Keywords
Last Name

Laertis Ikonomou, PhD

TitleAssistant Professor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionPulmonary, Allergy, Sleep & Critical Care Medicine
Address72 E. Concord St Housman (R)
Boston MA 02118
Phone(617) 638-4860
ORCID ORCID Icon0000-0003-0993-6713
Other Positions
TitleCenter Faculty Member
InstitutionBoston University School of Medicine
DepartmentCenter for Regenerative Medicine

 Research Expertise & Professional Interests
Research interests include:
-Lung developmental biology
-Lung Epithelial Lineage Specification
-Development of new platforms for stem cell expansion and differentiation

 Self-Described Keywords
  • Embryonic stem cells
  • Lung Developmental Biology
  • Stem Cell Engineering
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Ikonomou L, Freishtat RJ, Wagner DE, Panoskaltsis-Mortari A, Weiss DJ. The Global Emergence of Unregulated Stem Cell Treatments for Respiratory Diseases. Professional Societies Need to Act. Ann Am Thorac Soc. 2016 Aug; 13(8):1205-7. PMID: 27509147.
    View in: PubMed
  2. Kurmann AA, Serra M, Hawkins F, Rankin SA, Mori M, Astapova I, Ullas S, Lin S, Bilodeau M, Rossant J, Jean JC, Ikonomou L, Deterding RR, Shannon JM, Zorn AM, Hollenberg AN, Kotton DN. Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells. Cell Stem Cell. 2015 Nov 5; 17(5):527-42. PMID: 26593959.
    View in: PubMed
  3. Ikonomou L, Kotton DN. Derivation of Endodermal Progenitors From Pluripotent Stem Cells. J Cell Physiol. 2015 Feb; 230(2):246-58. PMID: 25160562.
    View in: PubMed
  4. Longmire TA, Ikonomou L, Kotton DN. Mouse ESC Differentiation to Nkx2.1+ Lung and Thyroid Progenitors. Bio Protoc. 2012 Nov 20; 2(22). PMID: 27453901.
    View in: PubMed
  5. Longmire TA, Ikonomou L, Hawkins F, Christodoulou C, Cao Y, Jean JC, Kwok LW, Mou H, Rajagopal J, Shen SS, Dowton AA, Serra M, Weiss DJ, Green MD, Snoeck HW, Ramirez MI, Kotton DN. Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells. Cell Stem Cell. 2012 Apr 6; 10(4):398-411. PMID: 22482505.
    View in: PubMed
  6. Diaz PI, Xie Z, Sobue T, Thompson A, Biyikoglu B, Ricker A, Ikonomou L, Dongari-Bagtzoglou A. Synergistic interaction between Candida albicans and commensal oral streptococci in a novel in vitro mucosal model. Infect Immun. 2012 Feb; 80(2):620-32. PMID: 22104105.
    View in: PubMed
  7. Ikonomou L, Hemnes AR, Bilousova G, Hamid R, Loyd JE, Hatzopoulos AK, Kotton DN, Majka SM, Austin ED. Programmatic change: lung disease research in the era of induced pluripotency. Am J Physiol Lung Cell Mol Physiol. 2011 Dec; 301(6):L830-5. PMID: 21984571.
    View in: PubMed
  8. Kotova S, Vijayasarathy C, Dimitriadis EK, Ikonomou L, Jaffe H, Sieving PA. Retinoschisin (RS1) interacts with negatively charged lipid bilayers in the presence of Ca2+: an atomic force microscopy study. Biochemistry. 2010 Aug 24; 49(33):7023-32. PMID: 20677810.
    View in: PubMed
  9. Ott HC, Clippinger B, Conrad C, Schuetz C, Pomerantseva I, Ikonomou L, Kotton D, Vacanti JP. Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med. 2010 Aug; 16(8):927-33. PMID: 20628374.
    View in: PubMed
  10. Lenas P, Saravia V, Toca-Herrera JL, Paternain JL, Ikonomou L, Mayer J, Probst I, Crawford J, Vassilicos JC, Moreno A, Dravaliari A, Kolodkin A, Guzmán-Aránguez A, Pintor J. Biomimetics in Biophysics: Model systems, experimental techniques and computation. Functional biomimetics in tissue engineering: engineering emergent tissue functions in vitro through complexity and networks science. Research Signpost. Kerala, India. 2010; 153-192.
  11. Lenas P, Luyten FP, Saravia V, Toca-Herrera JL, Ikonomou L, Nicodemou-Lena E, Ito A, Honda H, Dinnyes A, Mayer J, Arzimanoglou I, Gordillo FM, Guzmán-Aránguez A, Pintor J. Biomimetics in Biophysics: Model systems, experimental techniques and computation. Process biomimetics in tissue engineering: engineering the in vitro tissue development through systems biology and networks science. Research Signpost. Kerala, India. 2010; 193-225.
  12. Davani B, Ariely S, Ikonomou L, Oron Y, Gershengorn MC. Human islet-derived precursor cells can cycle between epithelial clusters and mesenchymal phenotypes. J Cell Mol Med. 2009 Aug; 13(8B):2570-81. PMID: 19175683.
    View in: PubMed
  13. Lenas P, Moreno A, Ikonomou L, Mayer J, Honda H, Novellino A, Pizarro C, Nicodemou-Lena E, Rodergas S, Pintor J. The complementarity of the technical tools of tissue engineering and the concepts of artificial organs for the design of functional bioartificial tissues. Artif Organs. 2008 Sep; 32(9):742-7. PMID: 18684202.
    View in: PubMed
  14. Ikonomou L, Geras-Raaka E, Raaka BM, Gershengorn MC. Beta-catenin signalling in mesenchymal islet-derived precursor cells. Cell Prolif. 2008 Jun; 41(3):474-91. PMID: 18422699.
    View in: PubMed
  15. Davani B, Ikonomou L, Raaka BM, Geras-Raaka E, Morton RA, Marcus-Samuels B, Gershengorn MC. Human islet-derived precursor cells are mesenchymal stromal cells that differentiate and mature to hormone-expressing cells in vivo. Stem Cells. 2007 Dec; 25(12):3215-22. PMID: 17901402.
    View in: PubMed
  16. Ikonomou L, Bastin G, Schneider YJ, Agathos SN. Effect of Partial Medium Replacement on Cell Growth and Protein Production for the High-Fivetrade mark insect cell line. Cytotechnology. 2004 Jan; 44(1-2):67-76. PMID: 19003230.
    View in: PubMed
  17. Ikonomou L, Schneider YJ, Agathos SN. Insect cell culture for industrial production of recombinant proteins. Appl Microbiol Biotechnol. 2003 Jul; 62(1):1-20. PMID: 12733003.
    View in: PubMed
  18. Ikonomou L, Drugmand JC, Bastin G, Schneider YJ, Agathos SN. Microcarrier culture of lepidopteran cell lines: implications for growth and recombinant protein production. Biotechnol Prog. 2002 Nov-Dec; 18(6):1345-55. PMID: 12467471.
    View in: PubMed
  19. Ikonomou L, Bastin G, Schneider YJ, Agathos SN. Design of an efficient medium for insect cell growth and recombinant protein production. In Vitro Cell Dev Biol Anim. 2001 Oct; 37(9):549-59. PMID: 11710429.
    View in: PubMed
  20. Drugmand J-C, Ikonomou L, Schneider Y-J, Agathos SN. Growth of High-FiveTM cells on Cultispher-S microcarriers. In: Lindner-Olsson E, Chatzissavidou N and Lüllau E (eds.) Animal Cell Technology: From Target to Market. Kluwer Academic Publishers. Dordrecht. 2001; 332-334.
  21. Ikonomou L, Drugmand J-C, Bastin G, Schneider Y-J, Agathos SN. Physiology of insect cells cultured in a new serum-free medium. In: Lindner-Olsson E, Chatzissavidou N and Lüllau E (eds.) Animal Cell Technology: From Target to Market. Kluwer Academic Publishers. Dordrecht. 2001; 338-340.
  22. Ikonomou L, Bastin L, Schneider Y-J, Agathos SN. Growth on microcarriers and nutritional needs of high density insect cell cultures. In: Bernard A., Griffiths B., Noé W. and Wurm F. (eds.) Animal cell technology: Products from cells, cells as products. Kluwer Academic Publishers. Dordrecht. 1999; 371-373.
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