Keywords
Last Name

Ryota Kikuchi, DMD

TitleClinical Assistant Professor
InstitutionBoston University Henry M. Goldman School of Dental Medicine
DepartmentGeneral Dentistry
Address100 E. Newton St Goldman SDM
Boston MA 02118
Phone(617) 414-1060
ORCID ORCID Icon0000-0002-8839-2891
Other Positions
TitlePractice Leader, Pre-doctoral Patient Treatment Center
InstitutionBoston University Henry M. Goldman School of Dental Medicine
DepartmentDiagnostic Sciences & Patient Services
DivisionSDM Group Practice

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Tsuji T, Yamaguchi K, Kikuchi R, Nakamura H, Misaka R, Nagai A, Aoshiba K. Improvement of metabolic disorders by an EP2 receptor agonist via restoration of the subcutaneous adipose tissue in pulmonary emphysema. Prostaglandins Other Lipid Mediat. 2017 Mar 02; 130:16-22. PMID: 28263859.
    View in: PubMed
  2. Kikuchi R, Itoh M, Tamamushi M, Nakamura H, Aoshiba K. Hypertrophic Osteoarthropathy Secondary to Lung Cancer: Beneficial Effect of Anti-vascular Endothelial Growth Factor Antibody. J Clin Rheumatol. 2017 Jan; 23(1):47-50. PMID: 28002159.
    View in: PubMed
  3. Kikuchi R, Mizuta K, Urahashi T, Sanada Y, Yamada N, Onuma E, Ono M, Endo M, Sato I, Kamibeppu K. Development of the Japanese version of the Pediatric Quality of Life Inventory™ Transplant Module. Pediatr Int. 2017 Jan; 59(1):80-88. PMID: 27278923.
    View in: PubMed
  4. Kikuchi R, Peterkin VC, Chiou WJ, de Morais SM, Bow DA. Validation of a total IC50 method which enables in vitro assessment of transporter inhibition under semi-physiological conditions. Xenobiotica. 2016 Oct 03; 1-8. PMID: 27609543.
    View in: PubMed
  5. Watanabe O, Tsuji T, Kikuchi R, Itoh M, Nakamura H, Aoshiba K. Little evidence for epithelial-mesenchymal transition in a murine model of airway fibrosis induced by repeated naphthalene exposure. Exp Toxicol Pathol. 2016 Oct; 68(9):517-520. PMID: 27498952.
    View in: PubMed
  6. Watanabe H, Uruma T, Seita I, Chikasawa Y, Kikuchi R, Itoh M, Aoshiba K, Nakamura H, Oishi T. Successful desensitization therapy involving fluoroquinolone for the treatment of a solitary tuberculoma: A case report and literature review. Mol Clin Oncol. 2016 Jul; 5(1):117-120. PMID: 27330780.
    View in: PubMed
  7. Kikuchi R, Aoshiba K, Nakamura H. Salivary Gland Enlargement as an Unusual Imaging Manifestation of Granulomatosis With Polyangiitis Involving the Head and Neck Region. AJR Am J Roentgenol. 2016 Jun; 206(6):W94. PMID: 26998726.
    View in: PubMed
  8. Watanabe H, Uruma T, Tazaki G, Tajiri T, Kikuchi R, Itoh M, Aoshiba K, Nakamura H. Remission of ALK-negative primary pulmonary inflammatory myofibroblastic tumor on treatment with clarithromycin: A case report and review of the literature. Oncol Lett. 2016 Mar; 11(3):1757-1761. PMID: 26998073.
    View in: PubMed
  9. Kikuchi R, Itoh M, Uruma T, Tsuji T, Watanabe H, Nakamura H, Aoshiba K. Diffuse alveolar hemorrhage after use of a fluoropolymer-based waterproofing spray. Springerplus. 2015; 4:270. PMID: 26090317.
    View in: PubMed
  10. Tsuji T, Itoh M, Kikuchi R, Uruma T, Watanabe H, Yamaguchi K, Nakamura H, Aoshiba K. Repeated exposure to 5-bromo-2'-deoxyuridine causes decreased proliferation and low-grade inflammation in the lungs of mice. Exp Toxicol Pathol. 2015 May-Jun; 67(5-6):355-60. PMID: 25911309.
    View in: PubMed
  11. Kikuchi R, Ono M, Kinugawa K, Endo M, Mizuta K, Urahashi T, Ihara Y, Yoshida S, Ito S, Kamibeppu K. Health-related quality of life in parents of pediatric solid organ transplant recipients in Japan. Pediatr Transplant. 2015 May; 19(3):332-41. PMID: 25651866.
    View in: PubMed
  12. Watanabe H, Uruma T, Tazaki G, Kikuchi R, Tsuji T, Itoh M. Clinical factors associated with negative urinary antigen tests implemented for the diagnosis of community-acquired pneumococcal pneumonia in adult patients. Med Princ Pract. 2015; 24(2):189-94. PMID: 25613456.
    View in: PubMed
  13. Kikuchi R, Kamibeppu K. Parents' quality of life and family functioning in pediatric organ transplantation. J Pediatr Nurs. 2015 May-Jun; 30(3):463-77. PMID: 25605616.
    View in: PubMed
  14. Itoh M, Kikuchi R, Uruma T, Tsuji T, Kuroda Y, Watanabe H, Nakamura H, Aoshiba K. All-in-one imaging of polymyositis, lung cancer and its metastatic lesions by fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography. Acta Reumatol Port. 2014 Jul-Sep; 39(3):283-4. PMID: 25326410.
    View in: PubMed
  15. Tsuji T, Yamaguchi K, Kikuchi R, Itoh M, Nakamura H, Nagai A, Aoshiba K. Promotion of adipogenesis by an EP2 receptor agonist via stimulation of angiogenesis in pulmonary emphysema. Prostaglandins Other Lipid Mediat. 2014 Aug; 112:9-15. PMID: 24911647.
    View in: PubMed
  16. Tsuji T, Kondo M, Kikuchi R, Tagaya E, Tamaoki J. A case of eosinophilic pneumonia simultaneously diagnosed in a patient and a tame cat: a case report. J Med Case Rep. 2014; 8(1):83. PMID: 24594228.
    View in: PubMed
  17. Kikuchi R, Lao Y, Bow DA, Chiou WJ, Andracki ME, Carr RA, Voorman RL, De Morais SM. Prediction of clinical drug-drug interactions of veliparib (ABT-888) with human renal transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K). J Pharm Sci. 2013 Dec; 102(12):4426-32. PMID: 24122511.
    View in: PubMed
  18. Kikuchi R, de Morais SM, Kalvass JC. In vitro P-glycoprotein efflux ratio can predict the in vivo brain penetration regardless of biopharmaceutics drug disposition classification system class. Drug Metab Dispos. 2013 Dec; 41(12):2012-7. PMID: 24009309.
    View in: PubMed
  19. Chiou WJ, de Morais SM, Kikuchi R, Voorman RL, Li X, Bow DA. In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia. Xenobiotica. 2014 Mar; 44(3):276-82. PMID: 23886114.
    View in: PubMed
  20. Imai S, Kikuchi R, Tsuruya Y, Naoi S, Nishida S, Kusuhara H, Sugiyama Y. Epigenetic regulation of organic anion transporting polypeptide 1B3 in cancer cell lines. Pharm Res. 2013 Nov; 30(11):2880-90. PMID: 23812637.
    View in: PubMed
  21. Imai S, Kikuchi R, Kusuhara H, Sugiyama Y. DNA methylation and histone modification profiles of mouse organic anion transporting polypeptides. Drug Metab Dispos. 2013 Jan; 41(1):72-8. PMID: 23033256.
    View in: PubMed
  22. Jin L, Kikuchi R, Saji T, Kusuhara H, Sugiyama Y. Regulation of tissue-specific expression of renal organic anion transporters by hepatocyte nuclear factor 1 a/ß and DNA methylation. J Pharmacol Exp Ther. 2012 Mar; 340(3):648-55. PMID: 22160269.
    View in: PubMed
  23. Kikuchi R, McCown M, Olson P, Tateno C, Morikawa Y, Katoh Y, Bourdet DL, Monshouwer M, Fretland AJ. Effect of hepatitis C virus infection on the mRNA expression of drug transporters and cytochrome p450 enzymes in chimeric mice with humanized liver. Drug Metab Dispos. 2010 Nov; 38(11):1954-61. PMID: 20693416.
    View in: PubMed
  24. Kikuchi R, Yagi S, Kusuhara H, Imai S, Sugiyama Y, Shiota K. Genome-wide analysis of epigenetic signatures for kidney-specific transporters. Kidney Int. 2010 Sep; 78(6):569-77. PMID: 20555317.
    View in: PubMed
  25. Ichihara S, Kikuchi R, Kusuhara H, Imai S, Maeda K, Sugiyama Y. DNA methylation profiles of organic anion transporting polypeptide 1B3 in cancer cell lines. Pharm Res. 2010 Mar; 27(3):510-6. PMID: 20130966.
    View in: PubMed
  26. Imai S, Kikuchi R, Kusuhara H, Yagi S, Shiota K, Sugiyama Y. Analysis of DNA methylation and histone modification profiles of liver-specific transporters. Mol Pharmacol. 2009 Mar; 75(3):568-76. PMID: 19047482.
    View in: PubMed
  27. Sekine K, Takubo K, Kikuchi R, Nishimoto M, Kitagawa M, Abe F, Nishikawa K, Tsuruo T, Naito M. Small molecules destabilize cIAP1 by activating auto-ubiquitylation. J Biol Chem. 2008 Apr 4; 283(14):8961-8. PMID: 18230607.
    View in: PubMed
  28. Saji T, Kikuchi R, Kusuhara H, Kim I, Gonzalez FJ, Sugiyama Y. Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/beta. J Pharmacol Exp Ther. 2008 Feb; 324(2):784-90. PMID: 18029548.
    View in: PubMed
  29. Gomi K, Miki M, Itabashi S, Kikuchi T, Miur S, Shikanai T, Inoue H, Takeuchi K, Kanda A, Suzukio S, Nakagawa H, Hommma M, Miki H, Abe T, Nishimaki K, Saito H, Yasugahir H, Sayam T, Sat M, Kikuchi R, Honda Y, Kawan A, Watanabe A. [Results of a survey of community-acquired-pneumonia and evaluation of old and new Japanese Respiratory Society guidelines]. Nihon Kokyuki Gakkai Zasshi. 2007 Nov; 45(11):836-43. PMID: 18051784.
    View in: PubMed
  30. Kikuchi R, Kusuhara H, Hattori N, Kim I, Shiota K, Gonzalez FJ, Sugiyama Y. Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation. Mol Pharmacol. 2007 Dec; 72(6):1619-25. PMID: 17855651.
    View in: PubMed
  31. Ishioka T, Katayama R, Kikuchi R, Nishimoto M, Takada S, Takada R, Matsuzawa S, Reed JC, Tsuruo T, Naito M. Impairment of the ubiquitin-proteasome system by cellular FLIP. Genes Cells. 2007 Jun; 12(6):735-44. PMID: 17573774.
    View in: PubMed
  32. Kikuchi R, Kusuhara H, Hattori N, Shiota K, Kim I, Gonzalez FJ, Sugiyama Y. Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation. Mol Pharmacol. 2006 Sep; 70(3):887-96. PMID: 16793932.
    View in: PubMed
  33. Kikuchi R, Kusuhara H, Abe T, Endou H, Sugiyama Y. Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors across the blood-brain barrier. J Pharmacol Exp Ther. 2004 Dec; 311(3):1147-53. PMID: 15292460.
    View in: PubMed
  34. Kikuchi R, Kusuhara H, Sugiyama D, Sugiyama Y. Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier. J Pharmacol Exp Ther. 2003 Jul; 306(1):51-8. PMID: 12684544.
    View in: PubMed
  35. Yoshimura K, Fujii J, Yutsudo T, Kikuchi R, Soejima T, Shirahata S, Yoshida S. No direct effects of Shiga toxin 1 and 2 on the aggregation of human platelets in vitro. Thromb Haemost. 1998 Sep; 80(3):529-30. PMID: 9759646.
    View in: PubMed
  36. Kikuchi R, Watabe N, Konno T, Mishina N, Sekizawa K, Sasaki H. High incidence of silent aspiration in elderly patients with community-acquired pneumonia. Am J Respir Crit Care Med. 1994 Jul; 150(1):251-3. PMID: 8025758.
    View in: PubMed
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