Keywords
Last Name

Xueping Fan, MD, PhD

TitleInstructor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionNephrology
Address650 Albany St Evans Biomed Research Ctr
Boston MA 02118
Phone(617) 638-7333
ORCID ORCID Icon0000-0002-3715-6864
Other Positions
InstitutionBoston Medical Center

 Research Expertise & Professional Interests
Expertise includes: Protein biochemistry; Signaling pathway study; Cell biology; Molecular genetics; Molecular nephrology; Neuroscience; and Pharmacology.

 Self-Described Keywords
  • cytoskeleton
  • glomerular filtration barrier
  • nephrin
  • netrin
  • podocytes
  • protein interaction
  • Robo
  • Signaling pathway
  • slit
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W. SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. JCI Insight. 2016 Nov 17; 1(19):e86934. PMID: 27882344.
    View in: PubMed
  2. Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W. Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26; 2(1):52-61. PMID: 22840396.
    View in: PubMed
  3. Lu W, van Eerde AM, Fan X, Quintero-Rivera F, Kulkarni S, Ferguson H, Kim HG, Fan Y, Xi Q, Li QG, Sanlaville D, Andrews W, Sundaresan V, Bi W, Yan J, Giltay JC, Wijmenga C, de Jong TP, Feather SA, Woolf AS, Rao Y, Lupski JR, Eccles MR, Quade BJ, Gusella JF, Morton CC, Maas RL. Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux. Am J Hum Genet. 2007 Apr; 80(4):616-32. PMID: 17357069.
    View in: PubMed
  4. Abu-Baker A, Laganiere S, Fan X, Laganiere J, Brais B, Rouleau GA. Cytoplasmic targeting of mutant poly(A)-binding protein nuclear 1 suppresses protein aggregation and toxicity in oculopharyngeal muscular dystrophy. Traffic. 2005 Sep; 6(9):766-79. PMID: 16101680.
    View in: PubMed
  5. Fan X, Labrador JP, Hing H, Bashaw GJ. Slit stimulation recruits Dock and Pak to the roundabout receptor and increases Rac activity to regulate axon repulsion at the CNS midline. Neuron. 2003 Sep 25; 40(1):113-27. PMID: 14527437.
    View in: PubMed
  6. Fan X, Messaed C, Dion P, Laganiere J, Brais B, Karpati G, Rouleau GA. HnRNP A1 and A/B interaction with PABPN1 in oculopharyngeal muscular dystrophy. Can J Neurol Sci. 2003 Aug; 30(3):244-51. PMID: 12945950.
    View in: PubMed
  7. Fan X, Rouleau GA. Progress in understanding the pathogenesis of oculopharyngeal muscular dystrophy. Can J Neurol Sci. 2003 Feb; 30(1):8-14. PMID: 12619777.
    View in: PubMed
  8. Fan X, Dion P, Laganiere J, Brais B, Rouleau GA. Oligomerization of polyalanine expanded PABPN1 facilitates nuclear protein aggregation that is associated with cell death. Hum Mol Genet. 2001 Oct 1; 10(21):2341-51. PMID: 11689481.
    View in: PubMed
  9. Jannatipour M, Dion P, Khan S, Jindal H, Fan X, Laganière J, Chishti AH, Rouleau GA. Schwannomin isoform-1 interacts with syntenin via PDZ domains. J Biol Chem. 2001 Aug 31; 276(35):33093-100. PMID: 11432873.
    View in: PubMed
  10. Fan X, Robaire B. Orchidectomy induces a wave of apoptotic cell death in the epididymis. Endocrinology. 1998 Apr; 139(4):2128-36. PMID: 9529002.
    View in: PubMed
  11. Robaire B, Fan X. Regulation of apoptotic cell death in the rat epididymis. J Reprod Fertil Suppl. 1998; 53:211-4. PMID: 10645279.
    View in: PubMed
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