Christopher Connor | Profiles RNS

Christopher Connor, MD, PhD

Adjunct Associate Professor

Boston University Chobanian & Avedisian School of Medicine

Pharmacology, Physiology & Biophysics

MD, Harvard Medical School
PhD, Massachusetts Institute of Technology
MA, Trinity College, Cambridge
BA, Trinity College, Cambridge

Websites

	Brigham and Womens Profile
	LinkedIn

Applying the principles of minimally-invasive medical engineering, physiology and information technology to clinical issues in anesthesiology.

Computerized assessment of patient facial appearance to predict the ease or difficulty of endotracheal intubation at surgery.

Improving the delivery of intravenous anesthetic agents through improved, interactive modeling of their pharmacokinetics and pharmacodynamics.

Simulating free-swimming ascent from disabled submarines at depths greater than 600 feet, and improving the survivability of rapid compression and exposure to high pressure oxygen and nitrogen.

Intelligent alarm systems for intra-operative patient monitoring.

BU Research
NIH RePORTER Research

Pan-neuronal functional imaging and anesthesia
09/01/2022 - 08/31/2027 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIGMS
1R35GM145319-01

Pan-neuronal functional imaging and anesthesia in C.elegans
09/15/2017 - 08/31/2023 (PI)
NIH/National Institute of General Medical Sciences
5R01GM121457-05

Pan-neuronal imaging of nociceptive pain, neuropathic pain and opioid effects in C. elegans
12/01/2021 - 11/30/2022 (Subcontract PI)
The Brigham and Women's Hospital, Inc. McGraw Foundation

Pan-neuronal imaging of nociceptive pain, neuropathic pain and opioid effects in C. elegans (Billing Agreement for Andrew Chang)
12/01/2021 - 11/30/2022 (Subcontract PI)
The Brigham and Women's Hospital, Inc. McGraw Foundation

Title

Yr	Title	Project-Sub Proj	Pubs
2023	Pan-neuronal functional imaging and anesthesia	5R35GM145319-02
2022	Pan-neuronal functional imaging and anesthesia	1R35GM145319-01
2021	Pan-neuronal functional imaging and anesthesia	5R01GM121457-05	4
2020	Pan-neuronal functional imaging and anesthesia	5R01GM121457-04	4
2019	Pan-neuronal functional imaging and anesthesia	5R01GM121457-03	4
2018	Pan-neuronal functional imaging and anesthesia	3R01GM121457-02S1	4
2018	Pan-neuronal functional imaging and anesthesia	5R01GM121457-02	4
2017	Pan-neuronal functional imaging and anesthesia	1R01GM121457-01A1	4

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Lanza E, Lucente V, Nicoletti M, Schwartz S, Cavallo IF, Caprini D, Connor CW, Saifuddin MFA, Miller JM, L'Etoile ND, Folli V. See Elegans: Simple-to-use, accurate, and automatic 3D detection of neural activity from densely packed neurons. PLoS One. 2024; 19(3):e0300628. PMID: 38517838; PMCID: PMC10959381; DOI: 10.1371/journal.pone.0300628;

Connor CW. Understanding New Machine Learning Architectures: Practical Generative Artificial Intelligence for Anesthesiologists. Anesthesiology. 2024 Mar 01; 140(3):599-609. PMID: 38349761; PMCID: PMC10868863; DOI: 10.1097/ALN.0000000000004841;

Chang AS, Wirak GS, Li D, Gabel CV, Connor CW. Measures of Information Content during Anesthesia and Emergence in the Caenorhabditis elegans Nervous System. Anesthesiology. 2023 Jul 01; 139(1):49-62.View Related Profiles.

Connor, Christopher
Gabel, Christopher
Wirak, Gregory

PMID: 37027802; PMCID: PMC10266588; DOI: 10.1097/ALN.0000000000004579;

Gerner P, Connor CW, Stone AB. Visual assessment of effectiveness of ultrasound probe hygiene using ultraviolet fluorescent powder: a pilot study. Reg Anesth Pain Med. 2023 Jun 01. PMID: 37263744; PMCID: PMC10689569; DOI: 10.1136/rapm-2023-104632;

Connor CW. In Response. Anesth Analg. 2023 Jun 01; 136(6):e35-e36. PMID: 37205819; PMCID: PMC10434827; DOI: 10.1213/ANE.0000000000006434;

Connor CW. In Response. Anesth Analg. 2023 May 01; 136(5):e22-e24. PMID: 37058739; PMCID: PMC10187762; DOI: 10.1213/ANE.0000000000006431;

Connor CW. Open Reimplementation of the BIS Algorithms for Depth of Anesthesia. Anesth Analg. 2022 10 01; 135(4):855-864. PMID: 35767469; PMCID: PMC9481655; DOI: 10.1213/ANE.0000000000006119;

Wirak GS, Florman J, Alkema MJ, Connor CW, Gabel CV. Age-associated changes to neuronal dynamics involve a disruption of excitatory/inhibitory balance in C. elegans. Elife. 2022 Jun 15; 11.View Related Profiles.

Connor, Christopher
Gabel, Christopher
Wirak, Gregory

PMID: 35703498; PMCID: PMC9273219; DOI: 10.7554/eLife.72135;

Owens GE, Connor CW. Controlling Anesthesia Hardware With Simple Hand Gestures: Thumbs Up or Thumbs Down? Anesth Analg. 2021 07 01; 133(1):243-250. PMID: 32701544; PMCID: PMC7855226; DOI: 10.1213/ANE.0000000000005071;

Connor CW. Emulation of the BIS engine. J Clin Monit Comput. 2022 Apr; 36(2):483-492. PMID: 33742345; PMCID: PMC8449791; DOI: 10.1007/s10877-021-00676-2;

Showing 10 of 41 results. Show More

Connor CW. A Forensic Disassembly of the BIS Monitor. Anesth Analg. 2020 12; 131(6):1923-1933. PMID: 33093360; PMCID: PMC7669712; DOI: 10.1213/ANE.0000000000005220;

Wirak GS, Gabel CV, Connor CW. Isoflurane Exposure in Juvenile Caenorhabditis elegans Causes Persistent Changes in Neuron Dynamics. Anesthesiology. 2020 09; 133(3):569-582.View Related Profiles.

Connor, Christopher
Gabel, Christopher
Wirak, Gregory

PMID: 32452864; PMCID: PMC7429306; DOI: 10.1097/ALN.0000000000003335;

Connor CW, Palmer LJ, Pentakota S. Remote Control and Monitoring of GE Aisys Anesthesia Machines Repurposed as Intensive Care Unit Ventilators. Anesthesiology. 2020 08; 133(2):477-479. PMID: 32358251; PMCID: PMC7223577; DOI: 10.1097/ALN.0000000000003371;

Awal MR, Wirak GS, Gabel CV, Connor CW. Collapse of Global Neuronal States in Caenorhabditis elegans under Isoflurane Anesthesia. Anesthesiology. 2020 07; 133(1):133-144.View Related Profiles.

Connor, Christopher
Gabel, Christopher
Wirak, Gregory
Awal, Mehraj

PMID: 32282426; PMCID: PMC7577177; DOI: 10.1097/ALN.0000000000003304;

Canelli R, Connor CW, Gonzalez M, Nozari A, Ortega R. Barrier Enclosure during Endotracheal Intubation. N Engl J Med. 2020 05 14; 382(20):1957-1958.View Related Profiles.

Nozari, Ala
Connor, Christopher
Gonzalez, Mauricio
Ortega, Rafael
Canelli, Robert

PMID: 32243118; PMCID: PMC7151333; DOI: 10.1056/NEJMc2007589;

Connor CW. Artificial Intelligence and Machine Learning in Anesthesiology. Anesthesiology. 2019 12; 131(6):1346-1359. PMID: 30973516; PMCID: PMC6778496; DOI: 10.1097/ALN.0000000000002694;

Awal MR, Austin D, Florman J, Alkema M, Gabel CV, Connor CW. Breakdown of Neural Function under Isoflurane Anesthesia: In Vivo, Multineuronal Imaging in Caenorhabditis elegans. Anesthesiology. 2018 10; 129(4):733-743.View Related Profiles.

Connor, Christopher
Gabel, Christopher
Awal, Mehraj

PMID: 30004907; PMCID: PMC6148381; DOI: 10.1097/ALN.0000000000002342;

Harrison MJ, Connor CW, Cumin D. Pediatric blood pressures during anesthesia assessed using normalization and principal component analysis techniques. J Clin Monit Comput. 2019 Aug; 33(4):589-595. PMID: 30267373; PMCID: PMC6438775; DOI: 10.1007/s10877-018-0199-z;

Connor CW. Optimizing target control of the vessel rich group with volatile anesthetics. J Clin Monit Comput. 2019 Jun; 33(3):445-454. PMID: 29931573; PMCID: PMC6309525; DOI: 10.1007/s10877-018-0169-5;

Connor C, Deng W, Ortega R. Use of Pressure Transducers. N Engl J Med. 2017 07 27; 377(4):401.View Related Profiles.

Connor, Christopher
Ortega, Rafael

PMID: 28745991

Ortega R, Connor C, Kotova F, Deng W, Lacerra C. Use of Pressure Transducers. N Engl J Med. 2017 Apr 06; 376(14):e26.View Related Profiles.

Connor, Christopher
Ortega, Rafael

PMID: 28379806; DOI: 10.1056/NEJMvcm1513613;

Connor CW, Herzig M. Monitoring the Location of Staff via Mobile Devices in a Large Multifacility Practice Group. A A Case Rep. 2016 May 15; 6(10):320-8. PMID: 26867022; DOI: 10.1213/XAA.0000000000000288;

Saffary R, Feliz E, Connor CW. Cricoid cartilage compression devices. Anaesthesia. 2015 Apr; 70(4):504. PMID: 25764410; DOI: 10.1111/anae.13056;

Ortega R, Connor C, Rodriguez G. Endotracheal extubation. N Engl J Med. 2014 Mar 27; 370(13):1267-8.View Related Profiles.

Connor, Christopher
Rodriguez, Gerardo
Ortega, Rafael

PMID: 24670181; DOI: 10.1056/NEJMc1401725;

Connor CW, Gonzalez RM. Images in anesthesiology: the preoperative stop/go sign. Anesthesiology. 2014 Mar; 120(3):751.View Related Profiles.

Connor, Christopher
Gonzalez, Mauricio

PMID: 23388192; DOI: 10.1097/ALN.0b013e3182887547;

Connor CW, Segal S. The importance of subjective facial appearance on the ability of anesthesiologists to predict difficult intubation. Anesth Analg. 2014 Feb; 118(2):419-27. PMID: 24361845; DOI: 10.1213/ANE.0000000000000012;

Chima RS, Ortega R, Connor CW. Melodic algorithms for pulse oximetry to allow audible discrimination of abnormal systolic blood pressures. J Clin Monit Comput. 2014 Dec; 28(6):597-603.View Related Profiles.

Connor, Christopher
Ortega, Rafael

PMID: 24474369; DOI: 10.1007/s10877-014-9558-6;

Ortega R, Connor C, Rodriguez G, Spencer C. Videos in clinical medicine. Endotracheal extubation. N Engl J Med. 2014 Jan 16; 370(3):e4.View Related Profiles.

Connor, Christopher
Rodriguez, Gerardo
Ortega, Rafael

PMID: 24428490; DOI: 10.1056/NEJMvcm1300964;

Connor CW, Saffary R, Feliz E. Performance of the Sellick maneuver significantly improves when residents and trained nurses use a visually interactive guidance device in simulation. Physiol Meas. 2013 Dec; 34(12):1645-56. PMID: 24201217; DOI: 10.1088/0967-3334/34/12/1645;

Ortega R, Connor C, Kim S, Djang R, Patel K. Monitoring ventilation with capnography. N Engl J Med. 2012 Nov 8; 367(19):e27.View Related Profiles.

Connor, Christopher
Ortega, Rafael

PMID: 23134404; DOI: 10.1056/NEJMvcm1105237;

Ferrigno M, Tahir N, Connor CW. The feasibility of pharmacological mitigation of nitrogen narcosis during submarine escapes from depths down to 1,000 fsw. Undersea Hyperb Med. 2011 Nov-Dec; 38(6):549-55. PMID: 22292260

Connor CW, Segal S. Accurate classification of difficult intubation by computerized facial analysis. Anesth Analg. 2011 Jan; 112(1):84-93. PMID: 21081769; DOI: 10.1213/ANE.0b013e31820098d6;

Connor CW, Ferrigno M. Estimates of N2 narcosis and O2 toxicity during submarine escapes from 600 to 1,000 fsw. Undersea Hyperb Med. 2009 Jul-Aug; 36(4):237-45. PMID: 20088242

Connor CW, Gohil B, Harrison MJ. Triggering of systolic arterial pressure alarms using statistics-based versus threshold alarms. Anaesthesia. 2009 Feb; 64(2):131-5. PMID: 19143688; DOI: 10.1111/j.1365-2044.2008.05738.x;

Connor CW, Philip JH. Closed-form solutions for the optimum equivalence of first-order compartmental models and their implications for classical models of closed-circuit anesthesia. Physiol Meas. 2009 Feb; 30(2):N11-21. PMID: 19136733; DOI: 10.1088/0967-3334/30/2/N01;

Connor CW, Philip JH. The Severinghaus square root of time relationship for anesthetic uptake and its implications for the stability of compartmental pharmacokinetics. Physiol Meas. 2008 May; 29(5):685-701. PMID: 18460768; DOI: 10.1088/0967-3334/29/5/012;

Harrison MJ, Connor CW. Statistics-based alarms from sequential physiological measurements. Anaesthesia. 2007 Oct; 62(10):1015-23. PMID: 17845653; DOI: 10.1111/j.1365-2044.2007.05187.x;

Connor CW, Hynynen K. Patterns of thermal deposition in the skull during transcranial focused ultrasound surgery. IEEE Trans Biomed Eng. 2004 Oct; 51(10):1693-706. PMID: 15490817

Connor CW, Clement GT, Hynynen K. A unified model for the speed of sound in cranial bone based on genetic algorithm optimization. Phys Med Biol. 2002 Nov 21; 47(22):3925-44. PMID: 12476974

Connor CW, Hynynen K. Bio-acoustic thermal lensing and nonlinear propagation in focused ultrasound surgery using large focal spots: a parametric study. Phys Med Biol. 2002 Jun 7; 47(11):1911-28. PMID: 12108775

Rawat N, Connor CW, Jones JA, Kozlovskaya IB, Sullivan P. The correlation between aerobic fitness and motion sickness susceptibility. Aviat Space Environ Med. 2002 Mar; 73(3):216-8. PMID: 11908888

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 41 publications over 20 distinct years, with a maximum of 5 publications in 2014 and 2020

Bar chart showing 41 publications over 20 distinct years, with a maximum of 5 publications in 2014 and 2020

Year	Publications
2002	3
2004	1
2007	1
2008	1
2009	3
2010	1
2011	1
2012	1
2013	1
2014	5
2015	1
2016	1
2017	2
2018	3
2019	1
2020	5
2021	2
2022	2
2023	4
2024	2

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