA, Renshaw PF, Ciraulo DA. Reduced Plasma Nitric Oxide End Products in Cocaine-dependent Men. J Addict Med. 2007 Jun; 1(2):96-103.
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  29. Streeter CC, Jensen JE, Perlmutter RM, Cabral HJ, Tian H, Terhune DB, Ciraulo DA, Renshaw PF. Yoga Asana sessions increase brain GABA levels: a pilot study. J Altern Complement Med. 2007 May; 13(4):419-26.
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  30. Knapp CM, Mercado M, Markley TL, Crosby S, Ciraulo DA, Kornetsky C. Zonisamide decreases ethanol intake in rats and mice. Pharmacol Biochem Behav. 2007 May; 87(1):65-72.
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  31. Sim ME, Lyoo IK, Streeter CC, Covell J, Sarid-Segal O, Ciraulo DA, Kim MJ, Kaufman MJ, Yurgelun-Todd DA, Renshaw PF. Cerebellar gray matter volume correlates with duration of cocaine use in cocaine-dependent subjects. Neuropsychopharmacology. 2007 Oct; 32(10):2229-37.
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  32. Knapp CM, Datta S, Ciraulo DA, Kornetsky C. Effects of low dose cocaine on REM sleep in the freely moving rat. Sleep Biol Rhythms. 2007 Jan; 5(1):55-62.
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  33. Culpepper L, Judd CR, Moller MD, Nemeroff CB, Rapaport MH, Ciraulo DA. Clinicians on the front line: active management of depression and anxiety in primary care. JAAPA. 2006 Jul; Suppl:4-21; quiz 22.
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  34. Anton RF, O'Malley SS, Ciraulo DA, Cisler RA, Couper D, Donovan DM, Gastfriend DR, Hosking JD, Johnson BA, LoCastro JS, Longabaugh R, Mason BJ, Mattson ME, Miller WR, Pettinati HM, Randall CL, Swift R, Weiss RD, Williams LD, Zweben A. Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA. 2006 May 3; 295(17):2003-17.
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  35. Ciraulo DA, Hitzemann RJ, Somoza E, Knapp CM, Rotrosen J, Sarid-Segal O, Ciraulo AM, Greenblatt DJ, Chiang CN. Pharmacokinetics and pharmacodynamics of multiple sublingual buprenorphine tablets in dose-escalation trials. J Clin Pharmacol. 2006 Feb; 46(2):179-92.
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  36. Streeter CC, Hennen J, Ke Y, Jensen JE, Sarid-Segal O, Nassar LE, Knapp C, Meyer AA, Kwak T, Renshaw PF, Ciraulo DA. Prefrontal GABA levels in cocaine-dependent subjects increase with pramipexole and venlafaxine treatment. Psychopharmacology (Berl). 2005 Nov; 182(4):516-26.
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  37. Ciraulo DA, Sarid-Segal O, Knapp CM, Ciraulo AM, LoCastro J, Bloch DA, Montgomery MA, Leiderman DB, Elkashef A. Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence. Addiction. 2005 Mar; 100 Suppl 1:12-22.
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  38. Ciraulo DA, Knapp C, Rotrosen J, Sarid-Segal O, Ciraulo AM, LoCastro J, Greenblatt DJ, Leiderman D. Nefazodone treatment of cocaine dependence with comorbid depressive symptoms. Addiction. 2005 Mar; 100 Suppl 1:23-31.
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  39. Kampman KM, Leiderman D, Holmes T, LoCastro J, Bloch DA, Reid MS, Shoptaw S, Montgomery MA, Winhusen TM, Somoza EC, Ciraulo DA, Elkashef A, Vocci F. Cocaine Rapid Efficacy Screening Trials (CREST): lessons learned. Addiction. 2005 Mar; 100 Suppl 1:102-10.
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  40. Elkashef A, Holmes TH, Bloch DA, Shoptaw S, Kampman K, Reid MS, Somoza E, Ciraulo D, Rotrosen J, Leiderman D, Montgomery A, Vocci F. Retrospective analyses of pooled data from CREST I and CREST II trials for treatment of cocaine dependence. Addiction. 2005 Mar; 100 Suppl 1:91-101.
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  41. Johnson BA, Swift RM, Addolorato G, Ciraulo DA, Myrick H. Safety and efficacy of GABAergic medications for treating alcoholism. Alcohol Clin Exp Res. 2005 Feb; 29(2):248-54.
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  42. Monnelly EP, Ciraulo DA, Knapp C, LoCastro J, Sepulveda I. Quetiapine for treatment of alcohol dependence. J Clin Psychopharmacol. 2004 Oct; 24(5):532-5.
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  43. Lyoo IK, Streeter CC, Ahn KH, Lee HK, Pollack MH, Silveri MM, Nassar L, Levin JM, Sarid-Segal O, Ciraulo DA, Renshaw PF, Kaufman MJ. White matter hyperintensities in subjects with cocaine and opiate dependence and healthy comparison subjects. Psychiatry Res. 2004 Jul 30; 131(2):135-45.
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  44. Ke Y, Streeter CC, Nassar LE, Sarid-Segal O, Hennen J, Yurgelun-Todd DA, Awad LA, Rendall MJ, Gruber SA, Nason A, Mudrick MJ, Blank SR, Meyer AA, Knapp C, Ciraulo DA, Renshaw PF. Frontal lobe GABA levels in cocaine dependence: a two-dimensional, J-resolved magnetic resonance spectroscopy study. Psychiatry Res. 2004 Apr 30; 130(3):283-93.
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  45. Somoza EC, Winhusen TM, Bridge TP, Rotrosen JP, Vanderburg DG, Harrer JM, Mezinskis JP, Montgomery MA, Ciraulo DA, Wulsin LR, Barrett JA. An open-label pilot study of methylphenidate in the treatment of cocaine dependent patients with adult attention deficit/hyperactivity disorder. J Addict Dis. 2004; 23(1):77-92.
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  46. Ciraulo DA, Piechniczek-Buczek J, Iscan EN. Outcome predictors in substance use disorders. Psychiatr Clin North Am. 2003 Jun; 26(2):381-409.
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  47. Johnson BA, O'Malley SS, Ciraulo DA, Roache JD, Chambers RA, Sarid-Segal O, Couper D. Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects. J Clin Psychopharmacol. 2003 Jun; 23(3):281-93.
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  48. Monnelly EP, Ciraulo DA, Knapp C, Keane T. Low-dose risperidone as adjunctive therapy for irritable aggression in posttraumatic stress disorder. J Clin Psychopharmacol. 2003 Apr; 23(2):193-6.
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  49. Streeter CC, Gulliver SB, Baker E, Blank SR, Meyer AA, Ciraulo DA, Renshaw PF. Videotaped cue for urge to drink alcohol. Alcohol Clin Exp Res. 2002 May; 26(5):627-34.
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  50. Knapp CM, Lee K, Foye M, Ciraulo DA, Kornetsky C. Additive effects of intra-accumbens infusion of the cAMP-specific phosphodiesterase inhibitor, rolipram and cocaine on brain stimulation reward. Life Sci. 2001 Aug 24; 69(14):1673-82.
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  51. Ciraulo DA, Knapp CM, LoCastro J, Greenblatt DJ, Shader RI. A benzodiazepine mood effect scale: reliability and validity determined for alcohol-dependent subjects and adults with a parental history of alcoholism. Am J Drug Alcohol Abuse. 2001 May; 27(2):339-47.
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  52. Knapp CM, Foye MM, Cottam N, Ciraulo DA, Kornetsky C. Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self-administration. Pharmacol Biochem Behav. 2001 Apr; 68(4):797-803.
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  53. LoCastro J, Spiro A, Monnelly E, Ciraulo D. Personality, family history, and alcohol use among older men: the VA Normative Aging Study. Alcohol Clin Exp Res. 2000 Apr; 24(4):501-11.
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  54. Sarid-Segal O, Knapp CM, Ciraulo AM, Greenblatt DJ, Shader RI, Ciraulo DA. Decreased EEG sensitivity to alprazolam in subjects with a parental history of alcoholism. J Clin Pharmacol. 2000 Jan; 40(1):84-90.
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  55. Ciraulo DA, Nace EP. Benzodiazepine treatment of anxiety or insomnia in substance abuse patients. Am J Addict. 2000; 9(4):276-9; discussion 280-4.
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  56. Monnelly EP, Ciraulo DA. Risperidone effects on irritable aggression in posttraumatic stress disorder. J Clin Psychopharmacol. 1999 Aug; 19(4):377-8.
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  57. Knapp CM, Foye MM, Ciraulo DA, Kornetsky C. The type IV phosphodiesterase inhibitors, Ro 20-1724 and rolipram, block the initiation of cocaine self-administration. Pharmacol Biochem Behav. 1999 Jan; 62(1):151-8.
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  58. von Moltke LL, Greenblatt DJ, Ciraulo DA, Grassi JM, Granda BW, Duan SX, Harmatz JS, Shader RI. Appetite suppressant drugs as inhibitors of human cytochromes P450: in vitro inhibition of P450-2D6 by D- and L-fenfluramine, but not phentermine. J Clin Psychopharmacol. 1998 Aug; 18(4):338-41.
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  59. Cowell VL, Ciraulo D, Gabram S, Lawrence D, Cortes V, Edwards T, Jacobs L. Trauma 24-hour observation critical path. J Trauma. 1998 Jul; 45(1):147-50.
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  60. Streeter CC, Ciraulo DA, Harris GJ, Kaufman MJ, Lewis RF, Knapp CM, Ciraulo AM, Maas LC, Ungeheuer M, Szulewski S, Renshaw PF. Functional magnetic resonance imaging of alprazolam-induced changes in humans with familial alcoholism. Psychiatry Res. 1998 May 20; 82(2):69-82.
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  61. Ciraulo DA, Barnhill JG, Ciraulo AM, Sarid-Segal O, Knapp C, Greenblatt DJ, Shader RI. Alterations in pharmacodynamics of anxiolytics in abstinent alcoholic men: subjective responses, abuse liability, and electroencephalographic effects of alprazolam, diazepam, and buspirone. J Clin Pharmacol. 1997 Jan; 37(1):64-73.
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  62. Ciraulo DA, Sarid-Segal O, Knapp C, Ciraulo AM, Greenblatt DJ, Shader RI. Liability to alprazolam abuse in daughters of alcoholics. Am J Psychiatry. 1996 Jul; 153(7):956-8.
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  63. Goff DC, Amico E, Dreyfuss D, Ciraulo D. A placebo-controlled trial of trihexyphenidyl in unmedicated patients with schizophrenia. Am J Psychiatry. 1994 Mar; 151(3):429-31.
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  64. Sellers EM, Ciraulo DA, DuPont RL, Griffiths RR, Kosten TR, Romach MK, Woody GE. Alprazolam and benzodiazepine dependence. J Clin Psychiatry. 1993 Oct; 54 Suppl:64-75; discussion 76-7.
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  65. Greenblatt DJ, von Moltke LL, Harmatz JS, Ciraulo DA, Shader RI. Alprazolam pharmacokinetics, metabolism, and plasma levels: clinical implications. J Clin Psychiatry. 1993 Oct; 54 Suppl:4-11; discussion 12-4.
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  66. Goff DC, Renshaw PF, Sarid-Segal O, Dreyfuss DA, Amico ET, Ciraulo DA. A placebo-controlled trial of selegiline (L-deprenyl) in the treatment of tardive dyskinesia. Biol Psychiatry. 1993 May 15; 33(10):700-6.
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  67. Sands BF, Ciraulo DA. Cocaine drug-drug interactions. J Clin Psychopharmacol. 1992 Feb; 12(1):49-55.
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  68. Barnhill JG, Ciraulo DA, Greenblatt DJ, Faggart MA, Harmatz JS. Benzodiazepine response and receptor binding after chronic ethanol ingestion in a mouse model. J Pharmacol Exp Ther. 1991 Sep; 258(3):812-9.
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  69. Barnhill JG, Miller LG, Greenblatt DJ, Thompson ML, Ciraulo DA, Shader RI. Benzodiazepine receptor binding response to acute and chronic stress is increased in aging animals. Pharmacology. 1991; 42(4):181-7.
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  70. Ciraulo DA, Barnhill JG, Jaffe JH, Ciraulo AM, Tarmey MF. Intravenous pharmacokinetics of 2-hydroxyimipramine in alcoholics and normal controls. J Stud Alcohol. 1990 Jul; 51(4):366-72.
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  71. Ciraulo DA, Shader RI. Fluoxetine drug-drug interactions. II. J Clin Psychopharmacol. 1990 Jun; 10(3):213-7.
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  72. Ciraulo DA, Shader RI. Fluoxetine drug-drug interactions: I. Antidepressants and antipsychotics. J Clin Psychopharmacol. 1990 Feb; 10(1):48-50.
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  73. Ciraulo DA, Antal EJ, Smith RB, Olson DR, Goldberg DA, Rand EH, Raskin RB, Phillips JP, Shader RI, Greenblatt DJ. The relationship of alprazolam dose to steady-state plasma concentrations. J Clin Psychopharmacol. 1990 Feb; 10(1):27-32.
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  74. Baron DH, Sands BF, Ciraulo DA, Shader RI. The diagnosis and treatment of panic disorder in alcoholics: three cases. Am J Drug Alcohol Abuse. 1990; 16(3-4):287-95.
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  75. Ciraulo DA, Barnhill JG, Ciraulo AM, Greenblatt DJ, Shader RI. Parental alcoholism as a risk factor in benzodiazepine abuse: a pilot study. Am J Psychiatry. 1989 Oct; 146(10):1333-5.
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  76. Ciraulo DA. Can disulfiram (Antabuse) be safely co-administered with the monoamine oxidase inhibitor (MAOI) antidepressants? Despite the ability of the major metabolite of disulfiram (diethyldithiocarbamate) to inhibit the enzyme dopamine beta-hydroxylase and a report of the induction in rats of central motor disturbances, convulsions, and death following the co-administration of tranylcypromine, there appears to be surprisingly little in the literature that directly addresses this question. J Clin Psychopharmacol. 1989 Aug; 9(4):315-6.
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  77. Neafsey PJ, Boxenbaum H, Ciraulo DA, Fournier DJ. A Gompertz age-specific mortality rate model of aging, hormesis, and toxicity: dose-response studies. Drug Metab Rev. 1989; 20(1):111-50.
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  78. Neafsey PJ, Boxenbaum H, Ciraulo DA, Fournier DJ. A Gompertz age-specific mortality rate model of aging: modification by dietary restriction in rats. Drug Metab Rev. 1989; 21(2):351-65.
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  79. Ciraulo DA, Sands BF, Shader RI. Critical review of liability for benzodiazepine abuse among alcoholics. Am J Psychiatry. 1988 Dec; 145(12):1501-6.
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  80. Ciraulo DA, Barnhill JG, Greenblatt DJ, Shader RI, Ciraulo AM, Tarmey MF, Molloy MA, Foti ME. Abuse liability and clinical pharmacokinetics of alprazolam in alcoholic men. J Clin Psychiatry. 1988 Sep; 49(9):333-7.
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  81. Ciraulo DA, Barnhill JG, Jaffe JH. Clinical pharmacokinetics of imipramine and desipramine in alcoholics and normal volunteers. Clin Pharmacol Ther. 1988 May; 43(5):509-18.
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  82. Neafsey PJ, Boxenbaum H, Ciraulo DA, Fournier DJ. A Gompertz age-specific mortality rate model of aging, hormesis, and toxicity: fixed-dose studies. Drug Metab Rev. 1988; 19(3-4):369-401.
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  83. Ciraulo DA, Barnhill JG, Boxenbaum HG, Greenblatt DJ, Smith RB. Pharmacokinetics and clinical effects of alprazolam following single and multiple oral doses in patients with panic disorder. J Clin Pharmacol. 1986 Apr; 26(4):292-8.
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  84. Ciraulo DA, Barnhill J. Pharmacokinetic mechanisms of ethanol-psychotropic drug interactions. NIDA Res Monogr. 1986; 68:73-88.
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  85. Ciraulo DA, Barnhill J, Boxenbaum H. Pharmacokinetic interaction of disulfiram and antidepressants. Am J Psychiatry. 1985 Nov; 142(11):1373-4.
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  86. Ciraulo DA. Abuse potential of benzodiazepines. Bull N Y Acad Med. 1985 Oct; 61(8):728-41.
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  87. Boxenbaum H, Ciraulo D. Alcoholism and mortality kinetics. J Pharm Sci. 1984 Sep; 73(9):1191-5.
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  88. Khan A, Ciraulo DA, Nelson WH, Becker JT, Nies A, Jaffe JH. Dexamethasone suppression test in recently detoxified alcoholics: clinical implications. J Clin Psychopharmacol. 1984 Apr; 4(2):94-7.
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  89. Jaffe JH, Ciraulo DA, Nies A, Dixon RB, Monroe LL. Abuse potential of halazepam and of diazepam in patients recently treated for acute alcohol withdrawal. Clin Pharmacol Ther. 1983 Nov; 34(5):623-30.
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  90. Ciraulo DA, Alderson LM, Chapron DJ, Jaffe JH, Subbarao B, Kramer PA. Imipramine disposition in alcoholics. J Clin Psychopharmacol. 1982 Feb; 2(1):2-7.
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  91. Shader RI, Ciraulo DA, Greenblatt DJ, Harmatz JS. Steady-state plasma desmethyldiazepam during long-term clorazepate use: effects of antacids. Clin Pharmacol Ther. 1982 Feb; 31(2):180-3.
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  92. Divoll M, Greenblatt DJ, Ciraulo DA, Puri SK, Ho I, Shader RI. Clobazam kinetics: intrasubject variability and effect of food on adsorption. J Clin Pharmacol. 1982 Jan; 22(1):69-73.
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  93. Ciraulo DA, Jaffe JH. Tricyclic antidepressants in the treatment of depression associated with alcoholism. J Clin Psychopharmacol. 1981 May; 1(3):146-50.
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  94. Shader RI, Greenblatt DJ, Ciraulo DA, Divoll M, Harmatz JS, Georgotas A. Effect of age and sex on disposition of desmethyldiazepam formed from its precursor clorazepate. Psychopharmacology (Berl). 1981; 75(2):193-7.
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  95. Ratey JJ, Ciraulo DA, Shader RI. Lithium and marijuana. J Clin Psychopharmacol. 1981 Jan; 1(1):32-3.
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  96. Weiss KJ, Ciraulo DA, Shader RI. Physostigmine test in the rabbit syndrome and tardive dyskinesia. Am J Psychiatry. 1980 May; 137(5):627-8.
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  97. Ciraulo DA, Markovitz A. Myocardial infarction in pregnancy associated with a coronary artery thrombus. Arch Intern Med. 1979 Sep; 139(9):1046-7.
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  98. Shader RI, Ciraulo DA, Greenblatt DJ. Drug interactions involving psychotropic drugs. Psychosomatics. 1978 Nov; 19(11):671-3, 677-81.
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  99. Ciraulo D, Lind L, Salzman C, Pilon R, Elkins R. Sodium nitroprusside treatment of ECT-induced blood pressure elevations. Am J Psychiatry. 1978 Sep; 135(9):1105-6.
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  100. Greenblatt DJ, Gross PL, Harris J, Shader RI, Ciraulo DA. Fatal hyperthermia following haloperidol therapy of sedative-hypnotic withdrawal. J Clin Psychiatry. 1978 Aug; 39(8):673-5.
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  101. Shader RI, Elkins R, Ciraulo D, Salzman C. On guidelines for maximum dosages. Am J Psychiatry. 1978 Apr; 135(4):499-500.
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