Keywords
Last Name

Yoshiyuki Mochida, DDS, PhD

TitleClinical Assistant Professor
InstitutionBoston University Henry M. Goldman School of Dental Medicine
DepartmentMolecular & Cell Biology
Address700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
Phone(617) 638-4982
ORCID ORCID Icon0000-0002-2115-4303
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ohyama Y, Lin JH, Govitvattana N, Lin IP, Venkitapathi S, Alamoudi A, Husein D, An C, Hotta H, Kaku M, Mochida Y. FAM20A binds to and regulates FAM20C localization. Sci Rep. 2016; 6:27784. PMID: 27292199.
    View in: PubMed
  2. Jaha H, Husein D, Ohyama Y, Xu D, Suzuki S, Huang GT, Mochida Y. N-terminal Dentin Sialoprotein fragment induces type I collagen production and upregulates dentinogenesis marker expression in osteoblasts. Biochem Biophys Rep. 2016 Jun; 6:190-196. PMID: 27158678.
    View in: PubMed
  3. Badri MK, Zhang H, Ohyama Y, Venkitapathi S, Alamoudi A, Kamiya N, Takeda H, Ray M, Scott G, Tsuji T, Kunieda T, Mishina Y, Mochida Y. Expression of Evc2 in craniofacial tissues and craniofacial bone defects in Evc2 knockout mouse. Arch Oral Biol. 2016 Aug; 68:142-52. PMID: 27164562.
    View in: PubMed
  4. Badri MK, Zhang H, Ohyama Y, Venkitapathi S, Kamiya N, Takeda H, Ray M, Scott G, Tsuji T, Kunieda T, Mishina Y, Mochida Y. Ellis Van Creveld2 is Required for Postnatal Craniofacial Bone Development. Anat Rec (Hoboken). 2016 Aug; 299(8):1110-20. PMID: 27090777.
    View in: PubMed
  5. Zhang H, Takeda H, Tsuji T, Kamiya N, Rajderkar S, Louie K, Collier C, Scott G, Ray M, Mochida Y, Kaartinen V, Kunieda T, Mishina Y. Generation of Evc2/Limbin global and conditional KO mice and its roles during mineralized tissue formation. Genesis. 2015 Jul 28. PMID: 26219237.
    View in: PubMed
  6. Kaku M, Komatsu Y, Mochida Y, Yamauchi M, Mishina Y, Ko CC. Identification and characterization of neural crest-derived cells in adult periodontal ligament of mice. Arch Oral Biol. 2012 Dec; 57(12):1668-75. PMID: 22704955.
    View in: PubMed
  7. Ohyama Y, Katafuchi M, Almehmadi A, Venkitapathi S, Jaha H, Ehrenman J, Morcos J, Aljamaan R, Mochida Y. Modulation of matrix mineralization by Vwc2-like protein and its novel splicing isoforms. Biochem Biophys Res Commun. 2012 Feb 3; 418(1):12-6. PMID: 22209847.
    View in: PubMed
  8. Boushell LW, Kaku M, Mochida Y, Yamauchi M. Distribution and relative activity of matrix metalloproteinase-2 in human coronal dentin. Int J Oral Sci. 2011 Oct; 3(4):192-9. PMID: 22010577.
    View in: PubMed
  9. Mochida Y, Kaku M, Yoshida K, Katafuchi M, Atsawasuwan P, Yamauchi M. Podocan-like protein: a novel small leucine-rich repeat matrix protein in bone. Biochem Biophys Res Commun. 2011 Jul 1; 410(2):333-8. PMID: 21672516.
    View in: PubMed
  10. Atsawasuwan P, Mochida Y, Katafuchi M, Tokutomi K, Mocanu V, Parker CE, Yamauchi M. A novel proteolytic processing of prolysyl oxidase. Connect Tissue Res. 2011; 52(6):479-86. PMID: 21591931.
    View in: PubMed
  11. Miguez PA, Terajima M, Nagaoka H, Mochida Y, Yamauchi M. Role of glycosaminoglycans of biglycan in BMP-2 signaling. Biochem Biophys Res Commun. 2011 Feb 11; 405(2):262-6. PMID: 21219861.
    View in: PubMed
  12. Kamiya N, Kobayashi T, Mochida Y, Yu PB, Yamauchi M, Kronenberg HM, Mishina Y. Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. J Bone Miner Res. 2010 Feb; 25(2):200-10. PMID: 19874086.
    View in: PubMed
  13. Kamiya N, Ye L, Kobayashi T, Lucas DJ, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y. Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. J Bone Miner Res. 2008 Dec; 23(12):2007-17. PMID: 18684091.
    View in: PubMed
  14. Mochida Y, Parisuthiman D, Pornprasertsuk-Damrongsri S, Atsawasuwan P, Sricholpech M, Boskey AL, Yamauchi M. Decorin modulates collagen matrix assembly and mineralization. Matrix Biol. 2009 Jan; 28(1):44-52. PMID: 19049867.
    View in: PubMed
  15. Nagaoka H, Mochida Y, Atsawasuwan P, Kaku M, Kondoh T, Yamauchi M. 1,25(OH)2D3 regulates collagen quality in an osteoblastic cell culture system. Biochem Biophys Res Commun. 2008 Dec 12; 377(2):674-8. PMID: 18930711.
    View in: PubMed
  16. Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y. BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov; 135(22):3801-11. PMID: 18927151.
    View in: PubMed
  17. Atsawasuwan P, Mochida Y, Katafuchi M, Kaku M, Fong KS, Csiszar K, Yamauchi M. Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity. J Biol Chem. 2008 Dec 5; 283(49):34229-40. PMID: 18835815.
    View in: PubMed
  18. Boushell LW, Kaku M, Mochida Y, Bagnell R, Yamauchi M. Immunohistochemical localization of matrixmetalloproteinase-2 in human coronal dentin. Arch Oral Biol. 2008 Feb; 53(2):109-16. PMID: 18001692.
    View in: PubMed
  19. Kaku M, Mochida Y, Atsawasuwan P, Parisuthiman D, Yamauchi M. Post-translational modifications of collagen upon BMP-induced osteoblast differentiation. Biochem Biophys Res Commun. 2007 Aug 3; 359(3):463-8. PMID: 17553463.
    View in: PubMed
  20. Mochida Y, Parisuthiman D, Kaku M, Hanai J, Sukhatme VP, Yamauchi M. Nephrocan, a novel member of the small leucine-rich repeat protein family, is an inhibitor of transforming growth factor-beta signaling. J Biol Chem. 2006 Nov 24; 281(47):36044-51. PMID: 16990280.
    View in: PubMed
  21. Mochida Y, Parisuthiman D, Yamauchi M. Biglycan is a positive modulator of BMP-2 induced osteoblast differentiation. Adv Exp Med Biol. 2006; 585:101-13. PMID: 17120779.
    View in: PubMed
  22. Parisuthiman D, Mochida Y, Duarte WR, Yamauchi M. Biglycan modulates osteoblast differentiation and matrix mineralization. J Bone Miner Res. 2005 Oct; 20(10):1878-86. PMID: 16160746.
    View in: PubMed
  23. Atsawasuwan P, Mochida Y, Parisuthiman D, Yamauchi M. Expression of lysyl oxidase isoforms in MC3T3-E1 osteoblastic cells. Biochem Biophys Res Commun. 2005 Feb 25; 327(4):1042-6. PMID: 15652501.
    View in: PubMed
  24. Pornprasertsuk S, Duarte WR, Mochida Y, Yamauchi M. Overexpression of lysyl hydroxylase-2b leads to defective collagen fibrillogenesis and matrix mineralization. J Bone Miner Res. 2005 Jan; 20(1):81-7. PMID: 15619673.
    View in: PubMed
  25. Endo Y, Uzawa K, Mochida Y, Shiiba M, Bukawa H, Yokoe H, Tanzawa H. Sarcoendoplasmic reticulum Ca(2+) ATPase type 2 downregulated in human oral squamous cell carcinoma. Int J Cancer. 2004 Jun 10; 110(2):225-31. PMID: 15069686.
    View in: PubMed
  26. Pornprasertsuk S, Duarte WR, Mochida Y, Yamauchi M. Lysyl hydroxylase-2b directs collagen cross-linking pathways in MC3T3-E1 cells. J Bone Miner Res. 2004 Aug; 19(8):1349-55. PMID: 15231023.
    View in: PubMed
  27. Ono K, Uzawa K, Nakatsuru M, Shiiba M, Mochida Y, Tada A, Bukawa H, Miyakawa A, Yokoe H, Tanzawa H. Down-regulation of FEZ1/LZTS1 gene with frequent loss of heterozygosity in oral squamous cell carcinomas. Int J Oncol. 2003 Aug; 23(2):297-302. PMID: 12851677.
    View in: PubMed
  28. Uzawa K, Yeowell HN, Yamamoto K, Mochida Y, Tanzawa H, Yamauchi M. Lysine hydroxylation of collagen in a fibroblast cell culture system. Biochem Biophys Res Commun. 2003 Jun 6; 305(3):484-7. PMID: 12763018.
    View in: PubMed
  29. Mochida Y, Duarte WR, Tanzawa H, Paschalis EP, Yamauchi M. Decorin modulates matrix mineralization in vitro. Biochem Biophys Res Commun. 2003 May 23; 305(1):6-9. PMID: 12732188.
    View in: PubMed
  30. Endo Y, Uzawa K, Mochida Y, Nakatsuru M, Shiiba M, Yokoe H, Yamauchi M, Tanzawa H. Differential distribution of glycosaminoglycans in human cementifying fibroma and fibro-osseous lesions. Oral Dis. 2003 Mar; 9(2):73-6. PMID: 12657032.
    View in: PubMed
  31. Yamashita Y, Miyakawa A, Mochida Y, Aisaki K, Yama M, Shiiba M, Watanabe T, Yokoe H, Uzawa K, Imai Y, Tanzawa H. Genetic aberration on chromosome 10 in human oral squamous cell carcinoma. Int J Oncol. 2002 Mar; 20(3):595-8. PMID: 11836574.
    View in: PubMed
  32. Mochida Y, Takeda K, Saitoh M, Nishitoh H, Amagasa T, Ninomiya-Tsuji J, Matsumoto K, Ichijo H. ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction. J Biol Chem. 2000 Oct 20; 275(42):32747-52. PMID: 10921914.
    View in: PubMed
  33. Hatai T, Matsuzawa A, Inoshita S, Mochida Y, Kuroda T, Sakamaki K, Kuida K, Yonehara S, Ichijo H, Takeda K. Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation. J Biol Chem. 2000 Aug 25; 275(34):26576-81. PMID: 10849426.
    View in: PubMed
  34. Mochida Y. [Functional analysis of apoptosis signal-regulating kinase 1 (ASK 1)-binding proteins]. Kokubyo Gakkai Zasshi. 2000 Jun; 67(2):182-92. PMID: 10921242.
    View in: PubMed
  35. Nishitoh H, Saitoh M, Mochida Y, Takeda K, Nakano H, Rothe M, Miyazono K, Ichijo H. ASK1 is essential for JNK/SAPK activation by TRAF2. Mol Cell. 1998 Sep; 2(3):389-95. PMID: 9774977.
    View in: PubMed
  36. Takeda K, Ichijo H, Fujii M, Mochida Y, Saitoh M, Nishitoh H, Sampath TK, Miyazono K. Identification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA. J Biol Chem. 1998 Jul 3; 273(27):17079-85. PMID: 9642273.
    View in: PubMed
  37. Tsuchida Y, Mochida Y, Kamii Y, Honna T, Saeki M, Hata J, Yokoyama T, Sasaki F, Nishiura M, Takeda K, et al. Determination of plasma total renin level by RIA with a monoclonal antibody: value as a marker for nephroblastoma. J Pediatr Surg. 1990 Oct; 25(10):1092-4. PMID: 2175785.
    View in: PubMed
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