Keywords
Last Name

Carl Franzblau, PhD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentBiochemistry
Address72 E. Concord St
Boston MA 02118
Phone(617) 638-5320
ORCID ORCID Icon0000-0001-9248-6324
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine
DepartmentGraduate Medical Sciences, Division of

 Awards and Honors

Start-EndDescription
1986Boston University: Metcaf Cup and Prize
2009A Einstein College of Medicine: Distinguished PhD Alumnus Award
1988Roger Williams Univ: Honary Doctor of Science
1966-1970American Heart Association: Established Investigator
1988Czech National Acad: G Mendel award
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Janardhan V, Wolf PA, Kase CS, Massaro JM, D'Agostino RB, Franzblau C, Wilson PW. Anticardiolipin antibodies and risk of ischemic stroke and transient ischemic attack: the Framingham cohort and offspring study. Stroke. 2004 Mar; 35(3):736-41.
    View in: PubMed
  2. Hsiao H, Stone PJ, Toselli P, Rosenbloom J, Franzblau C, Schreiber BM. The role of the carboxy terminus of tropoelastin in its assembly into the elastic fiber. Connect Tissue Res. 1999; 40(2):83-95.
    View in: PubMed
  3. Stone PJ, Lucey EC, Snider GL, Franzblau C. Distribution of elastin in hamsters and the turnover rates of different elastin pools. Proc Soc Exp Biol Med. 1997 May; 215(1):94-101.
    View in: PubMed
  4. Bhatia S, Bergethon PR, Blease S, Kemper T, Rosiello A, Zimbardi GP, Franzblau C, Spatz EL. A synthetic dural prosthesis constructed from hydroxyethylmethacrylate hydrogels. J Neurosurg. 1995 Nov; 83(5):897-902.
    View in: PubMed
  5. Stone PJ, Franzblau C. Increase in urinary desmosine and pyridinoline during postpartum involution of the uterus in humans. Proc Soc Exp Biol Med. 1995 Oct; 210(1):39-42.
    View in: PubMed
  6. Stone PJ, Konstan MW, Berger M, Dorkin HL, Franzblau C, Snider GL. Elastin and collagen degradation products in urine of patients with cystic fibrosis. Am J Respir Crit Care Med. 1995 Jul; 152(1):157-62.
    View in: PubMed
  7. Stone PJ, Korn JH, North H, Lally EV, Miller LC, Tucker LB, Strongwater S, Snider GL, Franzblau C. Cross-linked elastin and collagen degradation products in the urine of patients with scleroderma. Arthritis Rheum. 1995 Apr; 38(4):517-24.
    View in: PubMed
  8. Stone PJ, Gottlieb DJ, O'Connor GT, Ciccolella DE, Breuer R, Bryan-Rhadfi J, Shaw HA, Franzblau C, Snider GL. Elastin and collagen degradation products in urine of smokers with and without chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1995 Apr; 151(4):952-9.
    View in: PubMed
  9. Stone PJ, Morris TA, Franzblau C, Snider GL. Preliminary evidence that augmentation therapy diminishes degradation of cross-linked elastin in alpha-1-antitrypsin-deficient humans. Respiration. 1995; 62(2):76-9.
    View in: PubMed
  10. Schreiber BM, Jones HV, Franzblau C. Apolipoprotein E expression in aortic smooth muscle cells: the effect of beta VLDL. J Lipid Res. 1994 Jul; 35(7):1177-86.
    View in: PubMed
  11. Trinkaus-Randall V, Banwatt R, Wu XY, Leibowitz HM, Franzblau C. Effect of pretreating porous webs on stromal fibroplasia in vivo. J Biomed Mater Res. 1994 Feb; 28(2):195-202.
    View in: PubMed
  12. Stone PJ, Lucey EC, Snider GL, Franzblau C. Effect of diet on urinary excretion of desmosine and hydroxylysyl pyridinoline. Am J Respir Crit Care Med. 1994 Jan; 149(1):174-7.
    View in: PubMed
  13. Stone PJ, Lucey EC, Breuer R, Christensen TG, Zaslow MC, Clark RA, Franzblau C, Snider GL. Oxidants from neutrophil myeloperoxidase do not enhance elastase-induced emphysema in the hamster. Respiration. 1993; 60(3):137-43.
    View in: PubMed
  14. Hospelhorn AC, Martin BM, Franzblau C. Type IV collagen synthesis and accumulation in neonatal rat aortic smooth muscle cell cultures. Matrix. 1992 Nov; 12(5):352-61.
    View in: PubMed
  15. Stone PJ, Bryan-Rhadfi J, Shaw HA, Franzblau C. Isolation of hydroxylysyl pyridinoline, a mature collagen crosslink from neonatal rat aorta smooth muscle cell cultures. Matrix. 1992 Nov; 12(5):381-7.
    View in: PubMed
  16. Schreiber BM, Jones HV, Toselli P, Franzblau C. Long-term treatment of neonatal aortic smooth muscle cells with beta VLDL induces cholesterol accumulation. Atherosclerosis. 1992 Aug; 95(2-3):201-10.
    View in: PubMed
  17. Toselli P, Faris B, Sassoon D, Jackson BA, Franzblau C. In-situ hybridization of tropoelastin mRNA during the development of the multilayered neonatal rat aortic smooth muscle cell culture. Matrix. 1992 Aug; 12(4):321-32.
    View in: PubMed
  18. Faris B, Tan OT, Toselli P, Franzblau C. Long-term neonatal rat aortic smooth muscle cell cultures: a model for the tunica media of a blood vessel. Matrix. 1992 Jun; 12(3):185-8.
    View in: PubMed
  19. Wolfe BL, Schreiber BM, Bryan-Rhadfi J, Stone PJ, Franzblau C. Alterations of tropoelastin biosynthesis by elastase damage to smooth muscle cell matrices. Matrix. 1992 Apr; 12(2):163-71.
    View in: PubMed
  20. Martin BM, Ritchie AR, Toselli P, Franzblau C. Elastin synthesis and accumulation in irradiated smooth muscle cell cultures. Connect Tissue Res. 1992; 28(3):181-9.
    View in: PubMed
  21. Trinkaus-Randall V, Banwatt R, Capecchi J, Leibowitz HM, Franzblau C. In vivo fibroplasia of a porous polymer in the cornea. Invest Ophthalmol Vis Sci. 1991 Dec; 32(13):3245-51.
    View in: PubMed
  22. Faris B, Jackson LE, Schreiber BM, Martin BM, Jones HV, Franzblau C. A controlled precursor add-back model of elastogenesis in smooth muscle cell cultures. Matrix. 1991 Nov; 11(5):367-72.
    View in: PubMed
  23. Jackson LE, Faris B, Martin BM, Jones HV, Rich CB, Foster JA, Franzblau C. The effect of beta-aminopropionitrile on elastin gene expression in smooth muscle cell cultures. Biochem Biophys Res Commun. 1991 Sep 16; 179(2):939-44.
    View in: PubMed
  24. Stone PJ, Bryan-Rhadfi J, Lucey EC, Ciccolella DE, Crombie G, Faris B, Snider GL, Franzblau C. Measurement of urinary desmosine by isotope dilution and high performance liquid chromatography. Correlation between elastase-induced air-space enlargement in the hamster and elevation of urinary desmosine. Am Rev Respir Dis. 1991 Aug; 144(2):284-90.
    View in: PubMed
  25. Tan OT, Faris B, Franzblau C. Aortic elastin fluorescence afterin vivo labeling with Congo red. J Fluoresc. 1991 Jun; 1(2):147-51.
    View in: PubMed
  26. Berk JL, Franzblau C, Goldstein RH. Recombinant interleukin-1 beta inhibits elastin formation by a neonatal rat lung fibroblast subtype. J Biol Chem. 1991 Feb 15; 266(5):3192-7.
    View in: PubMed
  27. Stone PJ, Lucey EC, Bryan-Rhadfi J, Snider GL, Franzblau C. Isolation of urinary desmosine by HPLC, amino acid analysis, and quantification by isotope dilution. Ann N Y Acad Sci. 1991; 624:355-7.
    View in: PubMed
  28. Kaufmann J, Jorgensen RW, Martin BM, Franzblau C. Monocyte activation by smooth muscle cell-derived matrices. Atherosclerosis. 1990 Dec; 85(2-3):113-25.
    View in: PubMed
  29. Trinkaus-Randall V, Capecchi J, Sammon L, Gibbons D, Leibowitz HM, Franzblau C. In vitro evaluation of fibroplasia in a porous polymer. Invest Ophthalmol Vis Sci. 1990 Jul; 31(7):1321-6.
    View in: PubMed
  30. Trinkaus-Randall V, Newton AW, Franzblau C. The synthesis and role of integrin in corneal epithelial cells in culture. Invest Ophthalmol Vis Sci. 1990 Mar 1; 31(3):440-7.
    View in: PubMed
  31. Sipe JD, Gonnerman WA, Loose LD, Knapschaefer G, Xie WJ, Franzblau C. Direct binding enzyme-linked immunosorbent assay (ELISA) for serum amyloid A (SAA). J Immunol Methods. 1989 Dec 20; 125(1-2):125-35.
    View in: PubMed
  32. Franzblau C, Pratt CA, Faris B, Colannino NM, Offner GD, Mogayzel PJ, Troxler RF. Role of tropoelastin fragmentation in elastogenesis in rat smooth muscle cells. J Biol Chem. 1989 Sep 5; 264(25):15115-9.
    View in: PubMed
  33. Bergethon PR, Mogayzel PJ, Franzblau C. Effect of the reducing environment on the accumulation of elastin and collagen in cultured smooth-muscle cells. Biochem J. 1989 Feb 15; 258(1):279-84.
    View in: PubMed
  34. Bergethon PR, Trinkaus-Randall V, Franzblau C. Modified hydroxyethylmethacrylate hydrogels as a modelling tool for the study of cell-substratum interactions. J Cell Sci. 1989 Jan; 92 ( Pt 1):111-21.
    View in: PubMed
  35. Trinkaus-Randall V, Newton A, Franzblau C. Influence of substratum on corneal epithelial cell growth and protein synthesis. Invest Ophthalmol Vis Sci. 1988 Dec; 29(12):1800-9.
    View in: PubMed
  36. Stone PJ, Morris SM, Martin BM, McMahon MP, Faris B, Franzblau C. Repair of protease-damaged elastin in neonatal rat aortic smooth muscle cell cultures. J Clin Invest. 1988 Nov; 82(5):1644-54.
    View in: PubMed
  37. Hospelhorn AC, Faris B, Mogayzel PJ, Tan OT, Franzblau C. Congo red binding of elastin in aortic smooth muscle cell cultures. J Histochem Cytochem. 1988 Oct; 36(10):1353-8.
    View in: PubMed
  38. Barone LM, Wolfe BL, Faris B, Franzblau C. Elastin mRNA levels and insoluble elastin accumulation in neonatal rat smooth muscle cell cultures. Biochemistry. 1988 May 3; 27(9):3175-82.
    View in: PubMed
  39. Snider GL, Lucey EC, Faris B, Jung-Legg Y, Stone PJ, Franzblau C. Cadmium-chloride-induced air-space enlargement with interstitial pulmonary fibrosis is not associated with destruction of lung elastin. Implications for the pathogenesis of human emphysema. Am Rev Respir Dis. 1988 Apr; 137(4):918-23.
    View in: PubMed
  40. Trinkaus-Randall V, Capecchi J, Newton A, Vadasz A, Leibowitz H, Franzblau C. Development of a biopolymeric keratoprosthetic material. Evaluation in vitro and in vivo. Invest Ophthalmol Vis Sci. 1988 Mar; 29(3):393-400.
    View in: PubMed
  41. Trinkaus-Randall V, Newton AW, Gipson IK, Franzblau C. Carbohydrate moieties of the basal lamina: their role in attachment and spreading of basal corneal epithelial cells. Cell Tissue Res. 1988 Feb; 251(2):315-23.
    View in: PubMed
  42. Weintraub LR, Goral A, Grasso J, Franzblau C, Sullivan A, Sullivan S. Collagen biosynthesis in iron overload. Ann N Y Acad Sci. 1988; 526:179-84.
    View in: PubMed
  43. Stone PJ, Lucey EC, Calore JD, McMahon MP, Snider GL, Franzblau C. Defenses of the hamster lung against human neutrophil and porcine pancreatic elastase. Respiration. 1988; 54(1):1-15.
    View in: PubMed
  44. Ohishi H, Hess D, Kosakai M, Schmid K, Hausmann J, Mogayzel PJ, Faris B, Franzblau C. Glycosaminoglycan content in neonatal rat aortic smooth muscle cell cultures. Atherosclerosis. 1988 Jan; 69(1):61-8.
    View in: PubMed
  45. Schreiber BM, Martin BM, Hollander W, Franzblau C. beta-VLDL-induced alterations in growth potentiating activity produced by mononuclear phagocytes. Atherosclerosis. 1988 Jan; 69(1):69-79.
    View in: PubMed
  46. Stone PJ, McMahon MP, Morris SM, Calore JD, Franzblau C. Elastin in a neonatal rat smooth muscle cell culture has greatly decreased susceptibility to proteolysis by human neutrophil elastase. An in vitro model of elastolytic injury. In Vitro Cell Dev Biol. 1987 Oct; 23(10):663-76.
    View in: PubMed
  47. Bernhard WF, Colo NA, Wesolowski JS, Szycher M, Fishbein MC, Parkman R, Franzblau CC, Haudenschild CC. Development of collagenous linings on impermeable prosthetic surfaces. J Thorac Cardiovasc Surg. 1980 Apr; 79(4):552-64.
    View in: PubMed
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