Konstantin Balashov

Clinical Professor

Boston University Chobanian & Avedisian School of Medicine

Neurology

MD, Russian State Medical University
PhD, Russian Academy of Medical Sciences

Websites

	Boston Medical Center
	BUMC
	Linkedin
	Research Gate

ORCID : 0000-0003-3409-8731

BMC Research

Treatment Access and Outcomes by Gender, Race and Socio-Economic Status in Multiple Sclerosis Patients: Real World Investigation
07/01/2023 - 06/30/2024 (PI)
Brigham and Womens Hospital Genentech, Inc.

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Yadav SK, Ito N, Mindur JE, Kumar H, Youssef M, Suresh S, Kulkarni R, Rosario Y, Balashov KE, Dhib-Jalbut S, Ito K. Fecal Lcn-2 level is a sensitive biological indicator for gut dysbiosis and intestinal inflammation in multiple sclerosis. Front Immunol. 2022; 13:1015372. PMID: 36341389; PMCID: PMC9634083; DOI: 10.3389/fimmu.2022.1015372;

Balashov K, Dhib-Jalbut S, Rybinnik I. Fibrinolysis induced clinical improvement in a patient with multiple sclerosis exacerbation. Mult Scler Relat Disord. 2020 Aug; 43:102225. PMID: 32505025

Balashov K. Imaging of Central Nervous System Demyelinating Disorders. Continuum (Minneap Minn). 2016 Oct; 22(5, Neuroimaging):1613-1635. PMID: 27740991

Valenzuela RM, Kaufman M, Balashov KE, Ito K, Buyske S, Dhib-Jalbut S. Predictive cytokine biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis. J Neuroimmunol. 2016 11 15; 300:59-65. PMID: 27390072; DOI: 10.1016/j.jneuroim.2016.06.005;

Bhise, V., Balashov, K., Sturgill, M., Krupp, L., Dhib-Jalbut, S. Cytokine profiles in pediatric multiple sclerosis. Multiple Sclerosis and Demyelinating Disorders. 2016.
Bhise, V., Buyukturkoglu, K., Inglese, M., Wollack, J.B. and K. Balashov. Severe Progressive Brain Atrophy in Pediatric Multiple Sclerosis. J Pediatr Neuroradiol. 2015.
Sobol, I., Sobol, M., and K.E. Balashov. Cardiac arrhythmia with premature ventricular contractures induced by interferon beta in a patient with multiple sclerosis. Neuroimmunology and Neuroinflammation. 2015.

Aung LL, Balashov KE. Decreased Dicer expression is linked to increased expression of co-stimulatory molecule CD80 on B cells in multiple sclerosis. Mult Scler. 2015 Aug; 21(9):1131-8. PMID: 25480859; PMCID: PMC4457720; DOI: 10.1177/1352458514560923;

Aung LL, Mouradian MM, Dhib-Jalbut S, Balashov KE. MMP-9 expression is increased in B lymphocytes during multiple sclerosis exacerbation and is regulated by microRNA-320a. J Neuroimmunol. 2015 Jan 15; 278:185-9. PMID: 25468268; PMCID: PMC4297694; DOI: 10.1016/j.jneuroim.2014.11.004;

Boppana S, Mindur JE, Balashov KE, Dhib-Jalbut S, Ito K. Comparison of IFN-ß inducible gene expression in primary-progressive and relapsing-remitting multiple sclerosis. J Neuroimmunol. 2013 Dec 15; 265(1-2):68-74. PMID: 24200257

Showing 10 of 51 results. Show More

Casini G, Yurashevich M, Vanga R, Dash S, Dhib-Jalbut S, Gerhardstein B, Inglese M, Toe W, Balashov KE. Are Periventricular Lesions Specific for Multiple Sclerosis? J Neurol Neurophysiol. 2013 May 03; 4(2):150. PMID: 25568815; PMCID: PMC4283830; DOI: 10.4172/2155-9562.1000150;

von Glehn F, Santos LM, Balashov KE. Plasmacytoid dendritic cells and immunotherapy in multiple sclerosis. Immunotherapy. 2012 Oct; 4(10):1053-61. PMID: 23148757; PMCID: PMC3556815; DOI: 10.2217/imt.12.117;

Aung LL, Brooks A, Greenberg SA, Rosenberg ML, Dhib-Jalbut S, Balashov KE. Multiple sclerosis-linked and interferon-beta-regulated gene expression in plasmacytoid dendritic cells. J Neuroimmunol. 2012 Sep 15; 250(1-2):99-105. PMID: 22688425; PMCID: PMC3418446; DOI: 10.1016/j.jneuroim.2012.05.013;

Balashov KE, Lindzen E. Acute demyelinating lesions with restricted diffusion in multiple sclerosis. Mult Scler. 2012 Dec; 18(12):1745-53. PMID: 22523157; PMCID: PMC3576471; DOI: 10.1177/1352458512445407;

Soni, P., Dash, S., Balashov, K. . Lyme Neuroborreliosis can mimic stroke-in-progression. Int J Cur Sci Res. 2012.

Balashov KE, Aung LL, Dhib-Jalbut S, Keller IA. Acute multiple sclerosis lesion: conversion of restricted diffusion due to vasogenic edema. J Neuroimaging. 2011 Apr; 21(2):202-4. PMID: 19888931; PMCID: PMC2891920; DOI: 10.1111/j.1552-6569.2009.00443.x;

Longhini AL, von Glehn F, Brandão CO, de Paula RF, Pradella F, Moraes AS, Farias AS, Oliveira EC, Quispe-Cabanillas JG, Abreu CH, Damasceno A, Damasceno BP, Balashov KE, Santos LM. Plasmacytoid dendritic cells are increased in cerebrospinal fluid of untreated patients during multiple sclerosis relapse. J Neuroinflammation. 2011 Jan 07; 8(1):2. PMID: 21214939; PMCID: PMC3022734; DOI: 10.1186/1742-2094-8-2;

Balashov KE, Aung LL, Vaknin-Dembinsky A, Dhib-Jalbut S, Weiner HL. Interferon-ß inhibits toll-like receptor 9 processing in multiple sclerosis. Ann Neurol. 2010 Dec; 68(6):899-906. PMID: 21061396; PMCID: PMC3058378; DOI: 10.1002/ana.22136;

Aung LL, Fitzgerald-Bocarsly P, Dhib-Jalbut S, Balashov K. Plasmacytoid dendritic cells in multiple sclerosis: chemokine and chemokine receptor modulation by interferon-beta. J Neuroimmunol. 2010 Sep 14; 226(1-2):158-64. PMID: 20621365; PMCID: PMC2937086; DOI: 10.1016/j.jneuroim.2010.06.008;

Meier DS, Balashov KE, Healy B, Weiner HL, Guttmann CR. Seasonal prevalence of MS disease activity. Neurology. 2010 Aug 31; 75(9):799-806. PMID: 20805526; PMCID: PMC2938966; DOI: 10.1212/WNL.0b013e3181f0734c;

Balashov KE, Pal G, Rosenberg ML. Optic neuritis incidence is increased in spring months in patients with asymptomatic demyelinating lesions. Mult Scler. 2010 Feb; 16(2):252-4. PMID: 20142310; PMCID: PMC2861653; DOI: 10.1177/1352458509355070;

Vaknin-Dembinsky A, Balashov K, Weiner HL. IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol. 2006 Jun 15; 176(12):7768-74. PMID: 16751425

Karni A, Balashov K, Hancock WW, Bharanidharan P, Abraham M, Khoury SJ, Weiner HL. Cyclophosphamide modulates CD4+ T cells into a T helper type 2 phenotype and reverses increased IFN-gamma production of CD8+ T cells in secondary progressive multiple sclerosis. J Neuroimmunol. 2004 Jan; 146(1-2):189-98. PMID: 14698862

Balashov KE, Comabella M, Ohashi T, Khoury SJ, Weiner HL. Defective regulation of IFNgamma and IL-12 by endogenous IL-10 in progressive MS. Neurology. 2000 Jul 25; 55(2):192-8. PMID: 10908889; DOI: 10.1212/wnl.55.2.192;

Balashov KE, Rottman JB, Weiner HL, Hancock WW. CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions. Proc Natl Acad Sci U S A. 1999 Jun 08; 96(12):6873-8. PMID: 10359806; PMCID: PMC22009; DOI: 10.1073/pnas.96.12.6873;

Windhagen A, Anderson DE, Carrizosa A, Balashov K, Weiner HL, Hafler DA. Cytokine secretion of myelin basic protein reactive T cells in patients with multiple sclerosis. J Neuroimmunol. 1998 Nov 02; 91(1-2):1-9. PMID: 9846813; DOI: 10.1016/s0165-5728(98)00086-1;

Balashov KE, Olek MJ, Smith DR, Khoury SJ, Weiner HL. Seasonal variation of interferon-gamma production in progressive multiple sclerosis. Ann Neurol. 1998 Nov; 44(5):824-8. PMID: 9818941; DOI: 10.1002/ana.410440519;

Comabella M, Balashov K, Issazadeh S, Smith D, Weiner HL, Khoury SJ. Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy. J Clin Invest. 1998 Aug 15; 102(4):671-8. PMID: 9710434; PMCID: PMC508928; DOI: 10.1172/JCI3125;

Pohl-Koppe A, Balashov KE, Steere AC, Logigian EL, Hafler DA. Identification of a T cell subset capable of both IFN-gamma and IL-10 secretion in patients with chronic Borrelia burgdorferi infection. J Immunol. 1998 Feb 15; 160(4):1804-10. PMID: 9469440

Smith DR, Balashov KE, Hafler DA, Khoury SJ, Weiner HL. Immune deviation following pulse cyclophosphamide/methylprednisolone treatment of multiple sclerosis: increased interleukin-4 production and associated eosinophilia. Ann Neurol. 1997 Sep; 42(3):313-8. PMID: 9307252; DOI: 10.1002/ana.410420307;

Balashov KE, Smith DR, Khoury SJ, Hafler DA, Weiner HL. Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand. Proc Natl Acad Sci U S A. 1997 Jan 21; 94(2):599-603. PMID: 9012830; PMCID: PMC19559; DOI: 10.1073/pnas.94.2.599;

Balashov KE, Khoury SJ, Hafler DA, Weiner HL. Inhibition of T cell responses by activated human CD8+ T cells is mediated by interferon-gamma and is defective in chronic progressive multiple sclerosis. J Clin Invest. 1995 Jun; 95(6):2711-9. PMID: 7769110; PMCID: PMC295954; DOI: 10.1172/JCI117973;

Balashov KE, Brondz BD. Application of anti-CD3-treated lymphocytes as stimulator cells in human autologous mixed lymphocyte cultures for generation of autorestricted CD8+ suppressor T cells. Immunol Lett. 1992 Feb 15; 31(3):233-6. PMID: 1347753; DOI: 10.1016/0165-2478(92)90119-9;

Balashov KE, Brondz BD. Different conditions for generation of non-cytotoxic autorestricted CD4-CD8+ human suppressor T cells and allospecific cytotoxic T lymphocytes in one-way mixed lymphocyte cultures: the role of adherent mononuclear cells. Scand J Immunol. 1991 Nov; 34(5):667-71. PMID: 1835128; DOI: 10.1111/j.1365-3083.1991.tb01590.x;

Balashov, K.E., Jandashevskaja, S.I., Pinegin, B.V. . Surface markers and functional activity of peripheral blood and synovial fluid lymphocytes in patients with juvenile rheumatoid arthritis. Immunologiia. 1991.
Demina, T.L., Boiko, A.N., Oganezov, V.K., Ketlinsky, S.A., Prokopiev, A.A., Balashov, K.E., Pinegin, B.V. Participation of tumor necrosis factor-alpha in immunoregulation of chronic progressive form of multiple sclerosis. Immunologiia. 1991.

Brondz BD, Balashov KE. The role of T lymphocytes in the immunotherapy of tumours. Biomed Sci. 1991; 2(5):441-9. PMID: 1840832

Karaulov AV, Balashov KE. [Cellular immunity in autoimmune diseases]. Ter Arkh. 1991; 63(4):147-50. PMID: 1676858

Puzin MN, Balashov KE. [The levels of the main classes of immunoglobulins in the serum and saliva of patients with trigeminal neuralgia]. Stomatologiia (Mosk). 1990 Mar-Apr; 69(2):49-50. PMID: 2371731

Grechko VE, Puzin MN, Balashov KE. [Immunologic status in autonomic prosopalgias]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1990; 90(1):54-7. PMID: 2158728

Demina TL, Boiko AN, Rossel's AN, Balashov KE, Popova NF. [Study of cellular immunity and the opioid peptide system in patients with multiple sclerosis]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1990; 90(2):19-24. PMID: 2160162

Balashov KE, Boiko AN, Glazko AV, Sidorenko IV, Shul'zhenko AE, Borisova AM, Karaulov AV. [Characteristics of the set-up of the lymphocyte blast transformation reaction using whole blood]. Lab Delo. 1990; (9):55-8. PMID: 1702865

Grechko VE, Puzin MN, Stepanchenko AV, Sineva NA, Kushlinskii NE, Balashov KE, Maksimovskii IuM, Bragin EO. [Diagnosis and treatment of neurostomatological diseases and syndromes]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1990; 90(9):103-5. PMID: 2176025

Puzin MN, Balashov KE, Kulakov AV, Ivaniushenkova IA. [Basic cellular indices of immunity in patients with various pain syndromes of the face and head]. Stomatologiia (Mosk). 1989 Nov-Dec; 68(6):28-9. PMID: 2623683

Demina TL, Boiko AN, Balashov KE, Pinegin BV. [Characteristics of cellular immunity in multiple sclerosis]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1989; 89(2):35-41. PMID: 2524943

Puzin MN, Kulakov AV, Balashov KE. [Immunologic aspects of migraine headaches and autonomic prosopalgias]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1989; 89(10):72-4. PMID: 2618237

Puzin MN, Kulakov AV, Balashov KE, Sharov MN, Vodop'ianov NP. [Local and general humoral immunity in patients with migraine, Horton's syndrome and autonomic pain]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1989; 89(2):56-8. PMID: 2728720

Puzin MN, Kulakov AV, Balashov KE, Sharov MN. [Immunological aspects of trigeminal neuralgia]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1989; 89(4):17-9. PMID: 2750373

Balashov KE, Letiagin VP, Ozherel'ev AS, Oleinikova OM, Kadagidze ZG. [Natural antitumor cytotoxicity of the whole blood of donors and cancer patients]. Vopr Onkol. 1987; 33(12):71-4. PMID: 3424710

Balashov KE, Tabagari DZ, Kadagidze ZG. [Isolation from the human peripheral blood of a fraction of mononuclear cells with high cytotoxicity against K-562 and HeLa target cells]. Eksp Onkol. 1987; 9(3):48-51. PMID: 3608904

Rytenko AN, Balashov KE, Sergeev AV. [Scanning electron microscopic method for studying the interaction of normal peritoneal macrophages with tumor cells]. Eksp Onkol. 1986; 8(6):52-7. PMID: 3100268

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 51 publications over 22 distinct years, with a maximum of 5 publications in 1989 and 1990 and 1991

Bar chart showing 51 publications over 22 distinct years, with a maximum of 5 publications in 1989 and 1990 and 1991

Year	Publications
1986	1
1987	2
1989	5
1990	5
1991	5
1992	1
1995	1
1997	2
1998	4
1999	1
2000	1
2004	1
2006	1
2010	4
2011	2
2012	4
2013	2
2014	2
2015	2
2016	3
2020	1
2022	1

2018 Rutgers Global International Travel Award

2015 National Multiple Sclerosis Society Pilot Research Award PP1506

2015 Rutgers-Robert Wood Johnson Medical School: Elected Fellow, Academy of Medical Educators, Institute for Excellence in Education

2013 Robert E. Leet and Clara Guthrie Patterson Trust Award in Clinical Research

2012 Elected Fellow, American Academy of Neurology

2011 RWJMS Dean’s Research Award for 2010 Best Publication in Clinical Sciences

2007 NIH Career Development Award 1K23NS052553

2007 National Multiple Sclerosis Society Research Award RG 3953A2/1

2005 National Multiple Sclerosis Society Pilot Research Award PP1153

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85 E. Concord St
Boston MA 02118
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