Keywords
Last Name

Katherine Semrau, PhD

TitleAssistant Professor
InstitutionBoston University School of Public Health
DepartmentGlobal Health
Address801 Massachusetts Ave Crosstown Center
Boston MA 02118
Phone(617) 414-1276
ORCID ORCID Icon0000-0002-8360-1391
Other Positions
TitleCenter Faculty Member
InstitutionBoston University School of Public Health
DepartmentCenter for Global Health & Development

 Research Expertise & Professional Interests
Katherine Semrau, PhD, MPH, has over 11 years of experience in the fields of HIV prevention, child mortality, and epidemiology. She is currently Assistant Professor of International Health and Director of the International Research Coordinating Center (IRCC). The IRCC provides study design, data management, and data analysis services for the Center for Global Health & Development at Boston University School of Public Health. Dr. Semrau’s research focuses on HIV-infected pregnant women, prevention of mother-to-child transmission, and prevention of child mortality. As the co-Principal Investigator of the Zambia Chlorhexidine Application Trial (ZamCAT), she leads the epidemiology and data analysis team for this cluster randomized control trial of 42,000 births in Southern Province, Zambia. As a team member of the Zambia Exclusive Breastfeeding Study, she lived in Zambia for over 3 years running the study laboratory and coordinating all enrollment, data collection and data management activities. She then returned to the U.S. and collaborated on multiple manuscripts from ZEBS and worked on qualitative projects examining HIV ARV access in Zambia and services for street children in the Republic of Georgia. Dr. Semrau’s dissertation research focused on breast problems, including mastitis and abscess, and HIV in HIV-infected women in Zambia. Her current interests include service delivery of PMTCT in Zambia and OVC care in Namibia/Ethiopia, prevention of child mortality, and clinical trials. Dr. Semrau has a PhD in epidemiology from Boston University and an MPH in international health and epidemiology from the University of Alabama-Birmingham.

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Nakamura KJ, Heath L, Sobrera ER, Wilkinson TA, Semrau K, Kankasa C, Tobin NH, Webb NE, Lee B, Thea DM, Kuhn L, Mullins JI, Aldrovandi GM. Breast milk and in utero transmission of HIV-1 select for envelope variants with unique molecular signatures. Retrovirology. 2017 Jan 26; 14(1):6. PMID: 28122636.
    View in: PubMed
  2. Semrau KE, Hirschhorn LR, Kodkany B, Spector JM, Tuller DE, King G, Lipsitz S, Sharma N, Singh VP, Kumar B, Dhingra-Kumar N, Firestone R, Kumar V, Gawande AA. Effectiveness of the WHO Safe Childbirth Checklist program in reducing severe maternal, fetal, and newborn harm in Uttar Pradesh, India: study protocol for a matched-pair, cluster-randomized controlled trial. Trials. 2016 Dec 07; 17(1):576. PMID: 27923401.
    View in: PubMed
  3. Semrau KE, Herlihy J, Grogan C, Musokotwane K, Yeboah-Antwi K, Mbewe R, Banda B, Mpamba C, Hamomba F, Pilingana P, Zulu A, Chanda-Kapata P, Biemba G, Thea DM, MacLeod WB, Simon JL, Hamer DH. Effectiveness of 4% chlorhexidine umbilical cord care on neonatal mortality in Southern Province, Zambia (ZamCAT): a cluster-randomised controlled trial. Lancet Glob Health. 2016 Nov; 4(11):e827-e836. PMID: 27693439.
    View in: PubMed
  4. Baqui AH, Mitra DK, Begum N, Hurt L, Soremekun S, Edmond K, Kirkwood B, Bhandari N, Taneja S, Mazumder S, Nisar MI, Jehan F, Ilyas M, Ali M, Ahmed I, Ariff S, Soofi SB, Sazawal S, Dhingra U, Dutta A, Ali SM, Ame SM, Semrau K, Hamomba FM, Grogan C, Hamer DH, Bahl R, Yoshida S, Manu A. Neonatal mortality within 24 hours of birth in six low- and lower-middle-income countries. Bull World Health Organ. 2016 Oct 01; 94(10):752-758B. PMID: 27843165.
    View in: PubMed
  5. Molina G, Weiser TG, Lipsitz SR, Esquivel MM, Uribe-Leitz T, Azad T, Shah N, Semrau K, Berry WR, Gawande AA, Haynes AB. Relationship Between Cesarean Delivery Rate and Maternal and Neonatal Mortality. JAMA. 2015 Dec 1; 314(21):2263-70. PMID: 26624825.
    View in: PubMed
  6. Herlihy JM, Hamomba L, Bonawitz R, Goggin CE, Sambambi K, Mwale J, Musonda V, Musokatwane K, Hopkins KL, Semrau K, Hammond EE, Duncan J, Knapp AB, Thea DM. Implementation and Operational Research: Integration of PMTCT and Antenatal Services Improves Combination Antiretroviral Therapy Uptake for HIV-Positive Pregnant Women in Southern Zambia: A Prototype for Option B+? J Acquir Immune Defic Syndr. 2015 Dec 1; 70(4):e123-9. PMID: 26181813.
    View in: PubMed
  7. Hurst TE, Semrau K, Patna M, Gawande A, Hirschhorn LR. Demand-side interventions for maternal care: evidence of more use, not better outcomes. BMC Pregnancy Childbirth. 2015; 15:297. PMID: 26566812.
    View in: PubMed
  8. Molina G, Esquivel MM, Uribe-Leitz T, Lipsitz SR, Azad T, Shah N, Semrau K, Berry WR, Gwande AA, Weiser TG, Haynes AB. Avoidable maternal and neonatal deaths associated with improving access to caesarean delivery in countries with low caesarean delivery rates: an ecological modelling analysis. Lancet. 2015 Apr 27; 385 Suppl 2:S33. PMID: 26313081.
    View in: PubMed
  9. Michalopoulos LT, Murray LK, Kane JC, Skavenski van Wyk S, Chomba E, Cohen J, Imasiku M, Semrau K, Unick J, Bolton PA. Testing the validity and reliability of the shame questionnaire among sexually abused girls in Zambia. PLoS One. 2015; 10(4):e0123820. PMID: 25879658.
    View in: PubMed
  10. Hamer DH, Herlihy JM, Musokotwane K, Banda B, Mpamba C, Mwangelwa B, Pilingana P, Thea DM, Simon JL, Yeboah-Antwi K, Grogan C, Semrau KE. Engagement of the community, traditional leaders, and public health system in the design and implementation of a large community-based, cluster-randomized trial of umbilical cord care in Zambia. Am J Trop Med Hyg. 2015 Mar; 92(3):666-72. PMID: 25646254.
    View in: PubMed
  11. Yeboah-Antwi K, Hamer DH, Semrau K, Waltensperger KZ, Snetro-Plewman G, Kambikambi C, Sakala A, Filumba S, Sichamba B, Marsh DR. Can a community health worker and a trained traditional birth attendant work as a team to deliver child health interventions in rural Zambia? BMC Health Serv Res. 2014; 14:516. PMID: 25344701.
    View in: PubMed
  12. Owens L, Semrau K, Mbewe R, Musokotwane K, Grogan C, Maine D, Hamer DH. The state of routine and emergency obstetric and neonatal care in Southern Province, Zambia. Int J Gynaecol Obstet. 2015 Jan; 128(1):53-7. PMID: 25441858.
    View in: PubMed
  13. Lunze K, Yeboah-Antwi K, Marsh DR, Kafwanda SN, Musso A, Semrau K, Waltensperger KZ, Hamer DH. Prevention and management of neonatal hypothermia in rural Zambia. PLoS One. 2014; 9(4):e92006. PMID: 24714630.
    View in: PubMed
  14. Herlihy JM, Shaikh A, Mazimba A, Gagne N, Grogan C, Mpamba C, Sooli B, Simamvwa G, Mabeta C, Shankoti P, Messersmith L, Semrau K, Hamer DH. Local perceptions, cultural beliefs and practices that shape umbilical cord care: a qualitative study in Southern Province, Zambia. PLoS One. 2013; 8(11):e79191. PMID: 24244447.
    View in: PubMed
  15. Brennan AT, Thea DM, Semrau K, Goggin C, Scott N, Pilingana P, Botha B, Mazimba A, Hamomba L, Seidenberg P. In-home HIV testing and nevirapine dosing by traditional birth attendants in rural Zambia: a feasibility study. J Midwifery Womens Health. 2014 Mar-Apr; 59(2):198-204. PMID: 24106818.
    View in: PubMed
  16. Semrau K, Kuhn L, Brooks DR, Cabral H, Sinkala M, Kankasa C, Thea DM, Aldrovandi GM. Dynamics of breast milk HIV-1 RNA with unilateral mastitis or abscess. J Acquir Immune Defic Syndr. 2013 Mar 1; 62(3):348-55. PMID: 23202812.
    View in: PubMed
  17. Messersmith LJ, Semrau K, Anh TL, Trang NN, Hoa DM, Eifler K, Sabin L. Women living with HIV in Vietnam: desire for children, use of sexual and reproductive health services, and advice from providers. Reprod Health Matters. 2012 Dec; 20(39 Suppl):27-38. PMID: 23177678.
    View in: PubMed
  18. Murray LK, Singh NS, Surkan PJ, Semrau K, Bass J, Bolton P. A qualitative study of georgian youth who are on the street or institutionalized. Int J Pediatr. 2012; 2012:921604. PMID: 23227056.
    View in: PubMed
  19. Vian T, Semrau K, Hamer DH, Loan le TT, Sabin LL. HIV/AIDS-Related Knowledge and Behaviors Among Most-at-Risk Populations in Vietnam. Open AIDS J. 2012; 6:259-65. PMID: 23173025.
    View in: PubMed
  20. Messersmith LJ, Semrau K, Hammett TM, Phong NT, Tung ND, Nguyen H, Glandon D, Huong NM, Anh HT. 'Many people know the law, but also many people violate it': discrimination experienced by people living with HIV/AIDS in Vietnam--results of a national study. Glob Public Health. 2013; 8 Suppl 1:S30-45. PMID: 22974225.
    View in: PubMed
  21. Seidenberg P, Nicholson S, Schaefer M, Semrau K, Bweupe M, Masese N, Bonawitz R, Chitembo L, Goggin C, Thea DM. Early infant diagnosis of HIV infection in Zambia through mobile phone texting of blood test results. Bull World Health Organ. 2012 May 1; 90(5):348-56. PMID: 22589568.
    View in: PubMed
  22. Hamer DH, Brooks ET, Semrau K, Pilingana P, MacLeod WB, Siazeele K, Sabin LL, Thea DM, Yeboah-Antwi K. Quality and safety of integrated community case management of malaria using rapid diagnostic tests and pneumonia by community health workers. Pathog Glob Health. 2012 Mar; 106(1):32-9. PMID: 22595272.
    View in: PubMed
  23. Murray LK, Bass J, Chomba E, Imasiku M, Thea D, Semrau K, Cohen JA, Lam C, Bolton P. Validation of the UCLA Child Post traumatic stress disorder-reaction index in Zambia. Int J Ment Health Syst. 2011; 5(1):24. PMID: 21943178.
    View in: PubMed
  24. Semrau K, Kuhn L, Brooks DR, Cabral H, Sinkala M, Kankasa C, Thea DM, Aldrovandi GM. Exclusive breastfeeding, maternal HIV disease, and the risk of clinical breast pathology in HIV-infected, breastfeeding women. Am J Obstet Gynecol. 2011 Oct; 205(4):344.e1-8. PMID: 21784403.
    View in: PubMed
  25. Hudacek DL, Kuruvilla S, Kim N, Semrau K, Thea D, Qazi S, Pleasant A, Shanahan J. Analyzing media coverage of the global fund diseases compared with lower funded diseases (childhood pneumonia, diarrhea and measles). PLoS One. 2011; 6(6):e20438. PMID: 21687711.
    View in: PubMed
  26. Yeboah-Antwi K, Pilingana P, Macleod WB, Semrau K, Siazeele K, Kalesha P, Hamainza B, Seidenberg P, Mazimba A, Sabin L, Kamholz K, Thea DM, Hamer DH. Community case management of fever due to malaria and pneumonia in children under five in Zambia: a cluster randomized controlled trial. PLoS Med. 2010 Sep; 7(9):e1000340. PMID: 20877714.
    View in: PubMed
  27. Chomba E, Murray L, Kautzman M, Haworth A, Kasese-Bota M, Kankasa C, Mwansa K, Amaya M, Thea D, Semrau K. Integration of services for victims of child sexual abuse at the university teaching hospital one-stop centre. J Trop Med. 2010; 2010. PMID: 20706671.
    View in: PubMed
  28. Heath L, Conway S, Jones L, Semrau K, Nakamura K, Walter J, Decker WD, Hong J, Chen T, Heil M, Sinkala M, Kankasa C, Thea DM, Kuhn L, Mullins JI, Aldrovandi GM. Restriction of HIV-1 genotypes in breast milk does not account for the population transmission genetic bottleneck that occurs following transmission. PLoS One. 2010; 5(4):e10213. PMID: 20422033.
    View in: PubMed
  29. Nakamura KJ, Gach JS, Jones L, Semrau K, Walter J, Bibollet-Ruche F, Decker JM, Heath L, Decker WD, Sinkala M, Kankasa C, Thea D, Mullins J, Kuhn L, Zwick MB, Aldrovandi GM. 4E10-resistant HIV-1 isolated from four subjects with rare membrane-proximal external region polymorphisms. PLoS One. 2010; 5(3):e9786. PMID: 20352106.
    View in: PubMed
  30. Kuhn L, Sinkala M, Semrau K, Kankasa C, Kasonde P, Mwiya M, Hu CC, Tsai WY, Thea DM, Aldrovandi GM. Elevations in mortality associated with weaning persist into the second year of life among uninfected children born to HIV-infected mothers. Clin Infect Dis. 2010 Feb 1; 50(3):437-44. PMID: 20047479.
    View in: PubMed
  31. Walter J, Ghosh MK, Kuhn L, Semrau K, Sinkala M, Kankasa C, Thea DM, Aldrovandi GM. High concentrations of interleukin 15 in breast milk are associated with protection against postnatal HIV transmission. J Infect Dis. 2009 Nov 15; 200(10):1498-502. PMID: 19835475.
    View in: PubMed
  32. Kuhn L, Semrau K, Ramachandran S, Sinkala M, Scott N, Kasonde P, Mwiya M, Kankasa C, Decker D, Thea DM, Aldrovandi GM. Mortality and virologic outcomes after access to antiretroviral therapy among a cohort of HIV-infected women who received single-dose nevirapine in Lusaka, Zambia. J Acquir Immune Defic Syndr. 2009 Sep 1; 52(1):132-6. PMID: 19506483.
    View in: PubMed
  33. Walter J, Kuhn L, Semrau K, Decker DW, Sinkala M, Kankasa C, Thea DM, Bulterys M, Ou CY, Aldrovandi GM. Detection of low levels of human immunodeficiency virus (HIV) may be critical for early diagnosis of pediatric HIV infection by use of dried blood spots. J Clin Microbiol. 2009 Sep; 47(9):2989-91. PMID: 19625479.
    View in: PubMed
  34. Kuhn L, Aldrovandi GM, Sinkala M, Kankasa C, Semrau K, Kasonde P, Mwiya M, Tsai WY, Thea DM. Differential effects of early weaning for HIV-free survival of children born to HIV-infected mothers by severity of maternal disease. PLoS One. 2009; 4(6):e6059. PMID: 19557167.
    View in: PubMed
  35. Murray LK, Semrau K, McCurley E, Thea DM, Scott N, Mwiya M, Kankasa C, Bass J, Bolton P. Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women: a qualitative study. AIDS Care. 2009 Jan; 21(1):78-86. PMID: 19085223.
    View in: PubMed
  36. Walter J, Kuhn L, Kankasa C, Semrau K, Sinkala M, Thea DM, Aldrovandi GM. Reuse of single-dose nevirapine in subsequent pregnancies for the prevention of mother-to-child HIV transmission in Lusaka, Zambia: a cohort study. BMC Infect Dis. 2008; 8:172. PMID: 19116004.
    View in: PubMed
  37. Kuhn L, Aldrovandi GM, Sinkala M, Kankasa C, Semrau K, Mwiya M, Kasonde P, Scott N, Vwalika C, Walter J, Bulterys M, Tsai WY, Thea DM. Effects of early, abrupt weaning on HIV-free survival of children in Zambia. N Engl J Med. 2008 Jul 10; 359(2):130-41. PMID: 18525036.
    View in: PubMed
  38. Semrau K, Ghosh M, Kankasa C, Sinkala M, Kasonde P, Mwiya M, Thea DM, Kuhn L, Aldrovandi GM. Temporal and lateral dynamics of HIV shedding and elevated sodium in breast milk among HIV-positive mothers during the first 4 months of breast-feeding. J Acquir Immune Defic Syndr. 2008 Mar 1; 47(3):320-8. PMID: 18398972.
    View in: PubMed
  39. Kuhn L, Sinkala M, Kankasa C, Semrau K, Kasonde P, Scott N, Mwiya M, Vwalika C, Walter J, Tsai WY, Aldrovandi GM, Thea DM. High uptake of exclusive breastfeeding and reduced early post-natal HIV transmission. PLoS One. 2007; 2(12):e1363. PMID: 18159246.
    View in: PubMed
  40. Walter J, Kuhn L, Ghosh MK, Kankasa C, Semrau K, Sinkala M, Mwiya M, Thea DM, Aldrovandi GM. Low and undetectable breast milk interleukin-7 concentrations are associated with reduced risk of postnatal HIV transmission. J Acquir Immune Defic Syndr. 2007 Oct 1; 46(2):200-7. PMID: 17667336.
    View in: PubMed
  41. Dorosko SM, Thea DM, Saperstein G, Russell RM, Paape MJ, Hinckley LS, Decker WD, Semrau K, Sinkala M, Kasonde P, Kankasa C, Aldrovandi GM, Hamer DH. Veterinary field test as screening tool for mastitis and HIV-1 viral load in breastmilk from HIV-infected Zambian women. Breastfeed Med. 2007 Sep; 2(3):172-5. PMID: 17903106.
    View in: PubMed
  42. Murray LK, Haworth A, Semrau K, Singh M, Aldrovandi GM, Sinkala M, Thea DM, Bolton PA. Violence and abuse among HIV-infected women and their children in Zambia: a qualitative study. J Nerv Ment Dis. 2006 Aug; 194(8):610-5. PMID: 16909070.
    View in: PubMed
  43. Thea DM, Aldrovandi G, Kankasa C, Kasonde P, Decker WD, Semrau K, Sinkala M, Kuhn L. Post-weaning breast milk HIV-1 viral load, blood prolactin levels and breast milk volume. AIDS. 2006 Jul 13; 20(11):1539-47. PMID: 16847409.
    View in: PubMed
  44. Semrau K, Kuhn L, Kasonde P, Sinkala M, Kankasa C, Shutes E, Vwalika C, Ghosh M, Aldrovandi G, Thea DM. Impact of chloroquine on viral load in breast milk. Trop Med Int Health. 2006 Jun; 11(6):800-3. PMID: 16772000.
    View in: PubMed
  45. Albrecht S, Semrau K, Kasonde P, Sinkala M, Kankasa C, Vwalika C, Aldrovandi GM, Thea DM, Kuhn L. Predictors of nonadherence to single-dose nevirapine therapy for the prevention of mother-to-child HIV transmission. J Acquir Immune Defic Syndr. 2006 Jan 1; 41(1):114-8. PMID: 16340483.
    View in: PubMed
  46. Kuhn L, Kasonde P, Sinkala M, Kankasa C, Semrau K, Scott N, Tsai WY, Vermund SH, Aldrovandi GM, Thea DM. Does severity of HIV disease in HIV-infected mothers affect mortality and morbidity among their uninfected infants? Clin Infect Dis. 2005 Dec 1; 41(11):1654-61. PMID: 16267740.
    View in: PubMed
  47. Kuhn L, Kasonde P, Sinkala M, Kankasa C, Semrau K, Vwalika C, Tsai WY, Aldrovandi GM, Thea DM. Prolonged breast-feeding and mortality up to two years post-partum among HIV-positive women in Zambia. AIDS. 2005 Oct 14; 19(15):1677-81. PMID: 16184038.
    View in: PubMed
  48. Kuhn L, Trabattoni D, Kankasa C, Semrau K, Kasonde P, Lissoni F, Sinkala M, Ghosh M, Vwalika C, Aldrovandi GM, Thea DM, Clerici M. Alpha-defensins in the prevention of HIV transmission among breastfed infants. J Acquir Immune Defic Syndr. 2005 Jun 1; 39(2):138-42. PMID: 15905728.
    View in: PubMed
  49. Semrau K, Kuhn L, Vwalika C, Kasonde P, Sinkala M, Kankasa C, Shutes E, Aldrovandi G, Thea DM. Women in couples antenatal HIV counseling and testing are not more likely to report adverse social events. AIDS. 2005 Mar 24; 19(6):603-9. PMID: 15802979.
    View in: PubMed
  50. Thea DM, Vwalika C, Kasonde P, Kankasa C, Sinkala M, Semrau K, Shutes E, Ayash C, Tsai WY, Aldrovandi G, Kuhn L. Issues in the design of a clinical trial with a behavioral intervention--the Zambia exclusive breast-feeding study. Control Clin Trials. 2004 Aug; 25(4):353-65. PMID: 15296810.
    View in: PubMed
  51. Ghosh MK, Kuhn L, West J, Semrau K, Decker D, Thea DM, Aldrovandi GM. Quantitation of human immunodeficiency virus type 1 in breast milk. J Clin Microbiol. 2003 Jun; 41(6):2465-70. PMID: 12791866.
    View in: PubMed
  52. Sabbaj S, Edwards BH, Ghosh MK, Semrau K, Cheelo S, Thea DM, Kuhn L, Ritter GD, Mulligan MJ, Goepfert PA, Aldrovandi GM. Human immunodeficiency virus-specific CD8(+) T cells in human breast milk. J Virol. 2002 Aug; 76(15):7365-73. PMID: 12097549.
    View in: PubMed
Katherine's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
BU Co-Authors
_
Similar BU People
_
Same Department