Keywords
Last Name

Carl Franzblau, PhD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentBiochemistry
Address72 E. Concord St Building A
Boston MA 02118
Phone(617) 638-5320
ORCID ORCID Icon0000-0001-9248-6324
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

 Awards and Honors

Start-EndDescription
1986Boston University: Metcaf Cup and Prize in Teaching
2009A Einstein College of Medicine: Distinguished PhD Alumnus Award
1988Roger Williams Univ: Honary Doctor of Science
1966-1970American Heart Association: Established Investigator
1988Czech National Acad: G Mendel award
1977Boston University: AOA Faculty Election for Teaching
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Janardhan V, Wolf PA, Kase CS, Massaro JM, D'Agostino RB, Franzblau C, Wilson PW. Anticardiolipin antibodies and risk of ischemic stroke and transient ischemic attack: the Framingham cohort and offspring study. Stroke. 2004 Mar; 35(3):736-41. PMID: 14764933.
    View in: PubMed
  2. Rost NS, Wolf PA, Kase CS, Kelly-Hayes M, Silbershatz H, Massaro JM, D'Agostino RB, Franzblau C, Wilson PW. Plasma concentration of C-reactive protein and risk of ischemic stroke and transient ischemic attack: the Framingham study. Stroke. 2001 Nov; 32(11):2575-9. PMID: 11692019.
    View in: PubMed
  3. Hsiao H, Stone PJ, Toselli P, Rosenbloom J, Franzblau C, Schreiber BM. The role of the carboxy terminus of tropoelastin in its assembly into the elastic fiber. Connect Tissue Res. 1999; 40(2):83-95. PMID: 10761633.
    View in: PubMed
  4. Stone PJ, Lucey EC, Snider GL, Franzblau C. Distribution of elastin in hamsters and the turnover rates of different elastin pools. Proc Soc Exp Biol Med. 1997 May; 215(1):94-101. PMID: 9142143.
    View in: PubMed
  5. Bhatia S, Bergethon PR, Blease S, Kemper T, Rosiello A, Zimbardi GP, Franzblau C, Spatz EL. A synthetic dural prosthesis constructed from hydroxyethylmethacrylate hydrogels. J Neurosurg. 1995 Nov; 83(5):897-902. PMID: 7472561.
    View in: PubMed
  6. Stone PJ, Franzblau C. Increase in urinary desmosine and pyridinoline during postpartum involution of the uterus in humans. Proc Soc Exp Biol Med. 1995 Oct; 210(1):39-42. PMID: 7675796.
    View in: PubMed
  7. Stone PJ, Konstan MW, Berger M, Dorkin HL, Franzblau C, Snider GL. Elastin and collagen degradation products in urine of patients with cystic fibrosis. Am J Respir Crit Care Med. 1995 Jul; 152(1):157-62. PMID: 7599816.
    View in: PubMed
  8. Stone PJ, Korn JH, North H, Lally EV, Miller LC, Tucker LB, Strongwater S, Snider GL, Franzblau C. Cross-linked elastin and collagen degradation products in the urine of patients with scleroderma. Arthritis Rheum. 1995 Apr; 38(4):517-24. PMID: 7718005.
    View in: PubMed
  9. Stone PJ, Gottlieb DJ, O'Connor GT, Ciccolella DE, Breuer R, Bryan-Rhadfi J, Shaw HA, Franzblau C, Snider GL. Elastin and collagen degradation products in urine of smokers with and without chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1995 Apr; 151(4):952-9. PMID: 7697272.
    View in: PubMed
  10. Stone PJ, Morris TA, Franzblau C, Snider GL. Preliminary evidence that augmentation therapy diminishes degradation of cross-linked elastin in alpha-1-antitrypsin-deficient humans. Respiration. 1995; 62(2):76-9. PMID: 7784713.
    View in: PubMed
  11. Schreiber BM, Jones HV, Franzblau C. Apolipoprotein E expression in aortic smooth muscle cells: the effect of beta VLDL. J Lipid Res. 1994 Jul; 35(7):1177-86. PMID: 7964179.
    View in: PubMed
  12. Trinkaus-Randall V, Banwatt R, Wu XY, Leibowitz HM, Franzblau C. Effect of pretreating porous webs on stromal fibroplasia in vivo. J Biomed Mater Res. 1994 Feb; 28(2):195-202. PMID: 8207031.
    View in: PubMed
  13. Stone PJ, Lucey EC, Snider GL, Franzblau C. Effect of diet on urinary excretion of desmosine and hydroxylysyl pyridinoline. Am J Respir Crit Care Med. 1994 Jan; 149(1):174-7. PMID: 8111578.
    View in: PubMed
  14. Aqrabawi J, Schilder H, Toselli P, Franzblau C. Biochemical and histochemical analysis of the enzyme arylsulfatase in human lesions of endodontic origin. J Endod. 1993 Jul; 19(7):335-8. PMID: 8245755.
    View in: PubMed
  15. Stone PJ, Lucey EC, Breuer R, Christensen TG, Zaslow MC, Clark RA, Franzblau C, Snider GL. Oxidants from neutrophil myeloperoxidase do not enhance elastase-induced emphysema in the hamster. Respiration. 1993; 60(3):137-43. PMID: 8210717.
    View in: PubMed
  16. Hospelhorn AC, Martin BM, Franzblau C. Type IV collagen synthesis and accumulation in neonatal rat aortic smooth muscle cell cultures. Matrix. 1992 Nov; 12(5):352-61. PMID: 1484503.
    View in: PubMed
  17. Stone PJ, Bryan-Rhadfi J, Shaw HA, Franzblau C. Isolation of hydroxylysyl pyridinoline, a mature collagen crosslink from neonatal rat aorta smooth muscle cell cultures. Matrix. 1992 Nov; 12(5):381-7. PMID: 1484505.
    View in: PubMed
  18. Schreiber BM, Jones HV, Toselli P, Franzblau C. Long-term treatment of neonatal aortic smooth muscle cells with beta VLDL induces cholesterol accumulation. Atherosclerosis. 1992 Aug; 95(2-3):201-10. PMID: 1418093.
    View in: PubMed
  19. Toselli P, Faris B, Sassoon D, Jackson BA, Franzblau C. In-situ hybridization of tropoelastin mRNA during the development of the multilayered neonatal rat aortic smooth muscle cell culture. Matrix. 1992 Aug; 12(4):321-32. PMID: 1435516.
    View in: PubMed
  20. Faris B, Tan OT, Toselli P, Franzblau C. Long-term neonatal rat aortic smooth muscle cell cultures: a model for the tunica media of a blood vessel. Matrix. 1992 Jun; 12(3):185-8. PMID: 1406452.
    View in: PubMed
  21. Wolfe BL, Schreiber BM, Bryan-Rhadfi J, Stone PJ, Franzblau C. Alterations of tropoelastin biosynthesis by elastase damage to smooth muscle cell matrices. Matrix. 1992 Apr; 12(2):163-71. PMID: 1603039.
    View in: PubMed
  22. Martin BM, Ritchie AR, Toselli P, Franzblau C. Elastin synthesis and accumulation in irradiated smooth muscle cell cultures. Connect Tissue Res. 1992; 28(3):181-9. PMID: 1468206.
    View in: PubMed
  23. Trinkaus-Randall V, Banwatt R, Capecchi J, Leibowitz HM, Franzblau C. In vivo fibroplasia of a porous polymer in the cornea. Invest Ophthalmol Vis Sci. 1991 Dec; 32(13):3245-51. PMID: 1748554.
    View in: PubMed
  24. Faris B, Jackson LE, Schreiber BM, Martin BM, Jones HV, Franzblau C. A controlled precursor add-back model of elastogenesis in smooth muscle cell cultures. Matrix. 1991 Nov; 11(5):367-72. PMID: 1811167.
    View in: PubMed
  25. Jackson LE, Faris B, Martin BM, Jones HV, Rich CB, Foster JA, Franzblau C. The effect of beta-aminopropionitrile on elastin gene expression in smooth muscle cell cultures. Biochem Biophys Res Commun. 1991 Sep 16; 179(2):939-44. PMID: 1680324.
    View in: PubMed
  26. Stone PJ, Bryan-Rhadfi J, Lucey EC, Ciccolella DE, Crombie G, Faris B, Snider GL, Franzblau C. Measurement of urinary desmosine by isotope dilution and high performance liquid chromatography. Correlation between elastase-induced air-space enlargement in the hamster and elevation of urinary desmosine. Am Rev Respir Dis. 1991 Aug; 144(2):284-90. PMID: 1859049.
    View in: PubMed
  27. Tan OT, Faris B, Franzblau C. Aortic elastin fluorescence afterin vivo labeling with Congo red. J Fluoresc. 1991 Jun; 1(2):147-51. PMID: 24242965.
    View in: PubMed
  28. Berk JL, Franzblau C, Goldstein RH. Recombinant interleukin-1 beta inhibits elastin formation by a neonatal rat lung fibroblast subtype. J Biol Chem. 1991 Feb 15; 266(5):3192-7. PMID: 1993692.
    View in: PubMed
  29. Stone PJ, Lucey EC, Bryan-Rhadfi J, Snider GL, Franzblau C. Isolation of urinary desmosine by HPLC, amino acid analysis, and quantification by isotope dilution. Ann N Y Acad Sci. 1991; 624:355-7. PMID: 2064245.
    View in: PubMed
  30. Kaufmann J, Jorgensen RW, Martin BM, Franzblau C. Monocyte activation by smooth muscle cell-derived matrices. Atherosclerosis. 1990 Dec; 85(2-3):113-25. PMID: 2102075.
    View in: PubMed
  31. Trinkaus-Randall V, Capecchi J, Sammon L, Gibbons D, Leibowitz HM, Franzblau C. In vitro evaluation of fibroplasia in a porous polymer. Invest Ophthalmol Vis Sci. 1990 Jul; 31(7):1321-6. PMID: 2365562.
    View in: PubMed
  32. Trinkaus-Randall V, Newton AW, Franzblau C. The synthesis and role of integrin in corneal epithelial cells in culture. Invest Ophthalmol Vis Sci. 1990 Mar 1; 31(3):440-7. PMID: 2108096.
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  33. Sipe JD, Gonnerman WA, Loose LD, Knapschaefer G, Xie WJ, Franzblau C. Direct binding enzyme-linked immunosorbent assay (ELISA) for serum amyloid A (SAA). J Immunol Methods. 1989 Dec 20; 125(1-2):125-35. PMID: 2607146.
    View in: PubMed
  34. Franzblau C, Pratt CA, Faris B, Colannino NM, Offner GD, Mogayzel PJ, Troxler RF. Role of tropoelastin fragmentation in elastogenesis in rat smooth muscle cells. J Biol Chem. 1989 Sep 5; 264(25):15115-9. PMID: 2768256.
    View in: PubMed
  35. Bergethon PR, Mogayzel PJ, Franzblau C. Effect of the reducing environment on the accumulation of elastin and collagen in cultured smooth-muscle cells. Biochem J. 1989 Feb 15; 258(1):279-84. PMID: 2930513.
    View in: PubMed
  36. Bergethon PR, Trinkaus-Randall V, Franzblau C. Modified hydroxyethylmethacrylate hydrogels as a modelling tool for the study of cell-substratum interactions. J Cell Sci. 1989 Jan; 92 ( Pt 1):111-21. PMID: 2777911.
    View in: PubMed
  37. Trinkaus-Randall V, Newton A, Franzblau C. Influence of substratum on corneal epithelial cell growth and protein synthesis. Invest Ophthalmol Vis Sci. 1988 Dec; 29(12):1800-9. PMID: 3192369.
    View in: PubMed
  38. Stone PJ, Morris SM, Martin BM, McMahon MP, Faris B, Franzblau C. Repair of protease-damaged elastin in neonatal rat aortic smooth muscle cell cultures. J Clin Invest. 1988 Nov; 82(5):1644-54. PMID: 3141480.
    View in: PubMed
  39. Hospelhorn AC, Faris B, Mogayzel PJ, Tan OT, Franzblau C. Congo red binding of elastin in aortic smooth muscle cell cultures. J Histochem Cytochem. 1988 Oct; 36(10):1353-8. PMID: 3418110.
    View in: PubMed
  40. Hussain MM, Bucher NL, Faris B, Franzblau C, Zannis VI. Tissue-specific posttranslational modification of rat apoE. Synthesis of sialated apoE forms by neonatal rat aortic smooth muscle cells. J Lipid Res. 1988 Jul; 29(7):915-23. PMID: 3411250.
    View in: PubMed
  41. Barone LM, Wolfe BL, Faris B, Franzblau C. Elastin mRNA levels and insoluble elastin accumulation in neonatal rat smooth muscle cell cultures. Biochemistry. 1988 May 3; 27(9):3175-82. PMID: 3390428.
    View in: PubMed
  42. Snider GL, Lucey EC, Faris B, Jung-Legg Y, Stone PJ, Franzblau C. Cadmium-chloride-induced air-space enlargement with interstitial pulmonary fibrosis is not associated with destruction of lung elastin. Implications for the pathogenesis of human emphysema. Am Rev Respir Dis. 1988 Apr; 137(4):918-23. PMID: 3355000.
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  43. Trinkaus-Randall V, Capecchi J, Newton A, Vadasz A, Leibowitz H, Franzblau C. Development of a biopolymeric keratoprosthetic material. Evaluation in vitro and in vivo. Invest Ophthalmol Vis Sci. 1988 Mar; 29(3):393-400. PMID: 3343096.
    View in: PubMed
  44. Trinkaus-Randall V, Newton AW, Gipson IK, Franzblau C. Carbohydrate moieties of the basal lamina: their role in attachment and spreading of basal corneal epithelial cells. Cell Tissue Res. 1988 Feb; 251(2):315-23. PMID: 3345547.
    View in: PubMed
  45. Weintraub LR, Goral A, Grasso J, Franzblau C, Sullivan A, Sullivan S. Collagen biosynthesis in iron overload. Ann N Y Acad Sci. 1988; 526:179-84. PMID: 2839074.
    View in: PubMed
  46. Stone PJ, Lucey EC, Calore JD, McMahon MP, Snider GL, Franzblau C. Defenses of the hamster lung against human neutrophil and porcine pancreatic elastase. Respiration. 1988; 54(1):1-15. PMID: 2469116.
    View in: PubMed
  47. Ohishi H, Hess D, Kosakai M, Schmid K, Hausmann J, Mogayzel PJ, Faris B, Franzblau C. Glycosaminoglycan content in neonatal rat aortic smooth muscle cell cultures. Atherosclerosis. 1988 Jan; 69(1):61-8. PMID: 3128301.
    View in: PubMed
  48. Schreiber BM, Martin BM, Hollander W, Franzblau C. beta-VLDL-induced alterations in growth potentiating activity produced by mononuclear phagocytes. Atherosclerosis. 1988 Jan; 69(1):69-79. PMID: 3355608.
    View in: PubMed
  49. Stone PJ, McMahon MP, Morris SM, Calore JD, Franzblau C. Elastin in a neonatal rat smooth muscle cell culture has greatly decreased susceptibility to proteolysis by human neutrophil elastase. An in vitro model of elastolytic injury. In Vitro Cell Dev Biol. 1987 Oct; 23(10):663-76. PMID: 3667486.
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  50. Pothoulakis C, Triadafilopoulos G, Clark M, Franzblau C, LaMont JT. Clostridium difficile cytotoxin inhibits protein synthesis in fibroblasts and intestinal mucosa. Gastroenterology. 1986 Nov; 91(5):1147-53. PMID: 3758606.
    View in: PubMed
  51. Faris B, Toselli P, Kispert J, Wolfe BL, Pratt CA, Mogayzel PJ, Franzblau C. Elastase effect on the extracellular matrix of rat aortic smooth muscle cells in culture. Exp Mol Pathol. 1986 Oct; 45(2):105-17. PMID: 3639821.
    View in: PubMed
  52. Goldstein RH, Sakowski S, Meeker D, Franzblau C, Polgar P. The effect of prostaglandin E2 (PGE2) on amino acid uptake and protein formation by lung fibroblasts. J Biol Chem. 1986 Jul 5; 261(19):8734-7. PMID: 3459727.
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  53. Stepp MA, Kindy MS, Franzblau C, Sonenshein GE. Complex regulation of collagen gene expression in cultured bovine aortic smooth muscle cells. J Biol Chem. 1986 May 15; 261(14):6542-7. PMID: 3700407.
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  54. Lichtenstein AH, Walewski J, Brecher P, Franzblau C, Faris B, Chobanian AV. Phospholipid methylation in rabbit aorta. Arch Biochem Biophys. 1986 Feb 15; 245(1):187-95. PMID: 3947098.
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  55. Pothoulakis C, Barone LM, Ely R, Faris B, Clark ME, Franzblau C, LaMont JT. Purification and properties of Clostridium difficile cytotoxin B. J Biol Chem. 1986 Jan 25; 261(3):1316-21. PMID: 3944088.
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  56. Cathcart ES, Hayes KC, Gonnerman WA, Lazzari AA, Franzblau C. Experimental arthritis in a nonhuman primate. I. Induction by bovine type II collagen. Lab Invest. 1986 Jan; 54(1):26-31. PMID: 3941539.
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  57. McMahon MP, Faris B, Wolfe BL, Brown KE, Pratt CA, Toselli P, Franzblau C. Aging effects on the elastin composition in the extracellular matrix of cultured rat aortic smooth muscle cells. In Vitro Cell Dev Biol. 1985 Dec; 21(12):674-80. PMID: 3908442.
    View in: PubMed
  58. Chipman SD, Faris B, Barone LM, Pratt CA, Franzblau C. Processing of soluble elastin in cultured neonatal rat smooth muscle cells. J Biol Chem. 1985 Oct 15; 260(23):12780-5. PMID: 4044609.
    View in: PubMed
  59. Leslie CA, Gonnerman WA, Ullman MD, Hayes KC, Franzblau C, Cathcart ES. Dietary fish oil modulates macrophage fatty acids and decreases arthritis susceptibility in mice. J Exp Med. 1985 Oct 1; 162(4):1336-49. PMID: 3930652.
    View in: PubMed
  60. Connelly CM, Vogel WM, Wiegner AW, Osmers EL, Bing OH, Kloner RA, Dunn-Lanchantin DM, Franzblau C, Apstein CS. Effects of reperfusion after coronary artery occlusion on post-infarction scar tissue. Circ Res. 1985 Oct; 57(4):562-77. PMID: 4042284.
    View in: PubMed
  61. Lucey EC, Stone PJ, Breuer R, Christensen TG, Calore JD, Catanese A, Franzblau C, Snider GL. Effect of combined human neutrophil cathepsin G and elastase on induction of secretory cell metaplasia and emphysema in hamsters, with in vitro observations on elastolysis by these enzymes. Am Rev Respir Dis. 1985 Aug; 132(2):362-6. PMID: 3849280.
    View in: PubMed
  62. Barone LM, Faris B, Chipman SD, Toselli P, Oakes BW, Franzblau C. Alteration of the extracellular matrix of smooth muscle cells by ascorbate treatment. Biochim Biophys Acta. 1985 Jun 18; 840(2):245-54. PMID: 2859894.
    View in: PubMed
  63. Zaslow MC, Clark RA, Stone PJ, Calore J, Snider GL, Franzblau C. Myeloperoxidase-induced inactivation of alpha 1-antiprotease in hamsters. J Lab Clin Med. 1985 Feb; 105(2):178-84. PMID: 2982979.
    View in: PubMed
  64. Weintraub LR, Goral A, Grasso J, Franzblau C, Sullivan A, Sullivan S. Pathogenesis of hepatic fibrosis in experimental iron overload. Br J Haematol. 1985 Feb; 59(2):321-31. PMID: 2982390.
    View in: PubMed
  65. Hu CL, Toselli P, Franzblau C. Synthesis and turnover of protein-bound Nt-methylhistidine in cultured vascular smooth muscle cells. Surv Synth Pathol Res. 1985; 4(5-6):380-8. PMID: 3837929.
    View in: PubMed
  66. Mogayzel PJ, Faris B, Ely R, Franzblau C. A comparison of cultured aortic smooth muscle cells from different sources: are they all the same? Surv Synth Pathol Res. 1985; 4(5-6):374-9. PMID: 2875512.
    View in: PubMed
  67. Binder R, Stone PJ, Calore JD, Dunn DM, Snider GL, Franzblau C, Valeri CR. Serum antielastase and neutrophil elastase levels in PiM phenotype cigarette smokers with airflow obstruction. Respiration. 1985; 47(4):267-77. PMID: 2409573.
    View in: PubMed
  68. McGowan SE, Stone PJ, Snider GL, Franzblau C. Alveolar macrophage modulation of proteolysis by neutrophil elastase in extracellular matrix. Am Rev Respir Dis. 1984 Nov; 130(5):734-9. PMID: 6568097.
    View in: PubMed
  69. Gerstenfeld L, Beldekas JC, Sonenshein GE, Franzblau C. Processing of procollagen types III and I in cultured bovine smooth muscle cells. J Biol Chem. 1984 Jul 25; 259(14):9158-62. PMID: 6746644.
    View in: PubMed
  70. Marti T, Kosen PA, Honory K, Franzblau C, Schmid K, Van Halbeek H, Gerwig GJ, Vliegenthart JF. The structure of the carbohydrate units of the carboxyl-terminal peptide of procollagen as elucidated by 500 MHz 1H-NMR spectroscopy. Biochim Biophys Acta. 1984 Jun 29; 799(3):305-12. PMID: 6733151.
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  71. Hollander W, Colombo M, Faris B, Franzblau C, Schmid K, Wernli M, Bernasconi U. Changes in the connective tissue proteins, glycosaminoglycans and calcium in the arteries of the cynomolgus monkey during atherosclerotic induction and regression. Atherosclerosis. 1984 Apr; 51(1):89-108. PMID: 6721905.
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  72. Toselli P, Faris B, Oliver P, Franzblau C. Ultrastructural studies of attachment site formation in aortic smooth muscle cells cultured on collagen-hydroxyethylmethacrylate hydrogels. J Ultrastruct Res. 1984 Mar; 86(3):252-61. PMID: 6544863.
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  73. Faris B, Ferrera R, Toselli P, Nambu J, Gonnerman WA, Franzblau C. Effect of varying amounts of ascorbate on collagen, elastin and lysyl oxidase synthesis in aortic smooth muscle cell cultures. Biochim Biophys Acta. 1984 Jan 24; 797(1):71-5. PMID: 6140957.
    View in: PubMed
  74. Snider GL, Lucey EC, Christensen TG, Stone PJ, Calore JD, Catanese A, Franzblau C. Emphysema and bronchial secretory cell metaplasia induced in hamsters by human neutrophil products. Am Rev Respir Dis. 1984 Jan; 129(1):155-60. PMID: 6561016.
    View in: PubMed
  75. Toselli P, Mogayzel PJ, Faris B, Ferrera R, Franzblau C. Mammalian cell growth on collagen-hydrogels. Scan Electron Microsc. 1984; (Pt 3):1301-12. PMID: 6505615.
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  76. Wedel N, Toselli P, Pothoulakis C, Faris B, Oliver P, Franzblau C, LaMont T. Ultrastructural effects of Clostridium difficile toxin B on smooth muscle cells and fibroblasts. Exp Cell Res. 1983 Oct 15; 148(2):413-22. PMID: 6628564.
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  77. Gerstenfeld L, Beldekas JC, Franzblau C, Sonenshein GE. Cell-free translation of calf type III collagen. Effect of magnesium on ribosome movement during elongation. J Biol Chem. 1983 Oct 10; 258(19):12058-63. PMID: 6619153.
    View in: PubMed
  78. Stone PJ, Calore JD, McGowan SE, Bernardo J, Snider GL, Franzblau C. Functional alpha 1-protease inhibitor in the lower respiratory tract of cigarette smokers is not decreased. Science. 1983 Sep 16; 221(4616):1187-9. PMID: 6612333.
    View in: PubMed
  79. Zaslow MC, Clark RA, Stone PJ, Calore JD, Snider GL, Franzblau C. Human neutrophil elastase does not bind to alpha 1-protease inhibitor that has been exposed to activated human neutrophils. Am Rev Respir Dis. 1983 Sep; 128(3):434-9. PMID: 6311062.
    View in: PubMed
  80. Karlinsky J, Fredette J, Davidovits G, Catanese A, Snider R, Faris B, Snider GL, Franzblau C. The balance of lung connective tissue elements in elastase-induced emphysema. J Lab Clin Med. 1983 Aug; 102(2):151-62. PMID: 6553073.
    View in: PubMed
  81. Toselli P, Faris B, Oliver P, Wedel N, Franzblau C. Preservation of ultrastructure of cells cultured on protein-hydroxyethylmethacrylate hydrogels. J Ultrastruct Res. 1983 May; 83(2):220-31. PMID: 6864863.
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  82. Stone PJ, Calore JD, McGowan SE, Bernardo J, Snider GL, Franzblau C. Smokers do not have less functional alpha 1-protease inhibitor in their lower respiratory tracts than nonsmokers. Chest. 1983 May; 83(5 Suppl):65S-66S. PMID: 6601572.
    View in: PubMed
  83. Morris SM, Stone PJ, Snider GL, Albright JT, Franzblau C. Autoradiographic study of 3H-methylated elastase in hamster lungs. Anat Rec. 1983 May; 206(1):31-42. PMID: 6554048.
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  84. McGowan SE, Stone PJ, Calore JD, Snider GL, Franzblau C. The fate of neutrophil elastase incorporated by human alveolar macrophages. Am Rev Respir Dis. 1983 Apr; 127(4):449-55. PMID: 6551160.
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  85. Faris B, Mozzicato P, Mogayzel PJ, Ferrera R, Gerstenfeld LC, Glembourtt M, Makarski JS, Haudenschild CC, Franzblau C. Effect of protein-hydroxyethylmethacrylate hydrogels on cultured endothelial cells. Exp Cell Res. 1983 Jan; 143(1):15-25. PMID: 6825716.
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  86. Skinner M, Schneller SI, Connors LH, Kagan HM, Stone PJ, Shirahama T, Sipe JD, O'Connor C, Calore JD, Franzblau C, et al. Observations on the amyloid-degrading activity of serum and its relationship to human neutrophil elastase. Trans Assoc Am Physicians. 1983; 96:437-43. PMID: 6437036.
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  87. Stone PJ, Calore JD, Franzblau C. Release of human neutrophil elastase from alpha 2-macroglobulin complexes containing human neutrophil elastase. Ann N Y Acad Sci. 1983; 421:398-400. PMID: 6202211.
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  88. Tracey KJ, Mutkoski R, Lopez JA, Franzblau W, Franzblau C. Radioimmunoassay for methotrexate using hydroxyethylmethacrylate hydrogel. Cancer Chemother Pharmacol. 1983; 10(2):96-9. PMID: 6831631.
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  89. Imberman M, Oppenheim F, Franzblau C. The appearance of free hydroxyproline as the major product of degradation of newly synthesized collagen in cell culture. Biochim Biophys Acta. 1982 Dec 17; 719(3):480-7. PMID: 7150655.
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  90. Mozzicato P, Faris B, Hollander W, Franzblau C, Schmid K. A method to evaluate the biosynthesis of glycosaminoglycans by the aorta of Cynomolgus monkey. Atherosclerosis. 1982 Dec; 45(3):359-63. PMID: 6818978.
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  91. Goldstein RH, Miller K, Glassroth J, Linscott R, Snider GL, Franzblau C, Polgar P. Influence of asbestos fibers on collagen and prostaglandin production in fibroblast and macrophage co-cultures. J Lab Clin Med. 1982 Nov; 100(5):778-85. PMID: 7130833.
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  92. Ferrera R, Faris B, Mogayzel PJ, Gonnerman WA, Franzblau C. A micromethod for the purification of lysyl oxidase. Anal Biochem. 1982 Nov 1; 126(2):312-7. PMID: 6130722.
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  93. Beldekas JC, Gerstenfeld L, Sonenshein GE, Franzblau C. Cell density and estradiol modulation of procollagen type III in cultured calf smooth muscle cells. J Biol Chem. 1982 Oct 25; 257(20):12252-6. PMID: 7118942.
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  94. Kosen PA, Franzblau C. Kinetics of reduction of the intersubunit disulfides of the carboxyl propeptide of type I procollagen. Biochemistry. 1982 Aug 31; 21(18):4278-84. PMID: 7126545.
    View in: PubMed
  95. Dunn DM, Franzblau C. Effects of ascorbate on insoluble elastin accumulation and cross-link formation in rabbit pulmonary artery smooth muscle cultures. Biochemistry. 1982 Aug 31; 21(18):4195-202. PMID: 6812621.
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  96. Stone PJ, Calore JD, Snider GL, Franzblau C. Role of alpha-macroglobulin-elastase complexes in the pathogenesis of elastase-induced emphysema in hamsters. J Clin Invest. 1982 Apr; 69(4):920-31. PMID: 6176595.
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  97. Faris B, Mozzicato P, Ferrera R, Glembourtt M, Toselli P, Franzblau C. Collagen of brain microvessel preparations. Microvasc Res. 1982 Mar; 23(2):171-9. PMID: 7099014.
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  98. Franzblau C, Faris B. Biosynthesis of insoluble elastin in cell and organ cultures. Methods Enzymol. 1982; 82 Pt A:615-37. PMID: 7043211.
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  99. Stone PJ, Franzblau C, Kagan HM. Proteolysis of insoluble elastin. Methods Enzymol. 1982; 82 Pt A:588-605. PMID: 7043210.
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  100. Blondin J, Goldstein RH, Franzblau C. A gelatin-specific protease from hamster lung-derived cell cultures. In Vitro. 1982 Jan; 18(1):15-23. PMID: 6303944.
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  101. Bernhard WF, Colo NA, Szycher M, Wesolowski JS, Haudenschild CC, Franzblau CC, Parkman R, Liss RH. Development of a nonthrombogenic collagenous blood-prosthetic interface. Ann Surg. 1980 Sep; 192(3):369-81. PMID: 6448027.
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  102. Bernhard WF, Colo NA, Wesolowski JS, Szycher M, Fishbein MC, Parkman R, Franzblau CC, Haudenschild CC. Development of collagenous linings on impermeable prosthetic surfaces. J Thorac Cardiovasc Surg. 1980 Apr; 79(4):552-64. PMID: 6444687.
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  103. Franzblau, C., Faris, B. and Papaioannou, R., "Lysinonorleucine. A New Amino Acid from Hydrolsates of Elastin", Biochemistry 8:2833 (1969). Lysinonorleucine. A New Amino Acid from Hydrolsates of Elastin. Biochemistry. 1969; 8:2633.
  104. Franzblau, C. and Lent, R., In "Structure, Function and Evolution in Proteins", Brookhaven Symposia in Biology, 1968, Vol. 2, pp. 358-377 (1969). In "Structure, Function and Evolution in Proteins. Brookhaven Symposia in Biology. 1969; 2:358-377.
  105. Kang, A.H., Faris, B. and Franzblau, C., . ntramolecular Crosslink of Chick Skin Collagen. Biochem Biophys. Res. Comm. 1969; 36:345.
  106. Kim, I.C., Franzblau, C., Shirahama, T. and Cohen, A.S., "The Effect of Papain, Pronase, Nagarse, and Trypsin on Isolated Amyloid Fibrils", 181:465 (1969). The Effect of Papain, Pronase, Nagarse, and Trypsin on Isolated Amyloid Fibrils. Biochim. Biophys. Acta. 1969; 181:465.
  107. Lent, R.W., Smith, B.D., Salcedo, L.L., Faris, B. and Franzblau, C., "Studies on the Reduction of Elastin. II Evidence of the Presence of a-Aminoadipic Acid-d-Semialdehyde and Its Aldol Condensation Product", 8:2837 (1969). Studies on the Reduction of Elastin. II Evidence of the Presence of a-Aminoadipic Acid-d-Semialdehyde and Its Aldol Condensation Product. Biochemistry. 1969; 8:2837.
  108. Paz, M.A., Lent, R.W., Faris, B., Franzblau, C., Blumenfeld, O.O. and Gallop, P.M., . Aldehydes in Native and Denatured Calf Skin Tropocollagens. Biochem. Biophys. Res. Comm. 1969; 34:227.
  109. Salcedo, L.L., Faris, B. and Franzblau, C., . Studies on the Reduction of Elastin Biosynthesis and Stability of the Aldol Condensation Production of a-Aminoadipic Acid-d-Semialdehyde. Biochim, Biophys. Acta. 1969; 188:324.
  110. Aronson, R.B., Sinex, F.M., Franzblau, C. and Van Slyke, D.D., "", 242:809 (1967). Oxidation of The Protein-Bound Hydroxylysine by Periodate. J. Biol. Chem. 1967; 242:809.
  111. Kramsch, D., Franzblau, C. and Hollander, W., "", 36 (Suppl II):21 (1967). Alterations of Elastin in Human Atherosclerosis. Circulation. 1967; 36 (Supp i:21.
  112. Lent, R. and Franzblau, C., "", 26:43 (1967). Studies on Reduction of Bovine Elastin: Evidence for the Presence of D 6,7 Dehydrolysinonorleucine. Biochem. Biophys. Res. Comm. 1967; 26:43.
  113. ROSAN RC, CUNNINGHAM MA, FRANZBLAU CR. GROWTH OF TISSUE CULTURE ON CROSS-LINKED GELATIN. Exp Cell Res. 1965 May; 38:412-7. PMID: 14284519.
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  114. Franzblau, C., Sinex, F.M., Faris, B. and Lampidis, R. "Identification of a New Crosslinking Amino Acid in Elastin". Biochem. Biophys. Res. Comm. 1965; 21:575.
  115. Rosan, R.C., Cunningham, M.L. and Franzblau, C., "", Exp. Cell Res. 38:412 (1965). Growth of Tissue Culture on Crosslinked Gelatin. 1965.
  116. Carl Franzblau has been an author of approximately 220 original articles. Fifty are listed here.
  117. Franzblau, C., Chapter on Chemistry of Elastin Tissue in Dermatology and Modern Medicine, Fitzpatrick, Ed, McGraw-Hill (1970).
  118. Franzblau, C., "Elastin" in Comprehensive Biochemistry, Vol. 26c (1970).
  119. Franzblau, C., Faris, B., Lent, R.W., Salcedo, L.L., Smith, B.D., Jaffe, R. and Crombie, G., "Chemistry and Biosynthesis of the Crosslinks in Elastin" in Chemistry and Molecular Biology of Intercellular Matrix, E A Balazs, Ed., Vol. 1, p. 617 Academic Press, New York (1970).
  120. Franzblau, C., Kang, A.H. and Faris, B., "In Vitro Formation of Intermolecular Crosslinks in Chick Skin Collagen. II Kinetics", Biochem. Biophys. Res. Comm. 40:437 (1970).
  121. Franzblau, C., Kang, A.H. and Faris, B., "In Vitro Formation of Intermolecular Crosslinks in Chick Skin Collagen. II Kinetics", Biochem. Biophys. Res. Comm. 40:437 (1970).
  122. Kang, A.H., Faris, B. and Franzblau, C., "The In Vitro Formation of Intermolecular Crosslinks of Chick Skin Collagen", Biochem. Biophys. Res. Comm. 39:175 (1970).
  123. Kramsch. D., Hollander, W. and Franzblau, C., "Role of Arterial Elastin in Lipid Accumulation in Human Atherosclerosis", Int'l Symposium on Atherosclerosis, Chicago (1970).
  124. Crombie, G., Faris, B., Gallop, P.M. and Franzblau, C., "Hydrogenation of the Reduced AldolCondensation Product from Elastin", Biochemistry 10:4145 (1971).
  125. Hollander, W., Kramsch, D. and Franzblau, C., "Vascular Bound Immunoglobulin in the HumanArteriosclerotic Plaque", Circulation 44:2-17A (1971).
  126. Kramsch, D., Franzblau, C. and Hollander, W., "The Protein and Lipid Composition of Arterial Elastin and its Relationship to Lipid Accumulation in the Arteriosclerotic Plaque", J. Clin. Invest. 50:1666 (1971).
  127. Oppenheim, F., Hay, D. and Franzblau, C., "Proline-Rich Protein from Human Parotid Saliva. I. Isolation and Partial Characterization", Biochemistry 10:4233 (1971).
  128. Siegel, R., Kagan, H.M., Franzblau, C. and Martin, G., "In Vitro Maturation of Bone Collagen", Israel J. Med. Sci. 7:3 (1971).
  129. Kagan, H.M., Crombie, G., Jordan, R. and Franzblau, C., "Proteolysis of Elastin-Ligand Complexes. Stimulation of Elastase Digestion of Insoluble Elastin by Sodium Dodecyl Sulfate", Biochemistry 11:3412 (1972).
  130. Baum, B.J., Franzblau, C. and Kagan, H.M., "Isolation and Partial Characterization of Collagen from Newt Tail", Comparative Biochemistry 47B:805 (1973).
  131. Baum, B.J., Troxler, R.F., Kagan, H.M., Grasso, J.A., Faris, B. and Franzblau, C., "Incorporation of L- Azetidine-2-Carboxylic Acid into Hemoglobin in Rabbit Reticulocytes", Biochem. Biophys. Res. Comm. 43:1350 (1973).
  132. Cohen, A.J., Slovin, D.L., Franzblau, C. and Sinex, F.M., "A Self-Paced Biochemistry Course for Medical Students", J. Med. Ed. 48:289 (1973).
  133. Crombie, G., Foster, J.A. and Franzblau, C., "Isolation of the Tetrapeptide Gly-Val-Pro-Gly from an Elastin Digest", Biochem. Biophys. Res. Comm. 52:1228 (1973).
  134. Foster, J.A., Bruenger, E., Hu, C.L., Albertson, K. and Franzblau, C., "A New Improved Technique for Automated Sequencing of Non-Polar Peptides", Biochem. Biophys. Res. Comm. 53:70 (1973).
  135. Foster, J.A., Gray, W.R. and Franzblau, C., "Isolation and Characterization of Crosslinked Peptides from Elastin", Biochim. Biophys. Acta 313:363 (1973).
  136. Kagan, H.M., Hewitt, N. and Franzblau, C., "A Microenvironmental Probe of Elastin, Properties of Solubilized Congo Red-Elastin Complex", Biochim. Biophys. Acta 322:258 (1973).
  137. Lian, J.B., Morris, S., Faris, B., Albright J. and Franzblau, C., "The Effects of Acetic Acid and Pepsin on the Crosslinkages and Ultrastructure of Corneal Collagen", Biochim. Biophys. Acta 328:193 (1973).
  138. Tanzer, M.L., Housley, T., Berube, L., Fairweather, R., Franzblau, C. and Gallop, P.M., "Structure of Two Histidine-Containing Crosslinks from Collagen", J. Biol. Chem. 247:393 (1973).
  139. Foster, J.A., Rubin, L., Kagan, H.M. and Franzblau, C., "Isolation and Characterization of Crosslinked Peptides from Elastin", J. Biol. Chem. 249:6191 (1974).
  140. Hollander, W., Kramsch, D.M., Franzblau, C., Paddock, J. and Colombo, M.A., "Suppression of Atheromatous Fibrous Plaque Formation by Antiproliferative and Anti-inflammatory Drugs", Circulation Research Vols. 34 and 35 (1974).
  141. Jordan, R., Hewitt, N., Lewis, W., Kagan, H. and Franzblau, C., "Regulation of Elastase-Catalyzed Hydrolysis of Insoluble Elastin by Synthetic and Naturally Occurring Hydrophobic Ligands", Biochemistry 13:3497 (1974).
  142. Kagan H.M., Hewitt, N. A., Salcedo, L.L. and Franzblau, C., "Catalytic Activity of Aortic Lysyl Oxidase in an Insoluble Enzyme-Substrate Complex", Biochim. Biophys. Acta 365:223 (1974).
  143. Kramsch, D.M., Franzblau, C. and Hollander, W., "Components of the Protein-Lipid Complex of Arterial Elastin. Their Role in the Retention of Lipid in Atherosclerotic Lesions", Adv. Exp. Med. Biol. 43:193 (1974).
  144. Mukherjee, D.P., Hoffman, A.S. and Franzblau, C., "The Physical Properties and Molecular Structure of Ligamentum Nuchae Elastin", Biopolymers 13:2447 (1974).
  145. Rowe, D.W., McGoodwin, E.B., Martin, G.R., Sussman, M.D., Grahn, D., Faris B. and Franzblau, C., "A Sex-Linked Defect in the Crosslinking of Collagen and Elastin Associated with the Mottled Locus in Mice", J. Exp. Med. 139:180 (1974).
  146. Snider, G.L., Hayes, J.A., Franzblau, C., Kagan, H.M., Stone, P., Korthy, A.L., "Elastolytic and Emphysema Inducing Properties of Papain", Amer. Rev. Resp. Dis. 110:254 (1974).
  147. Snider, G.L., Hayes, J.A., Korthy, A.L., Franzblau, C. and Stone, P.J., "Evidence of Destruction of Lung Tissue in Elastase Induced Emphysema in Hamsters", Chest 66:336 (1974).
  148. Yablon, I.G., Franzblau, C. and Leach, R., "The Response of Transplanted Articular Cartilage to Growth Hormone", J. Bone and Joint Surg. 56A:322 (1974).
  149. Baum, B.J., Faris, B. and Franzblau, C., "Further Studies on Newt Tail Collagen: Description of Lysine Derived Crosslinks", Comparative Biochemistry 51B:51(1975).
  150. Baum, B., Johnson, L., Franzblau, C. and Troxler, R., "Incorporation of L-Azetidine-2-Carboxylic Acid into Hemoglobulin in Rabbit Reticulocytes In Vitro", J. Biol. Chem. 250:1464 (1975).
  151. Brown, A., Foster, J.A. Voynow, P., Franzblau, C. and Troxler, R., "AIIophycocyanin from the Filamentous Cyanophyte, Phormidium Luridum", Biochemistry 14:3581(1975).
  152. Diferranti, N., Leachman, R.D., Angelini, P., Donnelly, P.V., Francis, G., Almazan, A., Segni, G., Franzblau, C. and Jordan, R.E., "Ehlers-Danlos Type V (X-Linked Form).: A Lysyl oxidase Deficiency", Disorders of Connective Tissue Vol. XI (1975).
  153. Foster, J.A., Shapiro, R., Voynow, P., Crombie, G. Faris, B. and Franzblau, C., "Isolation of Soluble Elastin from Lathyritic Chicks. Comparison to Tropoelastin for Copper Deficient Pigs", Biochemistry 14 4343 (1975).
  154. Grant, M.M., Brown, A.S., Crowin, L.M., Troxler, R.F. and Franzblau, C., "Effect of L-Azetidine 2- Carboxylic Acid on Growth and Proline Metabolism in Escherichia Coli", Biochim. Biophys. Acta 404:180 (1975).
  155. Juricova, M., Franzblau, C., Faris, B., Deyl, Z. and Adam, M., "Some Lysine-Containing Peptides from the Elastase Digest of Elastin and their Relation to Lysinonorleucine Crosslink", Biochim. Biophys. Acta 386:239 (1975).
  156. Troxler, R.F., Foster, J.A., Brown, A.S. and Franzblau, C., "The a and ß Subunits of Cyanidium?????????????Caldarium Phycocyanin: Properties and Amino Acid Sequences at the Amino Terminus", Biochemistry 14:268 (1975).
  157. Brody, J.S., Kagan, H.M., Manalo, A.D., Hu, C.L. and Franzblau, C., "Lung Lysyl Oxidase and Elastin Synthesis During Compensatory Lung Growth", Chest 69:271 (1976).
  158. Faris, B., Salcedo, L., Cook, V., Johnson, L., Foster, J.A. and Franzblau, C., "Synthesis of Connective Tissue Protein in Rabbit Smooth Muscle Cells", Biochim. Biophys. Acta 418:93 (1976).
  159. Faris, B., Salcedo, L., Cook, V., Johnson, L., Foster, J.A. and Franzblau, C., "Synthesis of Connective Tissue Protein in Rabbit Smooth Muscle Cells", Biochim. Biophys. Acta 418:93 (1976).
  160. Foster, J.A., Bruenger, E., Rubin, L., Imberman, M., Kagan, H.M., Mecham, R. and Franzblau, C., "Circular Dichroism Studies of an Elastin Crosslinked Peptide", Biopolymers 15:833 (1976).
  161. Foster, J.A., Knaack, D., Faris, B., Moscaritolo, R., Salcedo, L., Skinner, M. and Franzblau, C., "Development of a Specific Immunological Assay for Tropoelastin and its Application to Tissue Culture Studies", Biochim. Biophys. Acta 446:51-55 (1976).
  162. Foster, J.A., Mecham, R. and Franzblau, C., "Isolation of a High Molecular Weight Species of Soluble Elastin", Biochem. Biophys. Res. Comm. 72:1399 (1976).
  163. Franzblau, C., Schmid, K., Faris, B., Beldekas, J., Garvin, P., Kagan, H.M. and Baum, B.J., "The Interaction of Collagen with a1-Acid Glycoprotein", Biochim. Biophys. Acta 427:302 (1976).
  164. Mecham, R., Foster, J.A. and Franzblau, C., "Intrinsic Enzyme Activity Associated with Tropoelastin", Biochim. Biophys. Acta 446:245 (1976).
  165. Mukherjee, D.P., Kagan, H.M., Jordan, R.E. and Franzblau, C., "Effect of Hydrophobic Elastin Ligands on the Stress-Strain Properties of Elastin Fibers", Conn. Tiss. Res. 4:177 (1976).
  166. Trasko, C.S., Franzblau, C. and Troxler, R.F., "Incorporation of L-Azetidine-2-Carboxylic Acid into Hemoglobin S in Sickle Erythrocytes In Vitro", Biochim. Biophys. Acta 447:425-435 (1976).
  167. Foster, J.A. and Franzblau, C., "Environmental Effects on Lung Elastin Tissue", BEEP Symposium, Ann Arbor, Michigan, Science (1977).
  168. Foster, J.A., Imberman, M. Mecham, R., Faris, B. and Franzblau, C., "Proelastin", International Meeting on Elastin, Experimental Medicine, Vol. 79:351 (1977).
  169. Franzblau, C., Foster, J.A. and Faris, B., "Role of Crosslinking in Fiber Formation", International Meeting on Elastin, Experimental Medicine Vol. 79, 315 (1977).
  170. Franzblau, C. Hayes, J.A. and Snider, G.L., "Biochemical Insights into the Development of Connective Tissue", In: The Development of the Lung, Hodson, WA. (Ed.), In: Monograph #1 of the Series, "Lung Biology in Health and Disease", Lenfant, C., (Ed.), Marcel Dekker Inc., New York (1977).
  171. Kagan, H.M., Jordan, R.E., Lerch, R.M., Mukherjee, D.P., Stone, P. and Franzblau, C., "Factors Affecting the Proteolytic Degradation of Elastin", International Meeting on Elastin, Experimental Medicine, Vol. 79:189 (1977).
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