Melanie Brennan
Pre-Doctoral Trainee
Boston University School of Medicine, Division of Graduate Medical Sciences
Dept of Neuroscience

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Brennan MS, Matos MF, Richter KE, Li B, Scannevin RH. The NRF2 transcriptional target, OSGIN1, contributes to monomethyl fumarate-mediated cytoprotection in human astrocytes. Sci Rep. 2017 Feb 09; 7:42054. PMID: 28181536; DOI: 10.1038/srep42054;.
  2. Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, Brennan MS, Quintero-Monzon O, Scannevin RH, Arnold HM, Engber T, Rhodes K, Ferrero J, Hang Y, Mikulskis A, Grimm J, Hock C, Nitsch RM, Sandrock A. The antibody aducanumab reduces Aß plaques in Alzheimer''s disease. Nature. 2016; 537(7618):50-6. PMID: 27582220; DOI: 10.1038/nature19323;.
  3. Brennan MS, Patel H, Allaire N, Thai A, Cullen P, Ryan S, Lukashev M, Bista P, Huang R, Rhodes KJ, Scannevin RH. Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms. Antioxid Redox Signal. 2016 Jun 20; 24(18):1058-71. PMID: 26980071; DOI: 10.1089/ars.2015.6622;.
  4. Scannevin RH, Chollate S, Brennan MS, Snodgrass-Belt PA, Peng H, Xu L, Jung MY, Bussiere T, Arastu MF, Talreja T, Xin Z, Dunstan RW, Fahrer D, Rohde E, Dunah AW, Wang J, Kumaravel G, Taveras AG, Moore Arnold H, Rhodes KJ. BIIB042, a novel ?-secretase modulator, reduces amyloidogenic Aß isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer''s disease. Neuropharmacology. 2016 Apr; 103:57-68. PMID: 26690893; DOI: 10.1016/j.neuropharm.2015.12.006;.
  5. Brennan MS, Matos MF, Li B, Hronowski X, Gao B, Juhasz P, Rhodes KJ, Scannevin RH. Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitro. PLoS One. 2015; 10(3):e0120254. PMID: 25793262; PMCID: PMC4368598; DOI: 10.1371/journal.pone.0120254;.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 5 publications over 3 distinct years, with a maximum of 2 publications in 2015 and 2016

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