Keywords
Last Name

Brygida Berse, PhD

TitleAdjunct Research Assistant Professor
InstitutionBoston University School of Medicine
DepartmentPathology & Laboratory Medicine
DivisionOther Pathology
Address200 Springs Rd
Bedford MA 01730
Phone(617) 638-4500
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

InstitutionBedford VA - Edith Nourse Rogers Memorial VA Hosp

 Research Expertise & Professional Interests
Field of study: Molecular Biology/Neuroscience
Expertise: gene expression; signal transduction; cholinergic biology.

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Chun DS, Berse B, Venne VL, DuVall SL, Filipski KK, Kelley MJ, Meyer LJ, Icardi MS, Lynch JA. BRCA testing within the Department of Veterans Affairs: concordance with clinical practice guidelines. Fam Cancer. 2017 Jan; 16(1):41-49. PMID: 27589855.
    View in: PubMed
  2. Lynch JA, Berse B, Chun D, Rivera D, Filipski KK, Kulich S, Viernes B, DuVall SL, Kelley MJ. Epidermal Growth Factor Receptor Mutational Testing and Erlotinib Treatment Among Veterans Diagnosed With Lung Cancer in the United States Department of Veterans Affairs. Clin Lung Cancer. 2016 Dec 07. PMID: 28038980.
    View in: PubMed
  3. Lynch J, DuVall SL, Berse B, Whatley A, St Pierre C, Oloruntoba O, Hunt CM. Implementation of Pharmacogenetic Testing Within the Veterans Health Administration From 2011 to 2013. Mil Med. 2016 Oct; 181(10):1375-1381. PMID: 27753578.
    View in: PubMed
  4. Lynch J, Berse B. Methods to identify BRCA testing in claims data. Am J Obstet Gynecol. 2016 Jul; 215(1):133-4. PMID: 27083760.
    View in: PubMed
  5. Lynch JA, Berse B, Petkov V, Filipski K, Zhou Y, Khoury MJ, Hassett M, Freedman AN. Implementation of the 21-gene recurrence score test in the United States in 2011. Genet Med. 2016 Oct; 18(10):982-90. PMID: 26890451.
    View in: PubMed
  6. Lynch JA, Venne V, Berse B. Genetic tests to identify risk for breast cancer. Semin Oncol Nurs. 2015 May; 31(2):100-7. PMID: 25951739.
    View in: PubMed
  7. Berse B, Lynch JA. Molecular diagnostic testing in breast cancer. Semin Oncol Nurs. 2015 May; 31(2):108-21. PMID: 25951740.
    View in: PubMed
  8. Madziar B, Shah S, Brock M, Burke R, Lopez-Coviella I, Nickel AC, Cakal EB, Blusztajn JK, Berse B. Nerve growth factor regulates the expression of the cholinergic locus and the high-affinity choline transporter via the Akt/PKB signaling pathway. J Neurochem. 2008 Dec; 107(5):1284-93. PMID: 18793330.
    View in: PubMed
  9. Brock M, Nickel AC, Madziar B, Blusztajn JK, Berse B. Differential regulation of the high affinity choline transporter and the cholinergic locus by cAMP signaling pathways. Brain Res. 2007 May 11; 1145:1-10. PMID: 17320829.
    View in: PubMed
  10. Lopez-Coviella I, Mellott TM, Kovacheva VP, Berse B, Slack BE, Zemelko V, Schnitzler A, Blusztajn JK. Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrain. Brain Res. 2006 May 9; 1088(1):49-56. PMID: 16626664.
    View in: PubMed
  11. Berse B, Szczecinska W, Lopez-Coviella I, Madziar B, Zemelko V, Kaminski R, Kozar K, Lips KS, Pfeil U, Blusztajn JK. Expression of high affinity choline transporter during mouse development in vivo and its upregulation by NGF and BMP-4 in vitro. Brain Res Dev Brain Res. 2005 Jun 30; 157(2):132-40. PMID: 15885806.
    View in: PubMed
  12. Lopez-Coviella I, Follettie MT, Mellott TJ, Kovacheva VP, Slack BE, Diesl V, Berse B, Thies RS, Blusztajn JK. Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6984-9. PMID: 15870197.
    View in: PubMed
  13. Madziar B, Lopez-Coviella I, Zemelko V, Berse B. Regulation of cholinergic gene expression by nerve growth factor depends on the phosphatidylinositol-3'-kinase pathway. J Neurochem. 2005 Feb; 92(4):767-79. PMID: 15686478.
    View in: PubMed
  14. Burau K, Stenull I, Huber K, Misawa H, Berse B, Unsicker K, Ernsberger U. c-ret regulates cholinergic properties in mouse sympathetic neurons: evidence from mutant mice. Eur J Neurosci. 2004 Jul; 20(2):353-62. PMID: 15233745.
    View in: PubMed
  15. Brandon EP, Mellott T, Pizzo DP, Coufal N, D'Amour KA, Gobeske K, Lortie M, López-Coviella I, Berse B, Thal LJ, Gage FH, Blusztajn JK. Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency. J Neurosci. 2004 Jun 16; 24(24):5459-66. PMID: 15201317.
    View in: PubMed
  16. Mellott T, Lopez-Coviella I, Blusztajn JK, Berse B. Mitogen-activated protein kinase kinase negatively modulates ciliary neurotrophic factor-activated choline acetyltransferase gene expression. Eur J Biochem. 2002 Feb; 269(3):850-8. PMID: 11846786.
    View in: PubMed
  17. López-Coviella I, Berse B, Thies RS, Blusztajn JK. Upregulation of acetylcholine synthesis by bone morphogenetic protein 9 in a murine septal cell line. J Physiol Paris. 2002 Jan-Mar; 96(1-2):53-9. PMID: 11755783.
    View in: PubMed
  18. Malik MA, Greenwood CE, Blusztajn JK, Berse B. Cholinergic differentiation triggered by blocking cell proliferation and treatment with all-trans-retinoic acid. Brain Res. 2000 Aug 25; 874(2):178-85. PMID: 10960602.
    View in: PubMed
  19. López-Coviella I, Berse B, Krauss R, Thies RS, Blusztajn JK. Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9. Science. 2000 Jul 14; 289(5477):313-6. PMID: 10894782.
    View in: PubMed
  20. Fiucci G, Czarny M, Lavie Y, Zhao D, Berse B, Blusztajn JK, Liscovitch M. Changes in phospholipase D isoform activity and expression in multidrug-resistant human cancer cells. Int J Cancer. 2000 Mar 15; 85(6):882-8. PMID: 10709112.
    View in: PubMed
  21. Blusztajn JK, Berse B. The cholinergic neuronal phenotype in Alzheimer's disease. Metab Brain Dis. 2000 Mar; 15(1):45-64. PMID: 10885540.
    View in: PubMed
  22. Berse B, Lopez-Coviella I, Blusztajn JK. Activation of TrkA by nerve growth factor upregulates expression of the cholinergic gene locus but attenuates the response to ciliary neurotrophic growth factor. Biochem J. 1999 Sep 1; 342 ( Pt 2):301-8. PMID: 10455015.
    View in: PubMed
  23. Berse B, Hunt JA, Diegel RJ, Morganelli P, Yeo K, Brown F, Fava RA. Hypoxia augments cytokine (transforming growth factor-beta (TGF-beta) and IL-1)-induced vascular endothelial growth factor secretion by human synovial fibroblasts. Clin Exp Immunol. 1999 Jan; 115(1):176-82. PMID: 9933439.
    View in: PubMed
  24. Zhao D, Berse B, Holler T, Cermak JM, Blusztajn JK. Developmental changes in phospholipase D activity and mRNA levels in rat brain. Brain Res Dev Brain Res. 1998 Aug 8; 109(2):121-7. PMID: 9729325.
    View in: PubMed
  25. Berse B, Blusztajn JK. Modulation of cholinergic locus expression by glucocorticoids and retinoic acid is cell-type specific. FEBS Lett. 1997 Jun 30; 410(2-3):175-9. PMID: 9237624.
    View in: PubMed
  26. Detmar M, Brown LF, Berse B, Jackman RW, Elicker BM, Dvorak HF, Claffey KP. Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin. J Invest Dermatol. 1997 Mar; 108(3):263-8. PMID: 9036922.
    View in: PubMed
  27. Holler T, Berse B, Cermak JM, Diebler MF, Blusztajn JK. Differences in the developmental expression of the vesicular acetylcholine transporter and choline acetyltransferase in the rat brain. Neurosci Lett. 1996 Jul 12; 212(2):107-10. PMID: 8832650.
    View in: PubMed
  28. Wasowska B, Wieder KJ, Hancock WW, Zheng XX, Berse B, Binder J, Strom TB, Kupiec-Weglinski JW. Cytokine and alloantibody networks in long term cardiac allografts in rat recipients treated with rapamycin. J Immunol. 1996 Jan 1; 156(1):395-404. PMID: 8598490.
    View in: PubMed
  29. Dubin D, Peters JH, Brown LF, Logan B, Kent KC, Berse B, Berven S, Cercek B, Sharifi BG, Pratt RE, et al. Balloon catheterization induced arterial expression of embryonic fibronectins. Arterioscler Thromb Vasc Biol. 1995 Nov; 15(11):1958-67. PMID: 7583577.
    View in: PubMed
  30. Berse B, Blusztajn JK. Coordinated up-regulation of choline acetyltransferase and vesicular acetylcholine transporter gene expression by the retinoic acid receptor alpha, cAMP, and leukemia inhibitory factor/ciliary neurotrophic factor signaling pathways in a murine septal cell line. J Biol Chem. 1995 Sep 22; 270(38):22101-4. PMID: 7673184.
    View in: PubMed
  31. Guidi AJ, Abu-Jawdeh G, Berse B, Jackman RW, Tognazzi K, Dvorak HF, Brown LF. Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia. J Natl Cancer Inst. 1995 Aug 16; 87(16):1237-45. PMID: 7563170.
    View in: PubMed
  32. Brown LF, Yeo KT, Berse B, Morgentaler A, Dvorak HF, Rosen S. Vascular permeability factor (vascular endothelial growth factor) is strongly expressed in the normal male genital tract and is present in substantial quantities in semen. J Urol. 1995 Aug; 154(2 Pt 1):576-9. PMID: 7609140.
    View in: PubMed
  33. Pedersen WA, Berse B, Schüler U, Wainer BH, Blusztajn JK. All-trans- and 9-cis-retinoic acid enhance the cholinergic properties of a murine septal cell line: evidence that the effects are mediated by activation of retinoic acid receptor-alpha. J Neurochem. 1995 Jul; 65(1):50-8. PMID: 7790895.
    View in: PubMed
  34. Detmar M, Yeo KT, Nagy JA, Van de Water L, Brown LF, Berse B, Elicker BM, Ledbetter S, Dvorak HF. Keratinocyte-derived vascular permeability factor (vascular endothelial growth factor) is a potent mitogen for dermal microvascular endothelial cells. J Invest Dermatol. 1995 Jul; 105(1):44-50. PMID: 7615975.
    View in: PubMed
  35. Brown LF, Harrist TJ, Yeo KT, Ståhle-Bäckdahl M, Jackman RW, Berse B, Tognazzi K, Dvorak HF, Detmar M. Increased expression of vascular permeability factor (vascular endothelial growth factor) in bullous pemphigoid, dermatitis herpetiformis, and erythema multiforme. J Invest Dermatol. 1995 May; 104(5):744-9. PMID: 7738351.
    View in: PubMed
  36. Brown LF, Olbricht SM, Berse B, Jackman RW, Matsueda G, Tognazzi KA, Manseau EJ, Dvorak HF, Van de Water L. Overexpression of vascular permeability factor (VPF/VEGF) and its endothelial cell receptors in delayed hypersensitivity skin reactions. J Immunol. 1995 Mar 15; 154(6):2801-7. PMID: 7876550.
    View in: PubMed
  37. Kaczmarek E, Liu Y, Berse B, Chen CS, McDonagh J. Biosynthesis of plasma factor XIII: evidence for transcription and translation in hepatoma cells. Biochim Biophys Acta. 1995 Feb 22; 1247(1):127-34. PMID: 7873582.
    View in: PubMed
  38. Wasowska B, Wieder KJ, Hancock WW, Berse B, Binder J, Strom TB, Kupiec-Weglinski JW. Cytokine and alloantibody networks in long-term cardiac allografts in rapamycin-treated sensitized rat recipients. Transplant Proc. 1995 Feb; 27(1):423-6. PMID: 7879047.
    View in: PubMed
  39. Brown LF, Berse B, Jackman RW, Tognazzi K, Guidi AJ, Dvorak HF, Senger DR, Connolly JL, Schnitt SJ. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol. 1995 Jan; 26(1):86-91. PMID: 7821921.
    View in: PubMed
  40. Miller JW, Adamis AP, Shima DT, D'Amore PA, Moulton RS, O'Reilly MS, Folkman J, Dvorak HF, Brown LF, Berse B, et al. Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model. Am J Pathol. 1994 Sep; 145(3):574-84. PMID: 7521577.
    View in: PubMed
  41. Detmar M, Brown LF, Claffey KP, Yeo KT, Kocher O, Jackman RW, Berse B, Dvorak HF. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J Exp Med. 1994 Sep 1; 180(3):1141-6. PMID: 8064230.
    View in: PubMed
  42. Brown LF, Papadopoulos-Sergiou A, Berse B, Manseau EJ, Tognazzi K, Perruzzi CA, Dvorak HF, Senger DR. Osteopontin expression and distribution in human carcinomas. Am J Pathol. 1994 Sep; 145(3):610-23. PMID: 8080043.
    View in: PubMed
  43. Gardner HA, Berse B, Senger DR. Specific reduction in osteopontin synthesis by antisense RNA inhibits the tumorigenicity of transformed Rat1 fibroblasts. Oncogene. 1994 Aug; 9(8):2321-6. PMID: 8036014.
    View in: PubMed
  44. Fava RA, Olsen NJ, Spencer-Green G, Yeo KT, Yeo TK, Berse B, Jackman RW, Senger DR, Dvorak HF, Brown LF. Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue. J Exp Med. 1994 Jul 1; 180(1):341-6. PMID: 8006592.
    View in: PubMed
  45. Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Dvorak HF, Senger DR. Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas. Am J Pathol. 1993 Nov; 143(5):1255-62. PMID: 8238242.
    View in: PubMed
  46. Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Senger DR, Dvorak HF. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res. 1993 Oct 1; 53(19):4727-35. PMID: 8402650.
    View in: PubMed
  47. Senger DR, Van de Water L, Brown LF, Nagy JA, Yeo KT, Yeo TK, Berse B, Jackman RW, Dvorak AM, Dvorak HF. Vascular permeability factor (VPF, VEGF) in tumor biology. Cancer Metastasis Rev. 1993 Sep; 12(3-4):303-24. PMID: 8281615.
    View in: PubMed
  48. Adamis AP, Shima DT, Yeo KT, Yeo TK, Brown LF, Berse B, D'Amore PA, Folkman J. Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem Biophys Res Commun. 1993 Jun 15; 193(2):631-8. PMID: 8512562.
    View in: PubMed
  49. Dvorak HF, Nagy JA, Berse B, Brown LF, Yeo KT, Yeo TK, Dvorak AM, van de Water L, Sioussat TM, Senger DR. Vascular permeability factor, fibrin, and the pathogenesis of tumor stroma formation. Ann N Y Acad Sci. 1992 Dec 4; 667:101-11. PMID: 1309029.
    View in: PubMed
  50. Brown LF, Berse B, Tognazzi K, Manseau EJ, Van de Water L, Senger DR, Dvorak HF, Rosen S. Vascular permeability factor mRNA and protein expression in human kidney. Kidney Int. 1992 Dec; 42(6):1457-61. PMID: 1474780.
    View in: PubMed
  51. Brown LF, Yeo KT, Berse B, Yeo TK, Senger DR, Dvorak HF, van de Water L. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing. J Exp Med. 1992 Nov 1; 176(5):1375-9. PMID: 1402682.
    View in: PubMed
  52. Brown LF, Berse B, Van de Water L, Papadopoulos-Sergiou A, Perruzzi CA, Manseau EJ, Dvorak HF, Senger DR. Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces. Mol Biol Cell. 1992 Oct; 3(10):1169-80. PMID: 1421573.
    View in: PubMed
  53. Berse B, Brown LF, Van de Water L, Dvorak HF, Senger DR. Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Mol Biol Cell. 1992 Feb; 3(2):211-20. PMID: 1550962.
    View in: PubMed
  54. Dvorak HF, Sioussat TM, Brown LF, Berse B, Nagy JA, Sotrel A, Manseau EJ, Van de Water L, Senger DR. Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels. J Exp Med. 1991 Nov 1; 174(5):1275-8. PMID: 1940805.
    View in: PubMed
  55. Upshall A, Gilbert T, Saari G, O'Hara PJ, Weglenski P, Berse B, Miller K, Timberlake WE. Molecular analysis of the argB gene of Aspergillus nidulans. Mol Gen Genet. 1986 Aug; 204(2):349-54. PMID: 3020372.
    View in: PubMed
  56. Dmochowska A, Berse B, Kowalska I, Skrzypek M, Weglenski P. Expression of the Aspergillus nidulans argB gene in Escherichia coli. J Gen Microbiol. 1986 Jun; 132(6):1729-37. PMID: 3027235.
    View in: PubMed
  57. Berse B, Dmochowska A, Skrzypek M, Weglenski P, Bates MA, Weiss RL. Cloning and characterization of the ornithine carbamoyltransferase gene from Aspergillus nidulans. Gene. 1983 Nov; 25(1):109-17. PMID: 6363209.
    View in: PubMed
Brygida's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
BU Co-Authors
_
Similar BU People
_
Same Department