Keywords
Last Name

Selwyn A. Broitman, PhD

TitleEmeritus Professor
InstitutionBoston University School of Medicine
DepartmentMicrobiology
Address72 E. Concord St Instructional (L)
Boston MA 02118
Phone(617) 638-5342
Other Positions
TitleEmeritus Professor
InstitutionBoston University School of Medicine
DepartmentPathology & Laboratory Medicine

TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

 Self-Described Keywords
  • administrative expertise includes the medical and graduate school admissions and counseling. .
  • cancers of the gastrointestinal tract
  • gastrointestinal absorption
  • gut microflora
  • microbial and parasitic infections of the GI tract
  • mycologic infections
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Gaposchkin DP, Zoeller RA, Broitman SA. Incorporation of polyunsaturated fatty acids into CT-26, a transplantable murine colonic adenocarcinoma. Lipids. 2000 Feb; 35(2):181-6. PMID: 10757549.
    View in: PubMed
  2. Panda SK, Broitman SA. Fecal excretion pattern of bile acids in rats fed high fat diets and neomycin in induced colon tumorigenesis. Bioorg Med Chem Lett. 1999 Sep 6; 9(17):2459-62. PMID: 10498188.
    View in: PubMed
  3. Panda SK, Chattoraj SC, Broitman SA. Correlation of neomycin, faecal neutral and acid sterols with colon carcinogenesis in rats. Br J Cancer. 1999 Jun; 80(8):1132-6. PMID: 10376962.
    View in: PubMed
  4. Cerda SR, Wilkinson J, Branch SK, Broitman SA. Enhancement of sterol synthesis by the monoterpene perillyl alcohol is unaffected by competitive 3-hydroxy-3-methylglutaryl-CoA reductase inhibition. Lipids. 1999 Jun; 34(6):605-15. PMID: 10405975.
    View in: PubMed
  5. Cerda SR, Wilkinson J, Thorgeirsdottir S, Broitman SA. R-(+)-perillyl alcohol-induced cell cycle changes, altered actin cytoskeleton, and decreased ras and p34(cdc2) expression in colonic adenocarcinoma SW480 cells. J Nutr Biochem. 1999 Jan; 10(1):19-30. PMID: 15539246.
    View in: PubMed
  6. Newberne PM, Broitman S, Schrager TF. Esophageal carcinogenesis in the rat: zinc deficiency, DNA methylation and alkyltransferase activity. Pathobiology. 1997; 65(5):253-63. PMID: 9459495.
    View in: PubMed
  7. Newberne PM, Schrager TF, Broitman S. Esophageal carcinogenesis in the rat: zinc deficiency and alcohol effects on tumor induction. Pathobiology. 1997; 65(1):39-45. PMID: 9200188.
    View in: PubMed
  8. Broitman SA, Wilkinson J, Cerda S, Branch SK. Effects of monoterpenes and mevinolin on murine colon tumor CT-26 in vitro and its hepatic "metastases" in vivo. Adv Exp Med Biol. 1996; 401:111-30. PMID: 8886130.
    View in: PubMed
  9. Cerda SR, Wilkinson J, Broitman SA. Regulation of cholesterol synthesis in four colonic adenocarcinoma cell lines. Lipids. 1995 Dec; 30(12):1083-92. PMID: 8614298.
    View in: PubMed
  10. Treon SP, Anand B, Ulevitch R, Broitman SA. CD14 mediated endogenous TNF-alpha release in HL60 AML cells: a potential model for CD14 mediated endogenous cytokine release in the treatment of AML. Leuk Res. 1994 Jan; 18(1):17-21. PMID: 7507190.
    View in: PubMed
  11. Treon SP, Thomas P, Broitman SA. Lipopolysaccharide (LPS) processing by Kupffer cells releases a modified LPS with increased hepatocyte binding and decreased tumor necrosis factor-alpha stimulatory capacity. Proc Soc Exp Biol Med. 1993 Feb; 202(2):153-8. PMID: 8424104.
    View in: PubMed
  12. Broitman SA, Cerda S, Wilkinson J. Cholesterol metabolism and colon cancer. Prog Food Nutr Sci. 1993 Jan-Mar; 17(1):1-40. PMID: 8502754.
    View in: PubMed
  13. Treon SP, Broitman SA. Monoclonal antibody therapy in the treatment of Reye's syndrome. Med Hypotheses. 1992 Nov; 39(3):238-42. PMID: 1474950.
    View in: PubMed
  14. Treon SP, Broitman SA. Beneficial effects of post-transfusional hepatitis in acute myelogenous leukemia may be mediated by lipopolysaccharides, tumor necrosis factor alpha and interferon gamma. Leukemia. 1992 Oct; 6(10):1036-42. PMID: 1405756.
    View in: PubMed
  15. Broitman SA, Cannizzo F. A model system for studying nutritional interventions on colon tumor growth: effects of marine oil. Adv Exp Med Biol. 1992; 322:103-18. PMID: 1442289.
    View in: PubMed
  16. Treon SP, Anand B, Chou IN, Broitman SA. Growth restraint and differentiation by LPS/TNF-alpha/IFN-gamma reorganization of the microtubule network in human leukemia cell lines. Leukemia. 1992; 6 Suppl 3:141S-145S. PMID: 1602811.
    View in: PubMed
  17. Fox ES, Broitman SA, Thomas P. Bacterial endotoxins and the liver. Lab Invest. 1990 Dec; 63(6):733-41. PMID: 2255181.
    View in: PubMed
  18. Fox ES, Thomas P, Broitman SA. Hepatic mechanisms for clearance and detoxification of bacterial endotoxins. J Nutr Biochem. 1990 Dec; 1(12):620-8. PMID: 15539181.
    View in: PubMed
  19. Fabricant M, Broitman SA. Evidence for deficiency of low density lipoprotein receptor on human colonic carcinoma cell lines. Cancer Res. 1990 Feb 1; 50(3):632-6. PMID: 2297703.
    View in: PubMed
  20. Cannizzo F, Broitman SA. Postpromotional effects of dietary marine or safflower oils on large bowel or pulmonary implants of CT-26 in mice. Cancer Res. 1989 Aug 1; 49(15):4289-94. PMID: 2743315.
    View in: PubMed
  21. Hatchigian EA, Santos JI, Broitman SA, Vitale JJ. Vitamin A supplementation improves macrophage function and bacterial clearance during experimental salmonella infection. Proc Soc Exp Biol Med. 1989 May; 191(1):47-54. PMID: 2654947.
    View in: PubMed
  22. Fox ES, Thomas P, Broitman SA. Clearance of gut-derived endotoxins by the liver. Release and modification of 3H, 14C-lipopolysaccharide by isolated rat Kupffer cells. Gastroenterology. 1989 Feb; 96(2 Pt 1):456-61. PMID: 2642878.
    View in: PubMed
  23. Fox ES, Thomas P, Broitman SA. Uptake and modification of 125I-lipopolysaccharide by isolated rat Kupffer cells. Hepatology. 1988 Nov-Dec; 8(6):1550-4. PMID: 3192168.
    View in: PubMed
  24. Fox ES, Thomas P, Broitman SA. Comparative studies of endotoxin uptake by isolated rat Kupffer and peritoneal cells. Infect Immun. 1987 Dec; 55(12):2962-6. PMID: 2824379.
    View in: PubMed
  25. Bigatello LM, Broitman SA, Fattori L, Di Paoli M, Pontello M, Bevilacqua G, Nespoli A. Endotoxemia, encephalopathy, and mortality in cirrhotic patients. Am J Gastroenterol. 1987 Jan; 82(1):11-5. PMID: 3799574.
    View in: PubMed
  26. Kraus LJ, Williams RM, Murphy K, Broitman SA. T-cell mitogenesis and natural killer cell activity in colonic tumor-bearing and nontumor-bearing rats fed diets high in lipid with and without cholesterol. Nutr Cancer. 1987; 9(2-3):159-70. PMID: 3494235.
    View in: PubMed
  27. du Moulin GC, Lynch SE, Hedley-Whyte J, Broitman SA. The detection of gram-negative bacteria in the blood of septic rats by a Limulus amebocyte lysate assay. Prog Clin Biol Res. 1987; 231:349-56. PMID: 3588630.
    View in: PubMed
  28. Broitman SA. Clostridium difficile antibiotic-associated colitis. Am J Gastroenterol. 1986 Oct; 81(10):1005-6. PMID: 3766494.
    View in: PubMed
  29. Broitman SA. Dietary cholesterol, serum cholesterol, and colon cancer: a review. Adv Exp Med Biol. 1986; 206:137-52. PMID: 3296679.
    View in: PubMed
  30. Broitman SA. Cholesterol conundrums: the relationship between dietary and serum cholesterol in colon cancer. Prog Clin Biol Res. 1986; 222:435-59. PMID: 3097656.
    View in: PubMed
  31. du Moulin GC, Paterson D, Hedley-Whyte J, Broitman SA. E. coli peritonitis and bacteremia cause increased blood-brain barrier permeability. Brain Res. 1985 Aug 12; 340(2):261-8. PMID: 2411352.
    View in: PubMed
  32. du Moulin GC, Lynch SE, Hedley-Whyte J, Broitman SA. Detection of gram-negative bacteremia by limulus amebocyte lysate assay: evaluation in a rat model of peritonitis. J Infect Dis. 1985 Jan; 151(1):148-52. PMID: 3965586.
    View in: PubMed
  33. Toth CA, Thomas P, Broitman SA, Zamcheck N. Receptor-mediated endocytosis of carcinoembryonic antigen by rat liver Kupffer cells. Cancer Res. 1985 Jan; 45(1):392-7. PMID: 2856899.
    View in: PubMed
  34. Broitman SA, Vitale JJ, Gottlieb LS. Ethanolic beverage consumption, cigarette smoking, nutritional status, and digestive tract cancers. Semin Oncol. 1983 Sep; 10(3):322-9. PMID: 6364359.
    View in: PubMed
  35. Toth CA, Thomas P, Broitman SA, Zamcheck N. A new Kupffer cell receptor mediating plasma clearance of carcinoembryonic antigen by the rat. Biochem J. 1982 May 15; 204(2):377-81. PMID: 6896821.
    View in: PubMed
  36. Vitale JJ, Broitman SA. Lipids and immune function. Cancer Res. 1981 Sep; 41(9 Pt 2):3706-10. PMID: 7260927.
    View in: PubMed
  37. Broitman SA. Cholesterol excretion and colon cancer. Cancer Res. 1981 Sep; 41(9 Pt 2):3738-40. PMID: 7260937.
    View in: PubMed
  38. Eastcott JW, Broitman SA, Bennett M. Immunogenetic differences between lymph node cell and bone marrow cell grafts in irradiated mice. Cell Immunol. 1981 Apr; 59(2):378-91. PMID: 6169445.
    View in: PubMed
  39. Eastcott JW, Broitman SA, Bennett M. Graft-versus-Host reactions by NZB lymphoid cells exposed to major or minor histocompatibility antigens in irradiated adult mice. Cell Immunol. 1981 Feb; 58(1):124-33. PMID: 7226234.
    View in: PubMed
  40. Broitman SA, Velez H, Vitale JJ. A possible role of iron deficiency in gastric cancer in Colombia. Adv Exp Med Biol. 1981; 135:155-81. PMID: 7010960.
    View in: PubMed
  41. Corwin LM, Varshavsky-Rose F, Broitman SA. Effect of dietary fats on tumorigenicity of two sarcoma cell lines. Cancer Res. 1979 Nov; 39(11):4350-5. PMID: 498068.
    View in: PubMed
  42. Shadoff N, Loria RM, Kibrick S, Broitman SA. Migration of epithelial cells in the small intestine of mice perorally infected with coxsackievirus B5. J Infect Dis. 1979 Mar; 139(3):261-6. PMID: 221595.
    View in: PubMed
  43. Katz L, LaMont JT, Trier JS, Sonnenblick EB, Rothman SW, Broitman SA, Rieth S. Experimental clindamycin-associated colitis in rabbits. Evidence of toxin-mediated mucosal damage. Gastroenterology. 1978 Feb; 74(2 Pt 1):246-52. PMID: 620897.
    View in: PubMed
  44. Loria RM, Kibrick S, Broitman SA. Pathophysiological aspects of coxsackievirus B intestinal infection. Am J Clin Nutr. 1977 Nov; 30(11):1876-9. PMID: 335868.
    View in: PubMed
  45. Broitman SA, Vitale JJ, Vavrousek-Jakuba E, Gottlieb LS. Polyunsaturated fat, cholesterol and large bowel tumorigenesis. Cancer. 1977 Nov; 40(5 Suppl):2455-63. PMID: 303539.
    View in: PubMed
  46. Vitale JJ, Broitman SA, Vavrousek-Jakuba E, Rodday PW, Gottlieb LS. The effects of iron deficiency and the quality and quantity of fat on chemically induced cancer. Adv Exp Med Biol. 1977; 91:229-42. PMID: 605850.
    View in: PubMed
  47. Loria RM, Kayne HL, Kibrick S, Broitman SA. Measurement of intestinal absorption in mice by a double-label radioisotope perfusion technic. Lab Anim Sci. 1976 Aug; 26(4):603-6. PMID: 966704.
    View in: PubMed
  48. Broitman SA, Gottlieb LS, Vitale JJ. Augmentation of ethanol absorption by mono- and disaccharides. Gastroenterology. 1976 Jun; 70(6):1101-7. PMID: 1269870.
    View in: PubMed
  49. McCabe RP, Kupchik HZ, Saravis CA, Broitman SA, Gregg JA, Zamcheck N. Demonstration and immunochemical characterization of carcinoembryonic antigen in human pancreatic juice. J Natl Cancer Inst. 1976 May; 56(5):885-9. PMID: 825652.
    View in: PubMed
  50. Loria RM, Shadoff N, Kibrick S, Broitman S. Maturation of intestinal defenses against peroral infection with group B coxsackievirus in mice. Infect Immun. 1976 May; 13(5):1397-401. PMID: 1270146.
    View in: PubMed
  51. Loria RM, Kibrick S, Broitman SA. Peroral infection with group B coxsackievirus in the adult mouse: protective functions of the gut. J Infect Dis. 1974 Nov; 130(5):539-43. PMID: 4423592.
    View in: PubMed
  52. Loria RM, Kibrick S, Broitman SA. Peroral infection with group B coxsackievirus in the newborn mouse: a model for human infection. J Infect Dis. 1974 Sep; 130(3):225-230. PMID: 4415022.
    View in: PubMed
  53. Loria RM, Kibrick S, el-Bermani al-W, Broitman SA. Preparation of intestine and other elongated specimens for histologic and immunofluorescent studies. Am J Clin Pathol. 1973 Sep; 60(3):424-7. PMID: 4580512.
    View in: PubMed
  54. Giannella RA, Broitman SA, Zamcheck N. Gastric acidity and cholera. Ann Intern Med. 1973 May; 78(5):780. PMID: 4711785.
    View in: PubMed
  55. Giannella RA, Broitman SA, Zamcheck N. Influence of gastric acidity on bacterial and parasitic enteric infections. A perspective. Ann Intern Med. 1973 Feb; 78(2):271-6. PMID: 4567180.
    View in: PubMed
  56. Simon BI, Goldman HM, Ruben MP, Broitman S, Baker E. The role of endotoxin in periodontal disease. IV. Bacteriologic analyses of human gingival exudate as related to the quantity of endotoxin and clinical degree of inflammation. J Periodontol. 1972 Aug; 43(8):468-75. PMID: 4559655.
    View in: PubMed
  57. Giannella RA, Broitman SA, Zamcheck N. Gastric acid barrier to ingested microorganisms in man: studies in vivo and in vitro. Gut. 1972 Apr; 13(4):251-6. PMID: 4556018.
    View in: PubMed
  58. Giannella RA, Broitman SA, Zamcheck N. Competition between bacteria and intrinsic factor for vitamin B 12 : implications for vitamin B 12 malabsorption in intestinal bacterial overgrowth. Gastroenterology. 1972 Feb; 62(2):255-60. PMID: 4629318.
    View in: PubMed
  59. Giannella RA, Broitman SA, Zamcheck N. Salmonella enteritis. II. Fulminant diarrhea in and effects on the small intestine. Am J Dig Dis. 1971 Nov; 16(11):1007-13. PMID: 5128594.
    View in: PubMed
  60. Giannella RA, Broitman SA, Zamcheck N. Salmonella enteritis. I. Role of reduced gastric secretion in pathogenesis. Am J Dig Dis. 1971 Nov; 16(11):1000-6. PMID: 4942816.
    View in: PubMed
  61. Giannella RA, Broitman SA, Zamcheck N. Vitamin B12 uptake by intestinal microorganisms: mechanism and relevance to syndromes of intestinal bacterial overgrowth. J Clin Invest. 1971 May; 50(5):1100-7. PMID: 4994753.
    View in: PubMed
  62. Broitman SA. Gut lactase activity: decrease during Salmonella typhimurium infection in mice. Proc Soc Exp Biol Med. 1971 Apr; 136(4):1097-9. PMID: 4928933.
    View in: PubMed
  63. Moshal MG, Broitman SA, Zamcheck N. Gastrin and absorption. A review. Am J Clin Nutr. 1970 Mar; 23(3):336-42. PMID: 4908259.
    View in: PubMed
  64. Broitman SA, McCray RS, May JC, Deren JJ, Ackroyd F, Gottlieb LS, McDermott W, Zamcheck N. Mastocytosis and intestinal malabsorption. Am J Med. 1970 Mar; 48(3):382-9. PMID: 5435650.
    View in: PubMed
  65. Zamcheck N, Wolochow DA, Winawer SJ, Broitman SA. Methodology for fecal fat quantitation in patients fed medium chain triglycerides. Gastroenterology. 1969 Feb; 56(2):386-7. PMID: 5764604.
    View in: PubMed
  66. Hoffbrand AV, Broitman SA. Effect of chronic nutritional iron deficiency on the small intestinal disaccharidase activities of growing dogs. Proc Soc Exp Biol Med. 1969 Feb; 130(2):595-8. PMID: 5765304.
    View in: PubMed
  67. Iida H, Moore EW, Broitman SA, Zamcheck N. Effect of pH on active transport of d-glucose in the small intestine of hamsters. Proc Soc Exp Biol Med. 1968 Mar; 127(3):730-2. PMID: 5651124.
    View in: PubMed
  68. Bejar J, Broitman SA, Zamcheck N. Effect of vagotomy upon the small intestine. Gut. 1968 Feb; 9(1):87-90. PMID: 5640932.
    View in: PubMed
  69. Winawer SJ, Herskovic T, Goldsmith R, Broitman SA, Zamcheck N. Albumin survival in patients with massive small-bowel resection. Am J Dig Dis. 1967 Aug; 12(8):753-60. PMID: 4951377.
    View in: PubMed
  70. Broitman SA, Flint D, Zamcheck N. Neomycin feeding in the rat: studies of intestinal absorption of glucose and xylose. J Lab Clin Med. 1967 Jul; 70(1):9-15. PMID: 6027099.
    View in: PubMed
  71. Deren JJ, Broitman SA, Zamcheck N. Effect of diet upon intestinal disaccharidases and disaccharide absorption. J Clin Invest. 1967 Feb; 46(2):186-95. PMID: 6018758.
    View in: PubMed
  72. Winawer SJ, Broitman SA, Wolochow DA, Osborne MP, Zamcheck N. Successful management of massive small-bowel resection based on assessment of absorption defects and nutritional needs. N Engl J Med. 1966 Jan 13; 274(2):72-8. PMID: 5901206.
    View in: PubMed
  73. WOLOCHOW DA, BROITMAN SA, WILLIAMS LA, ZAMCHECK N. A RAPID METHOD FOR QUANTITATIVE DETERMINATION OF FECAL FAT BASED ON THE PRINCIPLE OF ELECTRICAL CAPACITANCE. J Lab Clin Med. 1965 Feb; 65:334-41. PMID: 14267258.
    View in: PubMed
  74. WINAWER SJ, BROITMAN SA, GOTTLIEB LS, ZAMCHECK N. THE SERUM AND LIVER AMYLASE AND TRANSAMINASE ACTIVITIES IN CHOLINE DEFICIENCY FATTY LIVER AND CIRRHOSIS. Gastroenterology. 1965 Feb; 48:216-25. PMID: 14257479.
    View in: PubMed
  75. BROITMAN SA, GOTTLIEB LS, ZAMCHECK N. INFLUENCE OF NEOMYCIN AND INGESTED ENDOTOXIN IN THE PATHOGENESIS OF CHOLINE DEFICIENCY CIRRHOSIS IN THE ADULT RAT. J Exp Med. 1964 Apr 1; 119:633-42. PMID: 14151103.
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  76. BROITMAN SA, BONDY DC, YACHNIN I, HOSKINS LC, INGBAR S, ZAMCHECK N. ABSORPTION AND DISPOSITION OF D-XYLOSE IN THYROTOXICOSIS AND MYXEDEMA. N Engl J Med. 1964 Feb 13; 270:333-7. PMID: 14085591.
    View in: PubMed
  77. JACOBSON ED, BONDY DC, BROITMAN SA, FORDTRAN JS. Validity of polyethylene glycol in estimating intestinal water volume. Gastroenterology. 1963 Jun; 44:761-7. PMID: 13964348.
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  78. BROITMAN SA, ZAMCHECK N. Utilization and excretion of D-xylose in thyroxine-treated rats. J Lab Clin Med. 1963 Mar; 61:476-82. PMID: 14015734.
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  79. GOTTLIEB LS, BROITMAN SA, VITALE JJ, ZAMCHECK W. Failure of endogenous serotonin to produce lesions of the carcinoid syndrome. Studies on mouse mastocytoma. Arch Pathol. 1960 Jan; 69:77-81. PMID: 13851440.
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  80. BROITMAN SA, KINNEAR DG, GOTTLIEB LS, BEZMAN AL, VITALE JJ, ZAMCHECK N. Effect of neomycin alteration of the rat intestinal flora on serum cholesterol and valvular sudanophilia. J Lab Clin Med. 1960 Jan; 55:55-9. PMID: 13804701.
    View in: PubMed
  81. BROITMAN SA, BEZMAN AL, HAZEL MM, ZAMCHECK N. Effect of endotoxin on gastrointestinal mucosa of the rat. Proc Soc Exp Biol Med. 1959 Mar; 100(3):557-61. PMID: 13634207.
    View in: PubMed
  82. GOTTLIEB LS, BROITMAN SA, VITALE JJ, ZAMCHECK N. The influence of alcohol and dietary magnesium upon hypercholesterolemia and atherogenesis in the rat. J Lab Clin Med. 1959 Mar; 53(3):433-41. PMID: 13631326.
    View in: PubMed
  83. NAKAMURA M, PICHETTE P, BROITMAN S, BEZMAN AL, ZAMCHECK N, VITALE JJ. Studies on the inhibitory effect of intestinal mucosa of succinoxidase activity. J Biol Chem. 1959 Jan; 234(1):206-10. PMID: 13610922.
    View in: PubMed
  84. MALLMANN WL, BROITMAN SA. A surface plating technic for determining bacterial population of milk. Am J Public Health Nations Health. 1956 Aug; 46(8):1018-20. PMID: 13340043.
    View in: PubMed
  85. BROITMAN SA, COHEN JR, LITSKY W. A comparison of the effects of Terramycin hydrochloride and amphoteric Terramycin on the fecal flora of humans. Am J Med Sci. 1953 Oct; 226(4):419-24. PMID: 13092103.
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  86. BROITMAN SA, COHEN JR. A simple colony counter. Am J Med Technol. 1953 May-Jun; 19(3):150-1. PMID: 13057872.
    View in: PubMed
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